Abstracts tagged "autoantibodies and genomics"

Abstract Number: 2672 • 2012 ACR/ARHP Annual Meeting
Genome-Wide Association Analysis Reveals Genetic Heterogeneity of Sjögren’s Syndrome (SS) According to Specific Subphenotypes and Ancestry
Lindsey A. Criswell¹, Kimberly E. Taylor², Caitlin McHugh³, Cathy Laurie³, Kimberly Doheny⁴, Mi Y. Lam², Joanne Nititham⁵, Laura Bierut⁶, Emily L. Harris⁷, Alan N. Baer⁸, Stephen Challacombe⁹, Yi Dong¹⁰, Hector Lanfranchi¹¹, Morten Schiodt¹², M. Srinivasan¹³, Susumu Sugai¹⁴, Hisanori Umehara¹⁵, Frederick B. Vivino¹⁶, Zhao Yan¹⁷, Stephen Shiboski², Troy Daniels¹⁸, John S. Greenspan¹⁹, Caroline Shiboski¹⁹ and SICCA²⁰, ¹Rosalind Russell Medical Research Center for Arthritis, Department of Medicine, Division of Rheumatology, University of California, San Francisco, San Francisco, CA, ²University of California, San Francisco, San Francisco, CA, ³University of Washington, Biostatistics, Seattle, WA, ⁴Center for Inherited Disease Research, Baltimore, MD, ⁵Medicine, Rosalind Russell Medical Research Center for Arthritis, San Francisco, CA, ⁶Psychiatry, Washington University, St. Louis, MO, ⁷National Institute of Dental and Craniofacial Research, Bethesda, MD, ⁸Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁹Kings College London, London, United Kingdom, ¹⁰Dept of Rheumatology, Peking Univ Med Coll Hospital, East City Beijing, China, ¹¹University of Buenos Aires, Buenos Aires, Argentina, ¹²Righospitalet, Copenhagen, Denmark, ¹³Aravind Eye Hospital, Madurai, India, ¹⁴Kanazawa Medical University, Ishikawa, Japan, ¹⁵Internal Medicine, Division of Hematology and Immunology, Kanazawa Medical University, Kanazawa, Japan, ¹⁶Medicine, Penn Presbyt Med Ctr, Philadelphia, PA, ¹⁷Department of Rheumatology, Peking Union Medical College Hospital, Beijing, China, ¹⁸Orofacial Sciences, Box 0422, UCSF Schools of Medicine & Dentistry, San Francisco, CA, ¹⁹Orofacial Sciences, University of California, San Francisco, San Francisco, CA, ²⁰San Francisco, CA
Background/Purpose: Our goal is to define the contribution of genetic factors to SS and related subphenotypes. Methods: We studied 2,459 participants in the Sjögren’s International…