Abstracts tagged "axial spondyloarthritis"

Abstract Number: 562 • 2019 ACR/ARP Annual Meeting
Development of a Set of ASAS Quality Standards for Adults with Axial Spondyloarthritis
Uta Kiltz¹, Robert B.M. Landewé ², Désirée van der Heijde ³, Martin Rudwaleit ⁴, Michael Weisman ⁵, Nurullah Akkoç ⁶, Annelies Boonen ⁷, Jan Brandt-Jürgens ⁸, Philippe Carron ⁹, Maxime Dougados ¹⁰, Laure Gossec ¹¹, Merryn Jongkees ¹², Pedro Machado ¹³, Helena Marzo-Ortega ¹⁴, Anna Molto ¹⁵, Victoria Navarro-Compán ¹⁶, Karin Niedermann-Schneider ¹⁷, Percival Degrava Sampaio-Barros ¹⁸, Gleb Slobodin ¹⁹, Filip Van den Bosch ⁹, Astrid van Tubergen ²⁰, Salima van weely ²¹, Dieter Wiek ²² and Jürgen Braun ²³, ¹Rheumazentrum Ruhrgebiet/Ruhr University Bochum, Herne, Germany, Herne, Germany, ²Amsterdam University Medical Center, Amsterdam, Netherlands, ³Leiden University Medical Center, Leiden, Netherlands, ⁴Klinikum Bielefeld, Charité Berlin, Gent University, Bielefeld, Germany, ⁵David Geffen School of Medicine at UCLA, Los Angeles, CA, ⁶Division of Rheumatology, Celal Bayar University School of Medicine, Manisa, Turkey, Manisa, Turkey, ⁷Maastricht University Medical Center, Maastricht, Netherlands, ⁸Rheumatologische Schwerpunktpraxis, Berlin, Germany, ⁹Ghent University Hospital, Ghent, Belgium, ¹⁰10Rheumatology B Department, Paris Descartes University, Cochin Hospital, Paris, France, ¹¹Sorbonne Université and Hôpital Pitié-Salpêtrière, Paris, France, ¹²seaynmedical, Netherlands, Netherlands, ¹³Centre for Rheumatology & MRC Centre for Neuromuscular Diseases, University College London, London, United Kingdom, ¹⁴NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, University of Leeds, Leeds, Leeds, United Kingdom, ¹⁵Paris Descartes University, Medicine Faculty; APHP, Rheumatology, Hôpital Cochin, Hôpitaux de Paris, Paris, Paris, France, ¹⁶University Hospital La Paz, IdiPaz, Madrid, Spain, ¹⁷ZHAW Gesundheit Institut für Physiotherapie, Winterthur, Switzerland, ¹⁸Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR, Brazil, Sao Paulo, Brazil, ¹⁹18Department of Internal Medicine A, Bnai Zion Medical Center, Technion, Haifa, Israel, ²⁰Maastricht University Medical Centre and Care and Public Health Research Institute (CAPHRI), Maastricht, Netherlands, ²¹Orthopedics, Rehabilitation and Physical Therapy dpt., Leiden University Medical Center, Leiden, Netherlands, ²²patient research partner, Germany, Germany, Germany, ²³Rheumazentrum Ruhrgebiet/Ruhr University, Herne, Germany
Background/Purpose: There is wide variation in the management of patients with axial spondyloarthritis (axSpA) worldwide with significant unmet needs such as delayed diagnosis. One way…
Abstract Number: 601 • 2019 ACR/ARP Annual Meeting
Development of an Optimized Online Self-Referral Tool for Early Recognition of Patients with Axial Spondyloarthritis – Data from the OptiRef Study
Fabian Proft¹, Laura Spiller ², Mikhail Protopopov ³, Valeria Rios Rodriguez ², Burkhard Muche ², Judith Rademacher ², Susanne Lüders ², Anne Katrin Weber ², Imke Redeker ⁴ and Denis Poddubnyy ⁵, ¹Charité Universitätsmedizin Berlin, Germany, Berlin, Germany, ²Charité Universitätsmedizin, Berlin, Germany, ³Charité Universitätsmedizin Berlin, Germany, Berlin, Berlin, Germany, ⁴Charité – Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, ⁵Charité - Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany
Background/Purpose: One of the major reasons for a long diagnostic delay in axial spondyloarthritis (axSpA) is the late referral of patients by primary care physicians…
Abstract Number: 635 • 2019 ACR/ARP Annual Meeting
Association Between Radiographic Progression and Cardiovascular Risk in Spondyloarthritis: Data from CoSpaR REGISTRY
María Lourdes Ladehesa-Pineda¹, Maria Carmen Castro ², Ignacio Gomez-Garcia ², Pedro Seguí-Azpilcueta ³, María del carmen ábalos-Aguilera ⁴, Rocío Segura-Ruiz ⁵, Rafaela Ortega ², Laura Bautista-Aguilar ⁶, Inmaculada Aranda-Varela ⁷, Clementina López-Medina ⁸, Juan Luis Garrido-Castro ⁹, Chary Lopez-Pedrera ², Alejandro Escudero-Contreras ⁷, Eduardo Collantes-Estévez ⁷ and Yolanda Jiménez-Gómez ⁴, ¹Universitary Hospital Reina Sofia of Cordoba/University of Cordoba/IMIBIC, Córdoba, Spain, ²IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Spain, ³Universitary Hospital Reina Sofía of Córdoba, Córdoba, Spain, ⁴IMIBIC, Córdoba, Spain, ⁵Reina Sofia University Hospital/IMIBIC, Córdoba, Spain, ⁶[email protected], Córdoba, Spain, ⁷Universitary Hospital Reina Sofía of Córdoba/University of Córdoba/IMIBIC, Córdoba, Spain, ⁸Cochin Hospital, Rheumatology Department, Paris, France, ⁹University of Córdoba, Córdoba, Spain
Background/Purpose: Our objectives are:To analyze the prevalence of comorbidities related to CV risk in a register of patients with spondyloarthritis (CoSpaR).To evaluate if there is…
Abstract Number: 1478 • 2019 ACR/ARP Annual Meeting
Systematic Literature Review and Network Meta-Analysis Comparing Incidence of Uveitis and IBD in Axial Spondyloarthritis Patients Treated with Anti-TNF versus Anti-IL17A in Placebo Controlled Randomized Trials
Damien Roche¹, Martin Badard ¹, Laurent Boyer ², Pierre Lafforgue ¹ and Thao Pham ¹, ¹Aix-Marseille University, CHU Marseille, department of Rheumatology, 13,000 Marseille, France, Marseille, France, ²Aix-Marseille University, EA 3279 Research Unit, 13,000 Marseille, France, Marseille, France
Background/Purpose: Inflammatory bowel diseases (IBD) and anterior uveitis (AU) are frequent extra-articular features of axial spondyloarthritis (axSpA). Although effect of anti-TNF on IBD and AU…
Abstract Number: 1546 • 2019 ACR/ARP Annual Meeting
Effectiveness and Retention Rate of Secukinumab for Psoriatic Arthritis and Axial Spondyloarthritis: Real-life Data from the Italian LORHEN Registry
Ennio Giulio Favalli ¹, Antonio Marchesoni ¹, Silvia Balduzzi ², Carlomaurizio Montecucco ³, Claudia Lomater ⁴, Gloria Crepaldi ⁴, Silvia Tamanini ⁵, Chiara Bazzani ⁶, Enrico Fusaro ⁷, Marta Priora ⁷, Aurora Ianniello ⁸ and Roberto Caporali¹, ¹University of Milan, Department of Rheumatology, ASST Gaetano Pini-CTO, Milan, Lombardia, Italy, ²Department of Rheumatology, IRCCS Policlinico S. Matteo Foundation, University of Pavia, Pavia, Italy, Pavia, Lombardia, Italy, ³Department of Rheumatology, IRCCS Policlinico S. Matteo Foundation, University of Pavia, Pavia, Italy, Pavia, Italy, ⁴AO Ordine Mauriziano, SSD Reumatologia, Torino, Turin, Piemonte, Italy, ⁵ASST Spedali Civili and University of Brescia, Milan, Lombardia, Italy, ⁶Rheumatology and Clinical Immunology, Spedali Civili, Brescia, Italy, Brescia, Italy, ⁷A.O.U. Città della Salute e della Scienza di Torino, SC Reumatologia, Turin, Piemonte, Italy, ⁸Day Hospital Multidisciplinare PO SS. Trinità, Borgomanero, Borgomanero, Piemonte, Italy
Background/Purpose: Observational data on the use of secukinumab for the treatment of spondyloarthritides are still lacking. The aim of this study is to evaluate the…
Abstract Number: 2775 • 2019 ACR/ARP Annual Meeting
Pregnancy Rates and Outcomes in Early Axial Spondyloarthritis: Analysis of the DESIR Cohort
Marion Pons ¹, Nathalie Costedoat-Chalumeau ², Karine Briot ³, Philippe Goupille ⁴, Christian Roux ⁵, Maxime Dougados ⁶ and Anna Moltó⁵, ¹Rheumatology department, Cochin Hospital, Paris, Paris, Ile-de-France, France, ²Cochin University Hospital, Paris, France, ³Rheumatology department, Cochin Hospital, Paris, France, Paris, Ile-de-France, France, ⁴Tours University-Hospital, Tours, France, Tours, France, ⁵Paris Descartes University, Cochin Hospital, Rheumatology department, Paris, France, ⁶Cochin Hospital, Paris, France
Background/Purpose: Only scarce data is available on regarding pregnancy rates and pregnancy outcomes in early axial spondyloarthritis (axSpA). The objectives of this study were to…
Abstract Number: 563 • 2019 ACR/ARP Annual Meeting
The Impact of Sex and Disease Classification on Patient-reported Outcome Measures in Axial Spondyloarthritis: A Descriptive Prospective Cross-sectional Study
Rikke Andreasen¹, Lars Erik Kristensen ², Kenneth Egstrup ¹, Xenofon Baraliakos ³, Vibeke Strand ⁴, Hans Christian Horn ⁵, Inger Marie Hansen ¹, Robin Christensen ⁶ and Torkell Ellingsen ⁷, ¹Odense University Hospital, Svendborg, Svendborg, Denmark, ²Musculoskeletal Statistics Unit, the Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Copenhagen, Denmark, ³Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Germany, Herne, Germany, ⁴Division of Immunology/Rheumatology, Stanford University, Stanford, CA, ⁵Research Unit of Rheumatology, Department of Clinical Research, University of Southern Denmark, Odense University Hospital, Denmark, Odense, Denmark, ⁶Musculoskeletal Statistics Unit, The Parker Institute, Bispebjerg and Frederiksberg Hospital & Department of Rheumatology, Institute of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark, ⁷Department of Rheumatology, Odense University Hospital, Denmark, Odense, Syddanmark, Denmark
Background/Purpose: To explore the impact of sex and disease classification on outcomes in axial spondyloarthritis (axSpA) patients, including both ankylosing spondylitis (AS) and non-radiographic (nr-)…
Abstract Number: 603 • 2019 ACR/ARP Annual Meeting
Are the Modified New York and ASAS Criteria Interchangeable in the Classification of Patients with Spondyloarthritis with Radiographic Sacroiliitis?
Anne Boel¹, Anna Moltó ², Désirée van der Heijde ³, Adrian Ciurea ⁴, Maxime Dougados ⁵, Lianne Gensler ⁶, Maria José Santos ⁷, Eugenio de Miguel ⁸, Denis Poddubnyy ⁹, Martin Rudwaleit ¹⁰, Astrid van Tubergen ¹¹, Floris van Gaalen ³ and Sofia Ramiro ¹², ¹Leiden University Medical Centre, Leiden, Netherlands, ²Paris Descartes University, Cochin Hospital, Rheumatology department, Paris, France, ³Leiden University Medical Center, Leiden, Netherlands, ⁴University Hospital Zürich, Zürich, Switzerland, ⁵Cochin Hospital, Paris, France, ⁶University San Francisco California, San Francisco, CA, ⁷Rheumatology department, Hospital Garcia de Orta, Almada, Portugal, ⁸Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain, ⁹Charité - Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany, ¹⁰Klinikum Bielefeld, Charité Berlin, Gent University, Bielefeld, Germany, ¹¹Maastricht University Medical Centre and Care and Public Health Research Institute (CAPHRI), Maastricht, Netherlands, ¹²Leiden University Medical Center and Zuyderland Medical Centre, Leiden, Netherlands
Background/Purpose: Patients with axial spondyloarthritis (axSpA) with radiographic sacroiliitis may be classified using the modified New York (mNY) criteria as ankylosing spondylitis and using the…
Abstract Number: 748 • 2019 ACR/ARP Annual Meeting
Takayasu Arteritis and Sacroiliitis: A Case Control Study in 28 Patients of a Single Italian Center
Paola Toniati¹, Francesca Regola ¹, Franco Franceschini ¹, Giovanni Bosio ² and Angela Tincani ³, ¹Rheumatology and Clinical Immunology Unit, ASST Spedali Civili and University of Brescia, Brescia, Italy, Brescia, Italy, ²Nuclear Medicine Unit, ASST Spedali Civili of Brescia, Brescia, Italy, Brescia, Italy, ³Rheumatology and Clinical Immunology, Spedali Civili and Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy, Brescia, Italy
Background/Purpose: A lot of clinical case descriptions about spondyloarthropathy in TAK patients were reported. Recently, a paper about an increased incidence of spondyloarthropathy in TAK…
Abstract Number: 1482 • 2019 ACR/ARP Annual Meeting
Secukinumab Provides Sustained Improvement of Enthesitis in Ankylosing Spondylitis Patients: A Pooled Analysis of Four Pivotal Phase 3 Trials
Georg Schett¹, Xenofon Baraliakos ², Filip Van den Bosch ³, Atul Deodhar ⁴, Lianne Gensler ⁵, Mikkel Østergaard ⁶, Shital Agawane ⁷, Ayan Das Gupta ⁷, Shephard Mpofu ⁸, Todd Fox ⁸, Adam Winseck ⁹, Brian Porter ⁹ and Abhijit Shete ⁸, ¹Department of Internal Medicine 3, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany, ²Rheumazentrum Ruhrgebiet-Ruhr-University Bochum, Herne, Germany, Herne, Germany, ³Ghent University Hospital, Ghent, Belgium, ⁴Oregon Health & Science University, Portland, OR, ⁵University San Francisco California, San Francisco, CA, ⁶Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark, ⁷Novartis Healthcare Pvt Ltd, Hyderabad, India, ⁸Novartis Pharma AG, Basel, Switzerland, ⁹Novartis Pharmaceuticals Corporation, East Hanover, NJ
Background/Purpose: Enthesitis can be a debilitating spondyloarthritis (SpA) manifestation and the cause of pain, reduced quality of life and impaired physical function.1,2 Herein, we evaluated…
Abstract Number: 1547 • 2019 ACR/ARP Annual Meeting
Ixekizumab Improves Self-reported Overall Functioning and Health as Measured by the Assessment of SpondyloArthritis International Society Health Index in Patients with Active Radiographic Axial Spondyloarthritis: 52-Week Results of Two Phase 3 Randomized Trials
Uta Kiltz¹, Désirée van der Heijde ², Annelies Boonen ³, Lianne Gensler ⁴, Theresa Hunter ⁵, Fangyi Zhao ⁶, Baojin Zhu ⁵, Rebecca Bolce ⁵, Hilde Carlier ⁵ and Jürgen Braun ⁷, ¹Rheumazentrum Ruhrgebiet/Ruhr University Bochum, Herne, Germany, Herne, Germany, ²Leiden University Medical Center, Leiden, Netherlands, ³Maastricht University Medical Center, Maastricht, Netherlands, ⁴University San Francisco California, San Francisco, CA, ⁵Eli Lilly and Company, Indianapolis, ⁶Eli Lilly and Company, Indianapolis, IN, ⁷Rheumazentrum Ruhrgebiet/Ruhr University, Herne, Germany
Background/Purpose: The Assessment of SpondyloArthritis international Society Health Index (ASAS HI) measures health, disability, and functioning in patients (pts) with spondyloarthritis (SpA)[1,2]. The purpose of…
Abstract Number: 2776 • 2019 ACR/ARP Annual Meeting
5-years Treatment Effect of TNF Alpha Inhibitor in Early Axial Spondyloarthritis and Associated Factors: An Inverse Probability Weighting Analysis of the DESIR Cohort
Marion Pons ¹, Sylvie Chevret ², Karine Briot ¹, Maria-Antonietta D’Agostino ³, Christian Roux ⁴, Maxime Dougados ⁵ and Anna Moltó⁴, ¹Rheumatology department, Cochin Hospital, Paris, Paris, Ile-de-France, France, ²INSERM U-1153, CRESS Paris-Sorbonne, Paris, Paris, Ile-de-France, France, ³Department of Rheumatology, APHP, Hôpital Ambroise Paré, Paris, France, ⁴Paris Descartes University, Cochin Hospital, Rheumatology department, Paris, France, ⁵Cochin Hospital, Paris, France
Background/Purpose: Only scarce date is available on the long term treatment effect in a real-life setting (i.e. effectiveness) of TNFi in early axial SpA forms…
Abstract Number: 1024 • 2018 ACR/ARHP Annual Meeting
Unique Pattern of Lectin Pathway Complement Protein Levels in Axial Spondyloarthritis
Anne Troldborg^1,2,3, Steffen Thiel¹, Clara Mistegaard Joergensen⁴, Kristian Stengaard-Pedersen^3,5 and Anne Gitte Loft^3,6, ¹Biomedicine, Aarhus University, Aarhus, Denmark, ²clinical medicine, Aarhus University, Aarhus, Denmark, ³Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ⁴Emergency Medicine, Regional Hospital Horsens, Horsens, Denmark, ⁵Clinical medicine, Aarhus University, Aarhus, Denmark, ⁶Clinical Medicine, Aarhus University, Aarhus, Denmark
Background/Purpose: Spondyloarthritis (SpA) represents a group of immune-mediated inflammatory diseases that exhibit overlapping clinical features, genetic predisposition and a not fully understood pathogenesis. Inflammation and…
Abstract Number: 2558 • 2018 ACR/ARHP Annual Meeting
Efficacy and Safety Outcomes in Patients with Axial Spondyloarthritis Treated with Certolizumab Pegol: Results from the 48-Week Run-in Part of a Withdrawal Study (NCT02505542)
Robert B.M. Landewé¹, Désirée van der Heijde², Maxime Dougados³, Xenofon Baraliakos⁴, Filip van Den Bosch⁵, Bengt Hoepken⁶, Karen Thomas⁶ and Lianne S. Gensler⁷, ¹Amsterdam Rheumatology & Clinical Immunology Center, Amsterdam and Zuyderland MC, Heerlen, Netherlands, ²Leiden University Medical Centre, Leiden, Netherlands, ³Rheumatology B Department, Paris-Descartes University and Cochin Hospital, Paris, France, ⁴Ruhr-University Bochum, Herne, Germany, ⁵Department of Internal Medicine, Ghent University Hospital, Ghent, Belgium, ⁶UCB Pharma, Monheim, Germany, ⁷University of California, San Francisco, CA
Background/Purpose: C-OPTIMISE is the first trial to evaluate whether certolizumab pegol (CZP) can be reduced/discontinued in patients with radiographic(r)-axSpA/ankylosing spondylitis (AS) and non-radiographic(nr)-axSpA achieving sustained…
Abstract Number: 1616 • 2018 ACR/ARHP Annual Meeting
Region-Specific Differences in Clinical Presentation of Patients with Axial Spondyloarthritis – Results from a Large Multinational Cohort Study
Denis Poddubnyy¹, Robert D Inman², Joachim Sieper¹, Fabiana Ganz³ and Maja Hojnik⁴, ¹Charité Universitätsmeidzin Berlin, Berlin, Germany, ²Department of Medicine, University of Toronto, Toronto, ON, Canada, ³AbbVie, Baar, Switzerland, ⁴AbbVie, Ljubljana, Slovenia
Background/Purpose: There is limited evidence on the phenotypic characteristics of axial spondyloarthritis (axSpA) patients (pts) in various geographic regions around the world. This analysis aimed…

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