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Abstracts tagged "autoimmune diseases and spondylarthritis"

  • Abstract Number: 1911 • ACR/ARHP Annual Meeting 2017

    Impaired Control of Autoreactive T Cell Expansion Is Coupled with Type-1 Regulatory T Cell Deficiency in BALB/c ZAP70W163C Mutant Mice

    M. Arifur Rahman1, Daphne Montizaan2, Zaied Ahmed Bhuyan3, Linda Rehaume3 and Ranjeny Thomas4, 1The University of Queensland Diamantina Institute, The University of Queensland, Brisbane, Australia, 2The University of Groningen, Groningen, Netherlands, 3The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia, 4Dendright Pty Ltd, Brisbane, Australia

    Background/Purpose: In the context of reduced TCR signaling in the BALB/c ZAP70W163C mutant (SKG) mouse, development of arthritis, psoriasis-like skin inflammation and ileitis after intra-peritoneal…

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