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Abstracts tagged "B cell targeting and inflammation"

  • Abstract Number: 959 • 2019 ACR/ARP Annual Meeting

    A Novel Image Analysis Program, “CytoSkaler”, Demonstrates That Anti-Vimentin Antibody Affinity Maturation in Lupus Tubulointerstitial Nephritis Also Results in More Selective Antigen Targeting

    Andrew Kinloch1, Aazam Mohsin 1, Yuta Asano 1, Carole Henry 1, Nirit Mor Vaknin 2, Maureen Legendre 2, Patrick Wilson 1, David Markovitz 2 and Marcus Clark 1, 1University of Chicago, Chicago, IL, 2University of Michigan, Ann Arbor, MI

    Background/Purpose: Vimentin is a dominant target of B-cells selected in lupus tubulointerstial inflammation (TII), a predictor of renal failure. The origins of anti-vimentin antibodies (AVA)…
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ACR Convergence: Where Rheumatology Meets. All Virtual. November 5-9.

ACR Pediatric Rheumatology Symposium 2020

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