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Abstracts tagged "autoantibodies and biomarkers"

  • Abstract Number: 722 • ACR/ARHP Annual Meeting 2017

    Differential Diagnosis of Autoimmune Diseases, Outlier Detection Plus Subgrouping in Clinical Trials By High Content Autoantibody Profiling

    Peter Schulz-Knappe, Petra Budde and Hans-Dieter Zucht, Protagen AG, Dortmund, Germany

    Background/Purpose: Early diagnosis as well as initiation of successful treatment are two big challenges in the management of patients with autoimmune diseases (AID). Overlap of…
  • Abstract Number: 1669 • ACR/ARHP Annual Meeting 2017

    Anti-Mitochondria DNA Antibody As an Improved Biomarker for Systemic Lupus Erythematosus

    Yangsheng Yu1, Kalika Mahato1, Suyang Xu1, Jenna Mu1, Amanda Zhang1, James R. O'Dell2, Lynell W. Klassen2, Michelene Hearth-Holmes3 and Kaihong Su1, 1Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, 2Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, 3Internal Medicine/Rheumatology Division, Univ. of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Anti-dsDNA antibodies are highly specific for systemic lupus erythematosus (SLE) and often associate with lupus nephritis. Extracellular nucleosome DNA released from apoptotic or necrotic…
  • Abstract Number: 786 • ACR/ARHP Annual Meeting 2013

    Antibodies Against Drp-4 and Macropain Subunit C2 As a Potential Marker Of Aosd

    Niklas T. Baerlecken1, Nils Pursche2, Torsten Witte3, Reinhold E. Schmidt1, Marius Hoepfner1, Frank Moosig4, Wolfgang L. Gross5, Eugen Feist6 and Dirk Foell7, 1Clinical Immunology and Rheumatology, Medical University Hannover, Hannover, Germany, 2Clinical Immunology and Rheumatology, Medical University of Hannover, Hannover, Germany, 3Clinical Immunology and Rheumatology, Medical University Hannover, Hanover, Germany, 4Vasculitis Clinic, Klinikum Bad Bramstedt & University Hospital of Schleswig Holstein, Bad Bramstedt, Germany, 5Dept of Clinical Rheumatology, Medical University at Lubeck, Lubeck, Germany, 6Department of Rheumatology and Clinical Immunology, Charité University Medicine, Berlin, Germany, 7Department of Pediatric Rheumatology and Immunology, University of Muenster, Muenster, Germany

    Background/Purpose: Making the diagnosis of adult-onset Still's disease (AOSD) is mainly based on the exclusion of inflammatory, infectious and malignant diseases. There are no specific…

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