Abstract Number: 2871 • 2014 ACR/ARHP Annual Meeting
Break of Anergy in Human Autoreactive B Cells By T Helper Signals Restores B Cell Receptor Signaling Capacity and Is Dependent on Upregulation of CD45 Phosphatase Activity-a Possible Novel Mechanism of Breech of B Cell Tolerance in Rheumatic Diseases
Background/Purpose : We recently identified a human B cell population, which is naturally autoreactive and tolerized by functional anergy. This population was naïve, fully mature,…
ACR Meeting Abstracts