Abstracts tagged "autoimmunity and fibroblasts"

Abstract Number: 10 • 2018 ACR/ARHP Annual Meeting
Fibroblast like Synoviocytes (FLS) Are Capable of Inducing Phenotypical Changes Including Class Switch Recombination (CSR) in Naive B Cells, but Additional Factors Are Required to Trigger Immunoglobulin Secretion
Dennis Bleck¹, Torsten Lowin², Matthias Schneider³ and Georg Pongratz⁴, ¹Rheumatology Policlinic & Hiller Research Unit, Medical Faculty, University Hospital, Heinrich-Heine University Duesseldorf, Duesseldorf, Germany, ²Department and Hiller Research Center for Rheumatology, University Hospital Duesseldorf, Duesseldorf, Germany, ³Department and Hiller Research Center for Rheumatology, Heinrich-Heine University, Duesseldorf, Germany, ⁴Dpt. of Rheumatology - Hiller Research Center Rheumatology, University Hospital Duesseldorf, Duesseldorf, Germany
Background/Purpose: Rheumatoid Arthritis (RA) is a disease characterized by chronic inflammation of the synovial tissue in joints. It is driven by highly activated B cells.…

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