Abstracts tagged "B cells and immunodeficiency"

Abstract Number: 2580 • 2012 ACR/ARHP Annual Meeting
Marginal Zone Defects in Wiskott-Aldrich Syndrome Are Dependent On B Cell Intrinsic Toll-Like Receptor Signals
Shaun W. Jackson¹, Nikita Kolhatkar², Marc A. Schwartz², Socheath Khim¹ and David J. Rawlings³, ¹Seattle Children's Research Institute, Seattle, WA, ²Department of Immunology, University of Washington, Seattle, WA, ³Pediatrics/Immunology, Washington, Seattle, WA
Background/Purpose: Patients with the primary immunodeficiency Wiskott-Aldrich syndrome (WAS) have severe abnormalities in splenic marginal zone (MZ) anatomy and function. Consistent with this, WAS patients…

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Abstracts tagged "B cells and immunodeficiency"

Marginal Zone Defects in Wiskott-Aldrich Syndrome Are Dependent On B Cell Intrinsic Toll-Like Receptor Signals