Abstracts tagged "autoantibodies and proteomics"

Abstract Number: 27 • 2018 ACR/ARHP Annual Meeting
Top-Down Proteomics Coupled with Antibody Sequencing from Single B Cells Reveals a Monoclonal Anti-Sm Clone Present in the Serum of an SLE Patient over Three Years
Zhe Wang¹, Jennifer Muther², Judith A. James³, Si Wu¹ and Kenneth Smith², ¹Chemistry and Biochemistry, University of Oklahoma, Norman, OK, ²Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ³University of Oklahoma Health Sciences Center, Oklahoma City, OK
Background/Purpose: Proteomics is becoming an increasingly powerful tool to study autoantibodies. Current bottom-up approaches are yielding a plethora of knowledge about public clonotypes and clonal…
Abstract Number: 1519 • 2012 ACR/ARHP Annual Meeting
Heterogeneous Nuclear RNP-K Is a Novel Cold-Related Autoantigen in Patients with Raynaud’s Phenomenon
Satoshi Serada¹, Minoru Fujimoto² and Tetsuji Naka², ¹Laboratory for immune signal, National Institute of Biomedical Innovation, Laboratory for immune signal, Japan, Ibaraki, Japan, ²Laboratory for immune signal, National Institute of Biomedical Innovation, Ibaraki, Japan
Background/Purpose: Raynaud’s phenomenon (RP) is a vasospastic disorder and shows discoloration of the fingers, toes, and occasionally other areas. RP affects 3-9% of the general…