Abstracts tagged "autoantibodies and SMN"

Abstract Number: 403 • 2019 ACR/ARP Annual Meeting
Single-specificity Anti-SMN Autoantibodies Are Associated with a Novel Scleromyositis Overlap Syndrome
Alexandra Baril-Dionne ¹, Océane Landon-Cardinal², Alain Meyer ³, Josiane Bourre-Tessier ¹, Yves Troyanov ⁴, Anne-Marie Mansour ⁵, Farah Zarka ⁵, Jean-Paul Makhzoum ⁶, Jessica Nehme ⁵, Eric Rich ¹, Jean-Richard Goulet ¹, Tamara Grodzicky ¹, Isabelle Richard ⁷, Marie Hudson ⁸, Valérie Leclair ⁹, Ira Targoff ¹⁰, Minoru Satoh ¹¹, Marvin Fritzler ¹² and Jean-Luc Senecal ¹, ¹Centre hospitalier de l'Universite de Montreal, Montreal, QC, Canada, ²Division of Rheumatology, Centre hospitalier de l'Université de Montréal; Department of Medicine, Université de Montréal, Montreal, QC, Canada, ³Centre de Reference des Maladies Autoimmunes Rares, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, ⁴Division of Rheumatology, Department of Medicine, Hôpital du Sacre-Coeur de Montreal, Montreal, QC, Canada, ⁵Hôpital du Sacre-Coeur de Montreal, Montreal, QC, Canada, ⁶Vasculitis Clinic, Hopital du Sacre-Coeur de Montreal, Montreal, QC, Canada, ⁷CISSS AT Rouyn-Noranda, Rouyn-Noranda, QC, Canada, ⁸Jewish General Hospital, Lady Davis Institute for Medical Research, and Department of Medicine, McGill University, Montreal, QC, Canada, ⁹Division of Rheumatology, Department of Medicine, Jewish General Hospital; Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Montreal, QC, Canada, ¹⁰University of Oklahoma Health Sciences Center, Oklahoma City, OK, ¹¹Department of Clinical Nursing, School of Health Sciences, University of Occupational and Environmental Health, Kitakyushu, Japan, ¹²Cumming School of Medicine, University of Calgary, Calgary, AB, Canada
Background/Purpose: Autoantibodies (aAbs) to proteins comprising the survival of motor neuron (SMN) macromolecular complex have not been thoroughly studied. Only two publications described clinical associations…