Abstracts tagged "B cells and flow cytometry"

Abstract Number: 2420 • 2019 ACR/ARP Annual Meeting
Role of T Follicular Helper Cells and T Peripheral Helper Cells in the Activation of B Cells in Sjögren Syndrome
Anastasia Dupré¹, Juliette Pascaud ¹, Elodie Rivière ², Michael Mingueneau ³, Gaetane Nocturne ⁴ and Xavier Mariette ⁵, ¹IMVA - IDMIT, CEA - Université Paris Sud - INSERM U1184, Le Kremlin Bicêtre, Paris, France, ²IDMIT, CEA - Université Paris Sud - INSERM U1184, Le Kremlin Bicêtre ; Arthritis R&D, France, Paris, France, ³Biomarker Discovery Platform UTechS CB, Hub de Bioinformatique et biostatistique, C3IB, Institut Pasteur, Paris, France, ⁴Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique – Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM, Paris, France., Paris, France, ⁵Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique – Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM, Paris, France
Background/Purpose: Primary Sjögren's Syndrome (pSS) is a rare systemic autoimmune disease characterized by a dysregulation of cellular and humoral immunity, leading to a hyper-activation of…

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