Abstracts tagged "autoantibodies and signal transduction"

Abstract Number: 3112 • 2016 ACR/ARHP Annual Meeting
DOCK8 Associates with STAT5 and Promotes Regulatory T Cell Function
Erin Janssen¹, Mira Tohme¹, Sumana Ullas² and Raif Geha², ¹Immunology, Boston Children's Hospital, Boston, MA, ²Boston Children's Hospital, Boston, MA
Background/Purpose: DOCK8 deficiency leads to autosomal recessive Hyper-IgE syndrome (AR-HIES). DOCK8 deficient patients develop recurrent sinopulmonary infections, chronic mucocutaneous viral infections, hyper-IgE, eosinophilia, food allergies,…

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Abstracts tagged "autoantibodies and signal transduction"

DOCK8 Associates with STAT5 and Promotes Regulatory T Cell Function