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Abstracts tagged "autoimmunity and rheumatoid arthritis (RA)"

  • Abstract Number: 3155 • ACR/ARHP Annual Meeting 2015

    Bob1 Expression Is Elevated in Rheumatoid Synovium and Its Expression in B Cells Is Required for Development of Collagen-Induced Arthritis

    Maartje Levels1,2,3, Melissa van Tok2,3,4, Tineke Cantaert2,3, Frans G.M. Kroese5, Hergen Spits6, Dominique Baeten2,3,4 and Nataliya Yeremenko1,2,3, 1Amsterdam Rheumatology and immunology Center, Amsterdam, Netherlands, 2Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, 3Laboratory of Experimental Immunology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, 4Amsterdam Rheumatology and Immunology Center, Amsterdam, Netherlands, 5Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, 6Department of Cell Biology and Histology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands

    Background/Purpose: Rheumatoid arthritis (RA) is a prototypic autoimmune disease characterized by a prominent humoral autoimmunity. Of particular relevance is the local production of autoantibodies and…

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