Abstract Number: 52 • 2019 ACR/ARP Annual Meeting
Autophagy Protein Microtubule-associated Protein 1 Light chain-3B (LC3B) Regulates Joint Inflammation and Destruction in Rheumatoid Arthritis
Background/Purpose: Here, we assumed that intracellular autophagy mechanism and its protein microtubule-associated protein 1 light chain-3B (LC3B) play an important role in the synovial fibroblasts…Abstract Number: 1949 • 2019 ACR/ARP Annual Meeting
The p.R321C Mutation in P62 Associated with Paget’s Disease of Bone Leads to a Change of Localization of the Protein in Human Osteoclasts
Background/Purpose: Paget´s disease of bone (PDB) is a chronic bone metabolic disorder. Currently, PDB is a focal disorder characterized by an increase in bone turnover…Abstract Number: 8 • 2015 ACR/ARHP Annual Meeting
Bay 11-7085 Induces Glucocorticoid Receptor Activation and Autophagy to Initiate Human Synovial Fibroblast Cell Death
Background/Purpose: BAY 11-7085 is an inhibitor of IκBα phosphorylation that leads to NF-κB inactivation and downregulation of inflammation in mouse model of asthma, in articular…