Abstracts tagged "auto-immunity and regulatory cells"

Abstract Number: 1123 • 2015 ACR/ARHP Annual Meeting
Regulatory B Cells Regulate Skin and Lung Fibrosis and Immunological Abnormalities in a Topoisomerase I and Complete Freund’s Adjuvant-Induced Scleroderma Model Via an Antigen-Specific Manner
Ayumi Yoshizaki¹, Takashi Taniguchi¹, Kouki Nakamura¹, Ryosuke Saigusa¹, Takashi Yamashita¹, Takehiro Takahashi¹, Tetsuo Toyama¹, Yohei Ichimura¹, Yoshihide Asano² and Shinichi Sato¹, ¹Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan, ²University of Tokyo Graduate School of Medicine, Tokyo, Japan
Background/Purpose: Immune cells play a critical role in systemic sclerosis (SSc). B cells have more functions than producing antibodies, including antigen-presentation, various cytokine production, and…
Abstract Number: 1746 • 2012 ACR/ARHP Annual Meeting
Semaphorin 3A Increases the Regulatory Characteristics of B-Regulatory Cells
Zahava Vadasz¹, Aharon Kessel² and Elias Toubi², ¹Clinical Immunology and Allergy, Bnai-Zion Medical Center, Haifa, Israel, ²Clinical Immunology and Allergy, Bnai-Zion Medical Center, Israel
Background/Purpose: Semaphorin3A (sem3A) and neuropilin-1 (NP-1), are important regulatory molecules, previously reported by us to play role in lupus glomerulonephritis. In a recent study we…

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