Abstracts tagged "B cells and immune activation"

Abstract Number: 28 • 2018 ACR/ARHP Annual Meeting
The Rho Kinase Family Member, ROCK2, Promotes Germinal Center Responses and Is Required for Optimal Humoral Immunity
Edd Ricker¹, Chao Ye², Danny Flores-Castro², Sanjay Gupta³, Michela Manni¹, Yurii Chinenov⁴, Tania Pannellini², James K. Liao⁵ and Alessandra B. Pernis⁶, ¹Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, NY, ²Hospital for Special Surgery, New York, NY, ³Autoimmunity & Inflammation Research Program, Hospital for Special Surgery, New York, NY, ⁴Arthritis & Tissue Degeneration Program, Hospital for Special Surgery, New York, NY, ⁵Cardiology Section, University of Chicago Medical Center, Chicago, IL, ⁶David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, NY
Background/Purpose: Rho GTPases, such as RhoA, are emerging as important regulators of lymphocyte biology owing to their ability to be rapidly activated downstream of a…

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Abstracts tagged "B cells and immune activation"

The Rho Kinase Family Member, ROCK2, Promotes Germinal Center Responses and Is Required for Optimal Humoral Immunity