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Abstracts tagged "auto-immunity and citrullinated vimentin"

  • Abstract Number: 2615 • ACR/ARHP Annual Meeting 2012

    Circulating Levels of Citrullinated Vimentin Fragments Are Diagnostic and Prognostic in Ankylosing Spondylitis; Evidence for Disease-Related Citrullination

    Anne C. Bay-Jensen1, Morten Asser Karsdal2, Efstathios Vassiliadis3, Stephanie Wichuk4, Zheng Zhao5, Robert GW Lambert6, Rik Lories7, Claus Christiansen8 and Walter P. Maksymowych9, 1Cartilage Biomarkers and Research, Nordic Bioscience, Herlev, Denmark, 2Nordic Bioscience A/S, Herlev, Denmark, 3Nordic Bioscience, Herlev, Denmark, 4Medicine, University of Alberta, Edmonton, AB, Canada, 5Department of Rheumatology, University of Alberta and PLA General Hospital, Beijing, PR China, Beijing, AB, China, 6Radiology, University of Alberta, Edmonton, AB, Canada, 7Laboratory of Tissue Homeostasis and Disease - SBE Research Center, KU Leuven, Leuven, Belgium, 8CCBR, Ballerup, Denmark, 9Department of Medicine, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: Rheumatoid arthritis (RA) is considered an anti-CCP positive disease whereas ankylosing spondylitis (AS) is considered an anti-CCP negative disease. Anti-CCP has prognostic capacity in…

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