Abstracts tagged "autoantibodies and bioinformatics"

Abstract Number: 1240 • 2015 ACR/ARHP Annual Meeting
Systematic Protein-Protein Interaction and Pathway Analyses in the Idiopathic Inflammatory Myopathies
Joanna Parkes¹, Simon Rothwell², Philip Day^1,3, Neil J McHugh⁴, Zoë Betteridge⁵, Robert Cooper⁶, William E. Ollier¹, Hector Chinoy², Janine Lamb⁷ and MYOGEN, ¹Centre for Epidemiology, University of Manchester, Manchester, United Kingdom, ²Centre for Musculoskeletal Research, University of Manchester, Manchester, United Kingdom, ³Manchester Institute of Biotechnology, University of Manchester, Manchester, United Kingdom, ⁴Rheumatology, Bath Institute of Rheumatic Diseases, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, ⁵Bath Institute of Rheumatic Diseases, Bath Institute of Rheumatic Diseases, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, ⁶MRC/ARUK Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, United Kingdom, ⁷Centre for Integrated Genomic Medical Research, University of Manchester, Manchester, United Kingdom
Background/Purpose: The idiopathic inflammatory myopathies (IIM) are autoimmune diseases characterised by acquired proximal muscle weakness, inflammatory cell infiltrates in muscle and myositis-specific/associated autoantibodies (MSA/MAA). The…

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