Abstracts tagged "autoimmune diseases and inflammation"

Abstract Number: 133 • 2018 ACR/ARHP Annual Meeting
GBR830, a True OX40 Antagonist Antibody with Potent Suppressive Effects on T Cell-Mediated Pathological Responses
Julie Macoin¹, Stanislas Blein¹, Thierry Monney¹, Pavankumar Sancheti², Venkateshwar Reddy³ and Jonathan Back¹, ¹Glenmark Pharmaceuticals SA, La Chaux-de-Fonds, Switzerland, ²Glenmark Pharmaceuticals Ltd, Mumbai, India, ³Glenmark Pharmaceuticals SA, Paramus, NJ
Background/Purpose: OX40 (TNFRSF4, CD134) is a costimulatory receptor member of the NGFR/TNFR superfamily expressed predominantly on activated T lymphocytes. Ligation of OX40 by its ligand…

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Abstracts tagged "autoimmune diseases and inflammation"

GBR830, a True OX40 Antagonist Antibody with Potent Suppressive Effects on T Cell-Mediated Pathological Responses