Abstracts tagged "autoimmune diseases and mitochondria"

Abstract Number: 111 • 2019 ACR/ARP Annual Meeting
The Transcription Factor STAT3 Regulates Pathogenic Th17 Responses in Autoimmune Disease via Noncanonical Roles
Catherine Poholek¹, Itay Raphael ² and Mandy McGeachy ², ¹UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, ²University of Pittsburgh, Pittsburgh, PA
Background/Purpose: The Th17 lineage of CD4 T cells drives autoimmune diseases such as RA, SLE, IBD, and MS. The JAK2/STAT3 signaling pathway is required for…

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Abstracts tagged "autoimmune diseases and mitochondria"

The Transcription Factor STAT3 Regulates Pathogenic Th17 Responses in Autoimmune Disease via Noncanonical Roles