Atherosclerosis and systemic lupus erythematosus (SLE) Archives

Abstract Number: 729 • ACR/ARHP Annual Meeting 2018
Atherosclerotic Vascular Events in SLE – an Evolving Story
Murray Urowitz¹, Jiandong Su¹ and Dafna D Gladman^1,2, ¹University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: Atherosclerotic vascular events (AVEs) are a major cause of mortality and morbidity in systemic lupus erythematosus (SLE) with a prevalence of 8-12%. We aimed…
Abstract Number: 730 • ACR/ARHP Annual Meeting 2018
Accrual of Atherosclerotic Vascular Events over 10 Years in a Multicentre Inception SLE Cohort
Murray Urowitz¹, Dafna D Gladman², Nicole Anderson² and Jiandong Su², ¹Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: The prevalence of atherosclerotic vascular events (AVE) in published literature of an inception cohort with SLE is 10%. We aimed to investigate the annual…
Abstract Number: 718 • ACR/ARHP Annual Meeting 2017
Atherosclerotic Vascular Events in a Multinational SLE Inception Cohort: Description and Predictive Risk Factors over a 17 Year Period
Murray Urowitz¹, Dafna D Gladman², Nicole Anderson³ and Jiandong Su⁴, ¹Centre for Prognosis Studies in the Rheumatic Diseases, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ³Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁴University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: A large multicentre multinational inception cohort was established to study risk factors for atherosclerosis (AS) in SLE. We aim to describe all vascular events…
Abstract Number: 1795 • ACR/ARHP Annual Meeting 2016
Four Years Follow-up of Subclinical Atherosclerosis in Systemic Lupus Erythematosus Patients
Ju-Yang Jung¹, Hyoun-Ah Kim¹ and Chang-Hee Suh², ¹Department of Rheumatology, Ajou University School of Medicine, Suwon, South Korea, ²Department of Rheumatology, Ajou University School of Medicine, Suwon, Korea, The Republic of
Background/Purpose: We assessed carotid artery intima-media thickness (cIMT) and carotid plaque by Doppler ultrasonography among sixty-one female SLE patients who were enrolled in the previous…
Abstract Number: 809 • ACR/ARHP Annual Meeting 2015
Patients with SLE Who Are Anti-Factor Xa IgG Positive Are Less Likely to Have Atherosclerotic Plaque
Claire-Louise Murphy¹, Sara Croca¹, Bahar Artim-Esen², Laura Hanns³, Charis Pericleous¹, Thomas McDonnell¹, Yiannis Ioannou⁴, David A. Isenberg¹, Anisur Rahman¹ and Ian Giles⁵, ¹Rayne Institute, Centre for Rheumatology Research, UCL Division of Medicine, London, United Kingdom, ²Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, ³Rheumatology, Arthritis Research UK Centre for Adolescent Rheumatology, UCL Division of Medicine, London, United Kingdom, ⁴Rayne Institute, Arthritis Research UK Centre for Adolescent Rheumatology, UCL Division of Medicine, London, United Kingdom, ⁵Rayne Intitiute, Centre for Rheumatology Research, UCL Division of Medicine, London, United Kingdom
Background/Purpose: Patients with SLE have an increased risk of cardiovascular disease (CVD), which is not fully explained by traditional risk factors and may be mediated…
Abstract Number: 3124 • ACR/ARHP Annual Meeting 2015
Associations of Circulating Cell-Free Micro-RNA with Vasculopathy and Vascular Events in SLE Patients
Susan Due Kay¹, Anting L. Carlsen², Anne Voss¹, Mikael Kjær Poulsen³, Axel Cosmus Pyndt Diederichsen⁴ and Niels H. H. Heegaard⁵, ¹Department of Rheumatology, Odense University Hospital, Odense C, Denmark, ²Department of Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark, ³Department of Cardiology, Odense University Hospital, Odense C, Denmark, ⁴Department of Cardiology,, Odense University Hospital, Odense C, Denmark, ⁵Department of Clinical Biochemistry & Pharmacology, Odense University Hospital, Odense C, Denmark
Background/Purpose: MicroRNAs (miRNAs) are small noncoding RNAs that modulate protein translation and regulate numerous immunologic and inflammatory pathways. Certain miRNA profiles have been associated with…
Abstract Number: 2255 • ACR/ARHP Annual Meeting 2012
Apolipoprotein B Containing Lipoprotein Subclasses and Subclinical Atherosclerosis in Patients with Systemic Lupus Erythematosus (SLE)
Adnan Kiani¹, Hong Fang¹, Ehtisham Akhter², Carmen Quiroga³, Nancy Simpson³, Petar Alaupovic³ and Michelle Petri¹, ¹Johns Hopkins University School of Medicine, Baltimore, MD, ²Div of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ³Oklahoma Medical Research Foundation, Oklahoma, OK
Background/Purpose: Traditional classification in lipid biology using HDL, LDL and VLDL does not provide information on lipoprotein function. Apolipoproteins, (which are protein components of plasma…
Abstract Number: 1706 • ACR/ARHP Annual Meeting 2012
Predictive Atherosclerotic Risk Factors At Inception in a Multicentre, Multinational Cohort
Murray B. Urowitz¹, Dominique Ibanez¹, D. D. Gladman² and SLICC³, ¹Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ³Toronto Western Hospital, Division of Rheumatology, Toronto, ON, Canada
Background/Purpose: Patients with systemic lupus erythematosus (SLE) develop premature atherosclerosis (AS). This study examines predictive factors at inception for atherosclerotic vascular events (AVE) over…
Abstract Number: 1709 • ACR/ARHP Annual Meeting 2012
Biomarkers of Atherosclerosis Are Associated with Progression of Non-Cardiovascular Damage in Patients with SLE
Sarah J. Kim¹, Jennifer M. Grossman², Brian Skaggs³, Elaine Lourenco³, Lori Sahakian⁴, John FitzGerald⁵, Nagesh Ragavendra⁶, Christina Charles-Schoeman⁷, Alan H. Gorn⁸, Bevra H. Hahn⁸ and Maureen A. McMahon⁹, ¹UCLA David Geffen School of Medicine, Los Angeles, CA, ²Div of Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, ³Medicine/Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, ⁴Division of Rheumatology, Department of Medicine,, UCLA David Geffen School of Medicine, Los Angeles, CA, ⁵Medicine-Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, ⁶Radiology, UCLA David Geffen School of Medicine, Los Angeles, CA, ⁷University of California, Los Angeles, CA, ⁸Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, ⁹Division of Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA
Background/Purpose: Studies have shown that even after taking traditional cardiac risk factors into account, SLE patients have up to 50-fold higher risk of developing atherosclerotic…
Abstract Number: 648 • ACR/ARHP Annual Meeting 2012
Atherosclerotic Vascular Events in a Multinational Inception Cohort of Systemic Lupus Erythematosus: Incidence Over a Ten Year Period
D. D. Gladman¹, Dominique Ibanez², Murray B. Urowitz² and SLICC³, ¹Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ²Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Division of Rheumatology Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: A large multicentre multinational inception cohort was established to study risk factors for atherosclerosis (AS) in SLE. The purpose of this study was to…

Abstracts tagged "Atherosclerosis and systemic lupus erythematosus (SLE)"