ACR Meeting Abstracts

ACR Meeting Abstracts

  • Meetings
    • ACR Convergence 2024
    • ACR Convergence 2023
    • 2023 ACR/ARP PRSYM
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • ACR Meetings

Abstracts tagged "Autoinflammatory Disease"

  • Abstract Number: 1233 • 2014 ACR/ARHP Annual Meeting

    Tocilizumab (TCZ) in the Treatment of AA Amyloidosis in Patients with Familial Mediterranean Fever

    Huri Ozdogan, Serdal Ugurlu, Aysa Hacioglu, Yasaman Adibnia and Vedat Hamuryudan, Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey

    Background/Purpose: AA amyloidosis is the major long-term complication of various chronic inflammatory diseases like rheumatoid arthritis, ankylosing spondylitis, FMF and other autoinflammatory syndromes. Treatment of…
  • Abstract Number: 1232 • 2014 ACR/ARHP Annual Meeting

    Canakinumab Therapy in Patients with Familial Mediterranean Fever

    Serdal Ugurlu, Emire Seyahi, Gulen Hatemi, Aysa Hacioglu, Fatma Nihan Akkoc and Huri Ozdogan, Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey

    Background/Purpose: According to a recent pilot study Canakinumab reduced the frequency of attacks in 9 patients with Familial Mediterranean Fever (FMF) resistant to colchicine with no…
  • Abstract Number: 1231 • 2014 ACR/ARHP Annual Meeting

    Evidence Based Recommendations for Genetic Diagnosis of Familial Mediterranean Fever

    Gabriella Giancane1, Nienke ter Haar2, Nico Wulffraat3, Bas Vastert4, Karyl Barron5, Veronique Hentgen6, Tilmann Kallinich7, Huri Ozdogan8, Jordi Anton9, Paul Brogan10, Luca Cantarini11, Joost Frenkel4, Caroline Galeotti12, Marco Gattorno13, Gilles Grateau14, Michael Hofer15, Isabelle Kone-Paut16, J B. Kuemmerle-Deschner17, Helen Lachmann18, Anna Simon19, Brian Feldman20, Yosef Uziel21 and Seza Ozen22, 1Pediatric Immunology, UMC, Utrecht, Netherlands, Utrecht, Netherlands, 2Laboratory for Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands, 3Pediatric rheumatology, Wilhelmina Children's Hospital/ UMC Utrecht, Utrecht, Netherlands, 4University Medical Center Utrecht, Utrecht, Netherlands, 5NIH, Bethesda, MD, 6Versailles Hospital, Le Chesnay Cedex, France, 7Charite, University Medicine Berlin, Berlin, Germany, 8Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, 9Pediatric Rheumatology Unit. Hospital Sant Joan de Déu. Universitat de Barcelona, Barcelona, Spain, 10Rheumatology Unit, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom, 11University of Siena, Siena, Italy, 12Bicêtre Hospital, University of Paris SUD, Paris, France, 13Istituto Giannina Gaslini, Genova, Italy, 14Service De Médecine Interne, Hopital Tenon, Paris, France, 15Centre Multisite Romand de Rhumatologie Pediatrique, Lausanne, Switzerland, 16Department of Pediatric Rheumatology, Reference Centre for Autoinflammatory Disorders CEREMAI, Bicêtre Hospital, University of Paris SUD, Paris, France, 17Division of Pediatric Rheumatology, Department of Pediatrics, University Hospital Tuebingen, Tuebingen, Germany, 18UK National Amyloidosis Centre, University College London Medical School, London, United Kingdom, 19Radboudumc, Nijmegen, Netherlands, 20Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 21Tel-Aviv University, Sackler School of Medicine, Tel-Aviv, Israel, 22Deptartment. of Pediatric Rheumatology, Hacettepe University, Ankara, Turkey

    Background/Purpose: Familial Mediterranean Fever (FMF) is a disease that starts in childhood and can lead to significant morbidity. In 2013, an initiative called SHARE (Single…
  • Abstract Number: 1205 • 2013 ACR/ARHP Annual Meeting

    Effectiveness Of Canakinumab In a Cryopyrin-Associated Periodic Syndrome Cohort.A Single Center Experience

    Virginia Moreira-Navarrete1, Francisco Javier Toyos Saenz de Miera2, Carmen Vargas Lebrón3 and F. Navarro Sarabia4, 1Rheumatology, University Hospital Virgen Macarena, Sevilla, Spain, 2Hospital Virgen de la Macarena, Sevilla, Spain, 3Hospital Virgen Macarena, SEVILLA, Spain, 4Rheumatologist Service, Hospital Universitario Virgen Macarena, Sevilla, Spain

    Background/Purpose: Cryopyrin-associated periodic syndrome (CAPS) comprises a group of rare, but severe, autoinflammatory diseases, characterized by urticaria, periodic fever, central nervous system inflammation, arthropathy, and…
  • Abstract Number: 1206 • 2013 ACR/ARHP Annual Meeting

    Canakinumab Treatment Regimens In CAPS Patients

    Ferdinand Hofer1, Theresa Endres1, Birgit Kortus-Goetze2, Norbert Blank3, Elisabeth Weissbarth-Riedel4, Catharina Schuetz5, Tilmann Kallinich6, Karoline Krause7, Christoph Rietschel8, Gerd Horneff9 and Jasmin B. Kuemmerle-Deschner10, 1Department of Pediatrics, Division of Pediatric Rheumatology, University Hospital Tuebingen, Tuebingen, Germany, 2Klinik für Innere Medizin, Klinikum der Philipps-Universität Marburg, Marburg, Germany, 3University of Heidelberg, Heidelberg, Germany, 4Kinderrheumatologische Ambulanz, Universitätsklinikum Eppendorf, Hamburg, Germany, 5Klinik für Kinder und Jugendmedizin, Universitätsklinikum Ulm, Ulm, Germany, 6Charite, University Medicine Berlin, Berlin, Germany, 7Dept. of Dermatology and Allergy, Allergie-Centrum-Charité, Charité – Universitätsmedizin Berlin, Germany, Berlin, Germany, 8Kinder- und Jugendrheumatologie, Clementine-Kinderhospital, Frankfurt, Germany, 9Department of Pediatrics, Asklepios Klinik Sankt Augustin, Sankt Augustin, Germany, 10University Hospital Tuebingen, Tuebingen, Germany

    Background/Purpose: Canakinumab is a recombinant monoclonal fully human antibody against Interleukin-1β and approved for the treatment of CAPS in many countries including Europe and the…
  • Abstract Number: 1213 • 2013 ACR/ARHP Annual Meeting

    Low-Penetrance NLRP3-Variants

    Theresa Endres1, Ferdinand Hofer1, Raphaela T. Goldbach-Mansky2, Hal M. Hoffman3, Norbert Blank4, Karoline Krause5, Christoph Rietschel6, Gerd Horneff7, Peter Lohse8 and Jasmin B. Kuemmerle-Deschner9, 1Department of Pediatrics, Division of Pediatric Rheumatology, University Hospital Tuebingen, Tuebingen, Germany, 2Translational Autoinflammatory Diseases Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD, 3Division of Allergy, Immunology and Rheumatology, University of California at San Diego, La Jolla, CA, 4University of Heidelberg, Heidelberg, Germany, 5Dept. of Dermatology and Allergy, Allergie-Centrum-Charité, Charité – Universitätsmedizin Berlin, Germany, Berlin, Germany, 6Kinder- und Jugendrheumatologie, Clementine-Kinderhospital, Frankfurt, Germany, 7Department of Pediatrics, Asklepios Klinik Sankt Augustin, Sankt Augustin, Germany, 8Institut für Laboratoriumsmedizin und Humangenetik, Singen, Germany, 9University Hospital Tuebingen, Tuebingen, Germany

    Background/Purpose: Cryopyrin-associated periodic syndrome (CAPS) presents as rare, autosomal dominant disease spectrum, due to mutations in the NLRP3-gene which lead to excessive interleukin-1 (IL-1) release.…
  • Abstract Number: 1167 • 2013 ACR/ARHP Annual Meeting

    A Possible Mechanism Of NLRP3 Inflammasome Hypersensitivity In Cryopyrin-Associated Periodic Syndrome

    Sayaka Ito, Chie Tagami, Yukichi Hara and Tetsuo Kubota, Tokyo Medical and Dental University, Tokyo, Japan

    Background/Purpose: NLRP3 in monocytes and other cell types plays a role in innate immunity as one of the intracellular pathogen recognition receptors, and its mutation…
  • Abstract Number: 2864 • 2013 ACR/ARHP Annual Meeting

    Whole Exome Sequencing In Pediatric Patients With Early Onset Rare Immunodysregulatory Diseases That Present With Fever and Systemic Inflammation

    Adriana Almeida de Jesus1, Julie Niemela2, Yin Liu3, Steven Boyden4, Ivona Aksentijevich5, Daniel L. Kastner6, Thomas A. Fleisher7, Raphaela Goldbach-Mansky3 and Zuoming Deng8, 1Translational Autoinflammatory Disease Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD, 2Laboratory Medicine, NIH Clinical Center, Bethesda, MD, 3Translational Autoinflammatory Diseases Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD, 4National Human Genome Research Institute, NIH, Bethesda, MD, 5Inflammatory Disease Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 6Inflammatory Disease Section, National Human Genome Research Institute, Bethesda, MD, 7Laboratory Medicine, Laboratory Medicine, NIH Clinical Center, Bethesda, MD, 8Biodata Mining and Discovery Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD

    Background/Purpose: WES (Whole Exome Sequencing) has increasingly become the tool of choice in translational research, providing molecular diagnoses in Mendelian diseases and identifying important genes…
  • Abstract Number: 1143 • 2013 ACR/ARHP Annual Meeting

    Increased Frequency Of Pratroling Monocytes In Experimental Arthritis and Rheumatoid Arthritis Patients In Response To IL6-R Blockade

    Julie Quentin1, Jessy Presumey2, Florence Apparailly2, Yves-Marie Pers3, Pascale Louis Plence4 and Christian Jorgensen3, 1Inserm U844, Montpellier, France, 2U844, Inserm, Montpellier, France, 3Department of therapy & Immuno-Rhumatology, Inserm U844, CHU saint-Eloi, Université Montpellier 1, CHU Lapeyronie, Montpellier, France, 4INSERM U844 Montpellier, Montpellier, France

    Background/Purpose: Monocytes represent a heterogeneous circulating population of immune cells that play important roles in the inflammatory response. Two main functional subsets of human monocytes…
  • Abstract Number: 2747 • 2013 ACR/ARHP Annual Meeting

    Canakinumab Treatment In Schnitzler’s Syndrome: A Multi-Center Randomized Placebo-Controlled 4-Month Study

    Karoline Krause, Karsten Weller, Martin Metz and Marcus Maurer, Dept. of Dermatology and Allergy, Allergie-Centrum-Charité, Charité – Universitätsmedizin Berlin, Germany, Berlin, Germany

    Background/Purpose: Schnitzler’s syndrome (SchS) is an adult-onset autoinflammatory disease characterized by urticarial exanthema and monoclonal gammopathy in combination with episodes of fever, arthralgia, fatigue, and…
  • Abstract Number: 227 • 2013 ACR/ARHP Annual Meeting

    Quantitative Image Analysis Of Articular Involvement In Blau Syndrome By Radiographic Calpal Length and Ultrasound Assessment

    Tsuyoshi Yamatou1, Tomohiro Kubota2, Harumi Akaike1, Yuichi Yamasaki2, Yukiko Nonaka1, Yasuhito Nerome1, Tomoko Takezaki1, Hiroyuki Imanaka1, Kei Ikeda3, Naotomo Kambe4, Syuji Takei5 and Tomokazu Nagakura6, 1Department of Pediatrics, Kagoshima University Hospital, Kagoshima, Japan, 2Dept of Pediatrics, Faculty of Medicine, Kagoshima University, Kagoshima, Japan, 3Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan, 4Dermatology, Chiba University Graduate School of Medicine, Chiba, Japan, 5School of Health Sciences, Faculty of Medicine, Kagoshima University, Kagoshima, Japan, 6Department of Pediatrics, House of Meguminoseibo, Usuki, Japan

    Background/Purpose: Blau syndrome (Blau) is a rare auto-inflammatory disease, and it has now been shown to be caused by NOD2/CARD15 gene mutations. Clinical features of…
  • Abstract Number: 2750 • 2013 ACR/ARHP Annual Meeting

    Long-Term Efficacy and Safety Of IL1 Receptor Antagonist In Schnitzler’s Syndrome : A French Multicenter Study

    Antoine Néel1, Agathe Masseau1, Sebastien Barbarot2, Benoit Henry3, Pierre-Jean Weiller4, Olivier Decaux5, Xavier Kyndt6, Xavier Puechal7, Arnaud Hot8, Pierre Pottier1, Amar Smail9, David Launay10, Jean-Marie Berthelot11, Eric Hachulla12, Leonardo Astudillo13, Pierre-Yves Hatron12, Laurent Sailler13, Aurelien Lorleac'h14, Achille Aouba15, Bérangère Cador16, Renato Fior17, Robin Dhote18, Fabrice Bonnet19, Jean-Dominique de Korwin20 and Mohamed Hamidou1, 1Internal Medicine Department, Nantes University Hospital, Nantes, France, 2Dermatology, Nantes University Hospital, Nantes, France, 3Infectious and Tropical Diseases, Pitié-Salpêtrière University Hospital, Paris, France, 4Internal Medicine Department, La Timone University Hospital, Marseille, France, 5Department of Internal Medicine, Rennes University Hospital, Rennes, France, 6Department of Nephrology and Internal Medicine, CH, Valenciennes, Valenciennes, France, 7Internal Medicine, Hôpital Cochin, Paris, France, 8Internal Medicine, Edouard Herriot University Hospital, Lyon, France, 9Internal Medicine Department, CHU Amiens Nord, Amiens, France, 10Internal Medicine, Claude Huriez University Hospital, Lille, France, 11Rheumatology Unit, Nantes University Hospital, Nantes, France, 12Department of Internal Medicine, Claude Huriez University Hospital, Lille, France, 13Department of Internal Medicine, Toulouse University Hospital, Toulouse, France, 14Internal Medicine Department, Lorient Hospital, Lorient, France, 15Hematology, Necker University Hospital, Paris, France, 16Internal Medicine Department, Rennes University Hospital, Rennes, France, 17Internal Medicine Department, Antoine Béclère University Hospital, Clamart, France, 18Internal Medicine, Avicenne University Hospital, Bobigny, France, 19Internal Medicine, Bordeaux University Hospital, Bordeaux, France, 20Internal Medicine Department, Nancy University Hospital, Nancy, France

    Background/Purpose: Schnitzler's syndrome is a rare late onset auto-inflammatory disease which associates a chronic/recurrent urticarial skin rash, a monoclonal gammopathy (mostly IgM kappa), and a…
  • Abstract Number: 2613 • 2013 ACR/ARHP Annual Meeting

    NF-κB Pathway Is Depleted In Phagocytes From Behçet´s Disease Patients Secondarily To Constitutive Phosphorylation Of The p65 Subunit

    Sandro F. Perazzio1,2, Paulo Vitor Soeiro Pereira3, Alexandre W.S. Souza4,5, Antonio Condino-Neto3 and Luis Eduardo C. Andrade6, 1Rheumatology, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil, 2Fleury Medicine and Health, Sao Paulo, Brazil, 3Immunology, ICB IV - Universidade de São Paulo, São Paulo, Brazil, 4University Medical Center Groningen, Groningen, Netherlands, 5Rheumatology Div/Dept of Med, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil, 6Rheumatology Division, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil

    Background/Purpose: : Increased neutrophil activation has been previously shown in Behçet’s disease (BD) patients and it is unclear whether neutrophil activation occurs constitutively or if…
  • Abstract Number: 2614 • 2013 ACR/ARHP Annual Meeting

    Plasma Of Active Behçet´s Disease Increases Oxidative Metabolism Profile Of Normal and Patients Phagocytes

    Sandro F. Perazzio1,2, Paulo Vitor Soeiro Pereira3, Alexandre W.S. Souza4,5, Antonio Condino-Neto3 and Luis Eduardo C. Andrade6, 1Rheumatology, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil, 2Fleury Medicine and Health, Sao Paulo, Brazil, 3Immunology, ICB IV - Universidade de São Paulo, São Paulo, Brazil, 4University Medical Center Groningen, Groningen, Netherlands, 5Rheumatology Div/Dept of Med, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil, 6Rheumatology Division, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil

    Background/Purpose: Behçet’s disease (BD) exhibits several features suggestive of neutrophil hiperactivity. It is unclear whether neutrophil activation occurs constitutively or if it is secondary to…
  • Abstract Number: 2173 • 2013 ACR/ARHP Annual Meeting

    The Interleukin-1 Receptor Antagonist Anakinra Is Effective In The Treatment Of Undifferentiated Periodic Fever Syndromes

    Daniella M. Schwartz1, Runsheng Wang2, Karyl Barron3, Daniel L. Kastner4 and Amanda K. Ombrello5, 1Rheumatology fellowship and training branch, National Institutes of Health, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, 2NIH/NIAMS, Rheumatology fellowship and training branch, Bethesda, MD, 3Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 4Inflammatory Disease Section, National Human Genome Research Institute, Bethesda, MD, 5National Human Genome Research Institute,National Institute of Health, Bethesda, MD

    Background/Purpose: The autoinflammatory diseases are a group of disorders associated with dysregulation of the innate immune system. They are characterized by recurrent episodes of fever…
  • « Previous Page
  • 1
  • …
  • 5
  • 6
  • 7
  • 8
  • Next Page »
Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

ACR Abstract Embargo Policy

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying financial and other sponsors about this policy. If you have questions about the abstract embargo policy, please contact the public relations department at [email protected].

Copyright Policy

View ACR Policies.

Wiley

  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences

© Copyright 2025 American College of Rheumatology