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Abstracts tagged "axial spondyloarthritis"

  • Abstract Number: 2745 • 2016 ACR/ARHP Annual Meeting

    Adult Axial Spondyloarthritis Screening and Referral Practices Amongst Primary Care Physicians, Physiotherapists, Chiropractors and Nurse Practitioners:  Results from a Qualitative Study

    Laura Passalent1,2, Leslie Soever2,3, Kathleen Bednis1, Christopher Hawke1,4, Andrew Bidos5,6, Jeff Bloom7,8, Y. Raja Rampersaud6,8, Nigil Haroon9,10 and Robert D Inman8,9, 1Allied Health, Toronto Western Hospital, Toronto, ON, Canada, 2Physical Therapy, University of Toronto, Toronto, ON, Canada, 3MSK, Geriatrics and Cardiac Rehab Programs, University Health Network, Toronto, ON, Canada, 4Department of Physical Therapy, University of Toronto, Toronto, ON, Canada, 5Health Quality Programs - ISAEC, University Health Network, Toronto, ON, Canada, 6Orthopaedics, Toronto Western Hospital, Toronto, ON, Canada, 7Family Medicine, Toronto Western Hospital, Toronto, ON, Canada, 8University of Toronto, Toronto, ON, Canada, 9Rheumatology, Toronto Western Hospital, University of Toronto, Spondylitis Clinic, Toronto, ON, Canada, 10Rheumatology, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose:  For the axial spondyloarthritis (SpA) population, early recognition is crucial in preventing major morbidity. Despite this, there exists an unacceptably long delay between the…
  • Abstract Number: 688 • 2016 ACR/ARHP Annual Meeting

    Spondyloarthritis Research Consortium of Canada (SPARCC) Baseline MRI SI Joint Score ≥2 Better Predicts Response to Golimumab Than Does Assessment of Spondyloarthritis International Society (ASAS) MRI Positivity in Nonradiographic Axial Spondyloarthritis

    Walter Maksymowych1, Anjela Tzontcheva2, George Philip2, Gina Bergman2, Susan Huyck2 and Sean P. Curtis2, 1Medicine, University of Alberta, Edmonton, AB, Canada, 2Merck & Co., Inc., Kenilworth, NJ

    Background/Purpose: Golimumab (GLM) was shown to be effective for nonradiographic axial spondyloarthritis (nr-axSpA) in a randomized, double-blind, placebo-controlled, phase 3 study (GO-AHEAD; NCT01453725).1 The SPondyloArthritis…
  • Abstract Number: 2754 • 2016 ACR/ARHP Annual Meeting

    Self-Reported Physical Activity Questionnaire in Axial Spondyloarthritis: Modification of the Squash

    Fiona Maas1, Anna Jetske Baron1,2, Freke Wink3, Reinhard Bos3, Yvo Kamsma2, Hendrika Bootsma4, Suzanne Arends1,3 and Anneke Spoorenberg1,3, 1Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 2Center for Human Movement Sciences, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 3Rheumatology, Medical Center Leeuwarden, Leeuwarden, Netherlands, 4Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, The Netherlands, Groningen, Netherlands

    Background/Purpose:  Improvement of physical function and physical activity are important goals in the management of axial spondyloarthritis (axSpA). Although physical function is included in the…
  • Abstract Number: 697 • 2016 ACR/ARHP Annual Meeting

    Does Axial Spondyloarthritis Phenotype Correlate with Imaging Morphotype?

    Xenofon Baraliakos1, Annette Szumski2, Heather Jones3 and Lianne S. Gensler4, 1Rheumazentrum, Ruhr University, Bochum, Germany, 2inVentiv Health, Princeton, NJ, 3Inflammation & Immunology, Pfizer, Collegeville, PA, 4Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA

    Background/Purpose: Traditionally, radiographic imaging was used to describe morphological differences between various types of axial SpA (axSpA). MRI has advanced understanding of disease, enabled earlier…
  • Abstract Number: 2779 • 2016 ACR/ARHP Annual Meeting

    Better Health-Related Quality of Life and Work Capacity in Patients Achieving Inactive Disease and Clinical Response in Patients with Non-Radiographic Axial Spondyloarthritis

    Maxime Dougados1, Desiree van der Heijde2, Wen-Chan Tsai3, Diego Saaibi4, Randi Bonin5, Lisa Marshall6, Heather Jones7, Ronald Pedersen8, Bonnie Vlahos9 and Miriam Tarallo10, 1Rheumatology, Paris Descartes University, Paris, France, 2Leiden University Medical Center, Leiden, Netherlands, 3Kaohsiung Medical University, Kaohsiung City, Taiwan, 4MEDICITY S.A.S, Bucaramanga, Colombia, 5Clinical Affairs, Pfizer, Collegeville, PA, 6Inflammation Global Medical Affairs, Pfizer, Collegeville, PA, 7Inflammation & Immunology, Pfizer, Collegeville, PA, 8Department of Biostatistics, Pfizer, Collegeville, PA, 9GIPB - Clinical Sciences, Pfizer, Collegeville, PA, 10GHV, Pfizer, Rome, Italy

    Background/Purpose: Few studies have evaluated the relationship between disease activity/clinical response and patient-reported outcomes (PROs) of pain, fatigue, health-related quality of life (HRQoL), and work…
  • Abstract Number: 706 • 2016 ACR/ARHP Annual Meeting

    Performance of the ASAS Classification Criteria for Axial and Peripheral Spondyloarthritis – a Systematic Literature Review and Meta-Analysis

    Alexandre Sepriano1, Roxana Rubio1, Sofia Ramiro1, Robert Landewé2 and Désirée van der Heijde3, 1Leiden University Medical Center, Leiden, Netherlands, 2Amsterdam Rheumatology & Immunology Center, Amsterdam, Netherlands, 3Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: The Assessment of SpondyloArthritis international Society (ASAS) has developed and validated classification criteria for axial spondyloarthritis (axSpA) and peripheral SpA (pSpA). Following their release,…
  • Abstract Number: 3010 • 2016 ACR/ARHP Annual Meeting

    Improvement of Spinal Inflammation Induced By Etanercept in Enthesitis Related Arthritis JIA-Patients. Data of the Reminder-Study

    Gerd Horneff1, Ivan Foeldvari2, Kirsten Minden3,4, Hans-Iko Huppertz5 and Ariane Klein6, 1Department of Pediatrics, Centre of Pediatric Rheumatology, Sankt Augustin, Germany, 2Kinder- und Jugenrheumatologie, Hamburger Zentrum Kinder-und Jugendrheumatologie, Hamburg, Germany, 3Epidemiology, Charite, DRFZ, Berlin, Germany, 4Children’s University Hospital Charite/German Rheumatism Research Centre Berlin, Berlin, Germany, 5Klinikum Bremen-Mitte, Prof.-Hess-Kinderklinik, Bremen, Germany, 6Center of Pediatrics and Neonatology, Asklepios Clinic Sankt Augustin, Sankt Augustin, Germany

    Background/Purpose: The data of the REMINDER study, a two-part, 48-week, randomized, placebo-controlled, double-blind withdrawal study on efficacy of etanercept (ETA) compared to placebo (PLC) in…
  • Abstract Number: 733 • 2016 ACR/ARHP Annual Meeting

    Efficacy and Safety of Non-Biological Therapy (Non-Biological Drugs and Non-Pharmacological Interventions): A Systematic Literature Review for the 2016 Update of the ASAS/EULAR Recommendations for the Management of Axial Spondyloarthritis

    Andrea Regel1, Alexandre Sepriano2, Xenofon Baraliakos1, Désirée van der Heijde2, Juergen Braun1, Robert Landewé3, Filip van Den Bosch4 and Sofia Ramiro2, 1Rheumazentrum Ruhrgebiet, Herne, Germany, 2Leiden University Medical Center, Leiden, Netherlands, 3Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, Netherlands, 4Rheumatology, Ghent University Hospital, Ghent, Belgium

    Background/Purpose: As part of the 2016 update of the ASAS/EULAR recommendations for the management of axSpA, we performed a systematic literature review (SLR) to assess…
  • Abstract Number: 3037 • 2016 ACR/ARHP Annual Meeting

    Calprotectin Is Highly Upregulated in Inflamed Axial Entheses in SKG Mice

    Zheni Stavre1, Yukiko Maeda2 and Ellen M. Gravallese3, 1Internal Medicine-Rheumatology, University of Massachusetts Medical School, Worcester, MA, 2Medicine, University of Massachusetts Medical School, Worcester, MA, 3Lazare Research Bldg, University of Massachusetts Medical School, Worcester, MA

    Background/Purpose:  SKG mice exhibit features of spondyloarthropathy (SpA) and inflammatory bowel disease (IBD). Their SpA-like phenotype is induced by a beta-glucan, curdlan, via the Dectin-1…
  • Abstract Number: 930 • 2016 ACR/ARHP Annual Meeting

    How to Implement Cardiovascular Disease Risk Assessment for Patients with Inflammatory Joint Diseases in Daily Rheumatology Practice: An Overview of a Nationwide Norwegian Project

    Eirik Ikdahl1, Silvia Rollefstad2, Grunde Wibetoe3, Anne Salberg4, Dag Magnar Soldal5, Inge C Olsen6, Tore K Kvien6, Glenn Haugeberg7 and Anne Grete Semb1, 1Preventive Cardio-Rheuma clinic, Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 2Preventive Cardio-Rheuma Clinic, Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 3Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Hospital for Rheumatic Diseases, Lillehammer, Norway, 5Rheumatology, Hospital of Southern Norway, Kristiansand, Norway, 6Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 7Martina Hansens Hospital, Bærum, Norway

    Background/Purpose:  The EULAR recommendations for cardiovascular disease (CVD) risk management in patients with inflammatory joint diseases (IJD) states that CVD risk assessment should be considered…
  • Abstract Number: 3162 • 2016 ACR/ARHP Annual Meeting

    Symmetric and Asymmetric Sacroiliitis Are Associated with Different Major Histocompatibility Class I Alleles in Psoriatic Arthritis

    Jon T. Giles1, Muhammad Haroon2, Deepak R. Jadon3, Raj Sengupta4, Alison L Nightingale5, Eleanor Korendowych3, Jing Bi6, Neil J. McHugh3, Oliver FitzGerald7 and Robert Winchester6, 1Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, 2Rheumatology, Kerry General Hospital, Co Kerry, Ireland, 3Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 4Rheumatology, Royal National Hospital for Rheumatic Diseases,, Bath, United Kingdom, 5Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom, 6Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, 7St. Vincent's University Hospital, Department of Rheumatology, Dublin, Ireland

    Background/Purpose: HLA-B27 has been linked to sacroiliitis (SII) in psoriatic arthritis (PsA); however, the contribution to SII of other human leukocyte antigen (HLA) Class I…
  • Abstract Number: 1042 • 2016 ACR/ARHP Annual Meeting

    Four Year Imaging Outcomes in Patients with Axial Spondyloarthritis Treated with Certolizumab Pegol, Including Patients with Ankylosing Spondylitis and Non-Radiographic Axial Spondyloarthritis

    Desiree van der Heijde1, Xenofon Baraliakos2, Kay-Geert Hermann3, Robert Landewé4, Pedro Machado5, Walter Maksymowych6, Owen Davies7, Natasha de Peyrecave7, Bengt Hoepken8, Lars Bauer8, Tommi Nurminen8 and Jürgen Braun9, 1Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Rheumazentrum Ruhrgebiet, Ruhr-University Bochum, Herne, Germany, 3Charité – University Medicine Berlin, Berlin, Germany, 4Rheumatology, Academic Medical Center, Amsterdam & Zuyderland Medical Center Heerlen, Amsterdam, Netherlands, 5Centre for Rheumatology Research & MRC Centre for Neuromuscular Diseases, University College London, London, United Kingdom, 6Medicine, Department of Medicine, University of Alberta, Edmonton, AB, Canada, 7UCB Pharma, Slough, United Kingdom, 8UCB Pharma, Monheim, Germany, 9Rheumazentrum Ruhrgebiet, Herne, Germany

    Background/Purpose: RAPID-axSpA (NCT01087762) was a long-term study in patients (pts) with axial spondyloarthritis (axSpA) treated with certolizumab pegol (CZP). This is the first report of…
  • Abstract Number: 1163 • 2016 ACR/ARHP Annual Meeting

    Impact of E-Learning on Perceived Social Role Participation of Patients with Axial Spondyloarthritis: Results from a Longitudinal Randomized Control Trial

    Daeria Lawson1, Laura Passalent2,3, Rita Kang4, Christopher Hawke2,5, Ahmed Omar6,7, Arane Thavaneswaran1, Nigil Haroon8,9 and Robert D Inman6,10, 1Toronto Western Hospital, Toronto, ON, Canada, 2Allied Health, Toronto Western Hospital, Toronto, ON, Canada, 3Physical Therapy, University of Toronto, Toronto, ON, Canada, 4Patient and Family Education, Toronto Western Hospital, Toronto, ON, Canada, 5Department of Physical Therapy, University of Toronto, Toronto, ON, Canada, 6Rheumatology, Toronto Western Hospital, University of Toronto, Spondylitis Clinic, Toronto, ON, Canada, 7Rheumatology, University of Toronto, Toronto, ON, Canada, 8Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, 9Medicine, Rheumatology, University of Toronto, Toronto, ON, Canada, 10University of Toronto, Toronto, ON, Canada

    Background/Purpose: The purpose of this study was to Methods:  Fifty-six adult patients with axSpA attending a tertiary academic spondyloarthritis clinic were randomly assigned to one…
  • Abstract Number: 1164 • 2016 ACR/ARHP Annual Meeting

    Impact of E-Learning on Knowledge, Self-Efficacy and Exercise Behaviours of Patients with Axial Spondyloarthritis: Results from a Longitudinal Randomized Control Trial

    Laura Passalent1,2, Rita Kang3, Daeria Lawson4, Christopher Hawke1,5, Ahmed Omar6,7, Arane Thavaneswaran4, Nigil Haroon8,9 and Robert D Inman7,10, 1Allied Health, Toronto Western Hospital, Toronto, ON, Canada, 2Physical Therapy, University of Toronto, Toronto, ON, Canada, 3Patient and Family Education, Toronto Western Hospital, Toronto, ON, Canada, 4Toronto Western Hospital, Toronto, ON, Canada, 5Department of Physical Therapy, University of Toronto, Toronto, ON, Canada, 6Rheumatology, University of Toronto, Toronto, ON, Canada, 7Rheumatology, Toronto Western Hospital, University of Toronto, Spondylitis Clinic, Toronto, ON, Canada, 8Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, 9Medicine, Rheumatology, University of Toronto, Toronto, ON, Canada, 10University of Toronto, Toronto, ON, Canada

    Background/Purpose:  There is a growing body of evidence to support the effectiveness of education programs for patients with arthritis. Despite this, there has been little development…
  • Abstract Number: 1240 • 2016 ACR/ARHP Annual Meeting

    A Minority of Patients Utilize Most of Healthcare Resources in Rheumatoid Arthritis, Psoriatic Arthritis, Juvenile Idiopathic Arthritis, and Axial Spondyloarthritis

    Nina Mars1, Anne M Kerola2, Markku J Kauppi3,4, Outi Elonheimo5,6, Santeri Huvinen5,6 and Tuulikki Sokka-Isler7,8, 1University of Helsinki, Helsinki, Finland, 2Department of Internal Medicine, Päijät-Häme Central Hospital, Lahti, Finland, 3School of Medicine, University of Tampere, Tampere, Finland, 4Department of Rheumatology, Päijät-Häme Central Hospital, Lahti, Finland, 5Network of Academic Health Centres, Department of Medicine, University of Helsinki, Helsinki, Finland, 6FCG Finnish Consulting Group Ltd., Helsinki, Finland, 7Rheumatology, Jyvaskyla Central Hospital, Jyvaskyla, Finland, 8RAID working group for EULAR, Zurich, Switzerland

    Background/Purpose: Rheumatoid arthritis (RA) is associated with high healthcare costs, but little is known about how the costs compare to other chronic rheumatic diseases. We…
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