Abstracts tagged "autoimmunity and epigenetics"

Abstract Number: 1099 • 2018 ACR/ARHP Annual Meeting
Ongoing DNA Damage, Chromatin Deregulation and Defective DNA Damage Response in Systemic Autoimmune Rheumatic Diseases
Maria Pappa¹, Nikolaos I. Vlachogiannis¹, Alexandra Argyriou¹, Vassilis L. Souliotis² and Petros Sfikakis³, ¹National Kapodistrian University of Athens Medical School, Athens, Greece, First Department of Propaedeutic and Internal Medicine & Rheumatology Unit, National Kapodistrian University of Athens Medical School, Athens, Greece, Athens, Greece, ²National Hellenic Research Foundation, Athens, Greece, Institute of Biology, Medicinal Chemistry and Biotechnology, National Hellenic Research Foundation, Athens, Greece, Athens, Greece, ³Rheumatology Unit, 1st Dept. of Propaedeutic Internal Medicine, Joint Academic Rheumatology Program, Athens University Medical School, Athens, Greece
Background/Purpose: Recent data highlight that patients with Systemic Lupus Erythematosus (SLE) have defects in two main DNA repair pathways, namely nucleotide excision repair (NER) and…

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