Abstracts tagged "B cells and tumor necrosis factor (TNF)"

Abstract Number: 2772 • 2015 ACR/ARHP Annual Meeting
Activated Memory B Cells in Rheumatoid Arthritis and Relationship to Anti-TNF Treatment
Jennifer Barnard¹, Nida Meednu², Kelly Callahan¹, Andreea Coca¹, Bethany A. Marston¹, Ralf G. Thiele¹, Darren Tabechian¹, Marcy Bolster³, Jeffrey R. Curtis⁴, Meggan C. Mackay⁵, Jonathan D. Graf⁶, Richard Keating⁷, Edwin Smith⁸, Karen Boyle⁹, Lynette Keyes-Elstein⁹, Beverly Welch¹⁰, Ellen Goldmuntz¹¹ and Jennifer H. Anolik¹, ¹University of Rochester Medical Center, Rochester, NY, ²Medicine- Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY, ³MUSC, Charleston, SC, ⁴University of Alabama at Birmingham, Birmingham, AL, ⁵Autoimmune & Musculoskeletal Disorders, The Feinstein Institute for Medical Research, Manhasset, NY, ⁶Rosalind Russell / Ephraim P. Engleman Rheumatology Research Center, University of California, San Francisco, San Francisco, CA, ⁷University of Chicago, Chicago, IL, ⁸Dept of Med Div of Rheum, MUSC, Charleston, SC, ⁹Rho Federal Systems, Inc., Chapel Hill, NC, ¹⁰6610 Rockledge Dr., NIAID/NIH, Bethesda, MD, ¹¹DAIT, NIAID/NIH, Bethesda, MD
Background/Purpose: TNF blockade is a mainstay of treatment for rheumatoid arthritis (RA), but a significant proportion of patients fail to respond to treatment or lose…

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