Abstracts tagged "Atherosclerosis"

Abstract Number: 677 • 2012 ACR/ARHP Annual Meeting
Antibodies to Oxidized Low Density Lipoprotein or Anti-Lipoprotein Lipase May Lead to More Atherosclerotic Plaque in a Sub-Set of SLE Patients
Biji T. Kurien¹, James Fesmire², Skyler P. Dillon³, Marianne Reichlin⁴, Morris Reichlin⁵ and Robert H. Scofield⁶, ¹College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ²Oklahoma Medical Research Foundation, ³Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, ⁴Oklahoma Medical Res Fndn, Oklahoma City, OK, ⁵Arthritis & Imm Laboratory, Oklahoma Medical Research Foun, Oklahoma City, OK, ⁶Arthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation; Department of Medicine, University of Oklahoma Health Sciences Center; US Department of Veterans Affairs Medical Center, Oklahoma City, OK
Background/Purpose: Premature atherosclerosis is associated with systemic lupus erythematosus (SLE). Oxidized low density lipoproteins (oxLDL) are important in atherosclerosis and have been reported in SLE…
Abstract Number: 1258 • 2012 ACR/ARHP Annual Meeting
Association Between Low Vitamin D Levels and Indicators of Osteoporosis and Atherosclerosis
Barry J. Sheane¹, Ruth Dunne², Ken Scott³, Mary Hall⁴, Michelle O'Connor², Martin Healy⁵, John Feely⁴, J.B. Walsh⁶ and Gaye Cunnane⁷, ¹Dept. of Rheumatology, St. James's Hospital, Dublin, Ireland, ²Diagnostic Imaging Department, St James's Hospital, Dublin, Ireland, ³Department of Pharmacology and Therapeutics, Trinity College Dublin, Dublin 8, Ireland, ⁴Department of Pharmacology and Therapeutics, St James's Hospital, Dublin, Ireland, ⁵Central Pathology Laboratory, St James's Hospital, Dublin, Ireland, ⁶Medicine for the Elderly, St James's Hospital, Dublin, Ireland, ⁷Dept of Rheumatology, St James's Hospital, Dublin, Ireland
Background/Purpose: Osteoporosis and cardiovascular disease are complications of chronic rheumatoid arthritis (RA). It is not known if these processes share pathogenetic mechanisms. Low levels of…
Abstract Number: 681 • 2012 ACR/ARHP Annual Meeting
Interferon Alpha Decreases Endothelial Nitric Oxide Synthase Function and Expression in Human Umbilical Vein Endothelial Cells
Joy Buie¹ and Jim Oates², ¹Rheumatology and Immunology, Medical University of South Carolina, Charleston, SC, ²Medicine, Medical University of South Carolina, Charleston, SC
Background/Purpose: Premenopausal SLE patients have a devastating increase in cardiovascular disease (CVD) and major associated cardiovascular events (MACE) that are not fully explained by Framingham…
Abstract Number: 1259 • 2012 ACR/ARHP Annual Meeting
Association Between Subclinical Atherosclerosis and Bone Mineral Density in Rheumatoid Arthritis
Barry J. Sheane¹, Ruth Dunne², Ken Scott³, Mary Hall⁴, Michelle O'Connor², Martin Healy⁵, John Feely⁴, J.B. Walsh⁶ and Gaye Cunnane⁷, ¹Rheumatology, St. James Hospital, Dublin, Ireland, ²Diagnostic Imaging Department, St James's Hospital, Dublin 8, Ireland, ³Department of Pharmacology and Therapeutics, Trinity College Dublin, Dublin 8, Ireland, ⁴Department of Pharmacology and Therapeutics, St James's Hospital, Dublin 8, Ireland, ⁵Central Pathology Laboratory, Dublin 8, Ireland, ⁶Medicine for the Elderly, Dublin 8, Ireland, ⁷Dept of Rheumatology, St James's Hospital, Dublin, Ireland
Background/Purpose: Rheumatoid arthritis (RA) is associated with a higher risk of osteoporosis (OP) and cardiovascular disease (CVD). This cross-sectional study was undertaken to identify links…
Abstract Number: 647 • 2012 ACR/ARHP Annual Meeting
Adjusted Framingham Risk Factor Scoring for Systemic Lupus Erythematosus: Results from an Inception Cohort Followed for Eight Years
Murray B. Urowitz¹, Dominique Ibanez¹, D. D. Gladman², SLICC³ and Systemic Lupus International Collaborating Clinics (SLICC)³, ¹Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ³Division of Rheumatology, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose : There is a high prevalence of premature atherosclerosis among patients with SLE, with a risk 7-9 times that of the general population. The…

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