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Abstracts tagged "B cells and tumor necrosis factor (TNF)"

  • Abstract Number: 2772 • ACR/ARHP Annual Meeting 2015

    Activated Memory B Cells in Rheumatoid Arthritis and Relationship to Anti-TNF Treatment

    Jennifer Barnard1, Nida Meednu2, Kelly Callahan1, Andreea Coca1, Bethany A. Marston1, Ralf G. Thiele1, Darren Tabechian1, Marcy Bolster3, Jeffrey R. Curtis4, Meggan C. Mackay5, Jonathan D. Graf6, Richard Keating7, Edwin Smith8, Karen Boyle9, Lynette Keyes-Elstein9, Beverly Welch10, Ellen Goldmuntz11 and Jennifer H. Anolik1, 1University of Rochester Medical Center, Rochester, NY, 2Medicine- Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, 3MUSC, Charleston, SC, 4University of Alabama at Birmingham, Birmingham, AL, 5Autoimmune & Musculoskeletal Disorders, The Feinstein Institute for Medical Research, Manhasset, NY, 6Rosalind Russell / Ephraim P. Engleman Rheumatology Research Center, University of California, San Francisco, San Francisco, CA, 7University of Chicago, Chicago, IL, 8Dept of Med Div of Rheum, MUSC, Charleston, SC, 9Rho Federal Systems, Inc., Chapel Hill, NC, 106610 Rockledge Dr., NIAID/NIH, Bethesda, MD, 11DAIT, NIAID/NIH, Bethesda, MD

    Background/Purpose: TNF blockade is a mainstay of treatment for rheumatoid arthritis (RA), but a significant proportion of patients fail to respond to treatment or lose…

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