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Abstracts tagged "auto-immunity and rheumatoid arthritis"

  • Abstract Number: 414 • ACR/ARHP Annual Meeting 2012

    First-Degree Relatives without Rheumatoid Arthritis Exhibit Reactivity to Multiple Anti-Citrullinated Protein Antibodies in Association with Rheumatoid Arthritis-Related Clinical Characteristics: Studies of the Etiology of Rheumatoid Arthritis

    Kendra A. Young1, Kevin D. Deane2, Lezlie A. Derber3, Jan M. Hughes-Austin4, Michael H. Weisman5, Jane H. Buckner6, Ted R. Mikuls7, James R. O'Dell8, Richard M. Keating9, Peter K. Gregersen10, V. Michael Holers11 and Jill M. Norris1, 1Epidemiology, Colorado School of Public Health, Aurora, CO, 2Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, 3University of Colorado School of Medicine, Division of Rheumatology, Aurora, CO, 4Epidemiology, Colorado School of Public Health / University of Colorado Anschutz Medical Campus, Aurora, CO, 5Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, 6Benaroya Research Institute at Virginia Mason, Seattle, WA, 7Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, 8Dept of Internal Medicine, Univ of Nebraska Med Ctr, Omaha, NE, 9Rheumatology Section, The University of Chicago, Chicago, IL, 10Genomics and Human Genetics, Feinstein Institute for Medical Research, Manhasset, NY, 11Rheumatology Division, University of Colorado School of Medicine, Aurora, CO

    Background/Purpose: Prior to diagnosis of rheumatoid arthritis (RA), there are increases in the number of citrullinated proteins that anti-citrullinated protein antibodies (ACPA) target, suggesting an…

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