Abstracts tagged "Atherosclerosis and rheumatoid arthritis (RA)"

Abstract Number: 35 • 2018 ACR/ARHP Annual Meeting
Arthritis and Atherosclerosis in KRN Ag7 Mice Involve Distinct Inflammatory Cell Populations and Are Independent of CCR2
Anna B Montgomery¹, Carla M. Cuda², Salina Dominguez², Maximilian Mayr³, Deborah R. Winter² and Harris Perlman³, ¹Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Department of Medicine Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Rheumatoid arthritis (RA) is an inflammatory disease of the joints associated with cardiovascular disease, which accounts for 40% of RA mortality. Macrophages are implicated…
Abstract Number: 2355 • 2017 ACR/ARHP Annual Meeting
Arterial Wave Reflection and Subclinical Atherosclerosis in Rheumatoid Arthritis
Sule Gunter¹, Chanel Robinson¹, Angela Woodiwiss¹, Gavin Norton¹, Hon-Chun Hsu¹, Ahmed Solomon², Linda Tsang³, Aletta Millen¹ and Patrick Dessein⁴, ¹Physiology, University of Witwatersrand, Johannesburg, South Africa, ²Rheumatology, University of Witwatersrand, Johannesburg, South Africa, ³Rheumatology, Universitair Ziekenhuis Brussel, Brussels, Belgium, ⁴Rheumatology, Vrije Universiteit Brussel and Universitair Ziekenhuis Brussel, Brussels, Belgium
Background/Purpose: Rheumatoid arthritis (RA) increases atherosclerotic cardiovascular disease risk. Wave reflection occurs at arterial branching points, which are particularly prone to atherosclerosis. We hypothesised that…
Abstract Number: 547 • 2015 ACR/ARHP Annual Meeting
Abatacept Does Not Improve Subclinical Atherosclerosis Despite Good Response in Rheumatoid Arthritis: A Cohort Study
Kensuke Kume¹, Kanzo Amano^1,2, Susumu Yamada¹, Toshikatsu Kanazawa³, Kazuhiko Hatta⁴, Kuniki Amano⁵ and Noriko Kuwaba⁶, ¹Rheumatology, Hiroshima Clinic, Hiroshima, Japan, ²rheumatology., hiroshima clinic, Hiroshima, Japan, ³rheumatology, hiroshima clinic, hiroshima, Japan, ⁴Rheumatology, Hatta Clinic, Kure, Japan, ⁵Rheumatology, Sky Clinic, Hiroshima, Japan, ⁶Medical Research, Sanki Clinical Link, Hiroshima, Japan
Background/Purpose: Abatacept (ABT) is very effective in treating rheumatoid arthritis(RA)1. Patients with RA have an increased risk of cardiovascular disease (CVD), and rheumatologists need to…
Abstract Number: 2554 • 2015 ACR/ARHP Annual Meeting
Inhibition of IL6 Receptor Improves Arthritis and Atherosclerosis in a Mouse Model of Rheumatoid Arthritis
Amy Archer¹, Carla Cuda², Alexander Shaffer², Emily Alex Waters³, Chad Haney⁴, Rana Saber², George Kenneth Haines III⁵, Jason Low⁶ and Harris R. Perlman⁷, ¹Rheumatology, Northwestern University, Chicago, IL, ²Northwestern University, Chicago, IL, ³Chemistry of Life Processes Institute, Northwestern University, Evanston, IL, ⁴Center for Advanced Molecular Imaging, Northwestern University, Evanston, IL, ⁵Mount Sinai, New York, NY, ⁶Genentech, San Francisco, CA, ⁷Feinberg School of Medicine, Northwestern University, Chicago, IL
Background/Purpose: Rheumatoid arthritis is a chronic, systemic, autoimmune disease associated with an increased risk of cardiovascular disease. However, it is unclear what role patients’ dyslipidemia…
Abstract Number: 2824 • 2013 ACR/ARHP Annual Meeting
Urinary Microalbumin Is Associated With Arterial Stiffness In Patients With Rheumatoid Arthritis
Karima Becetti¹, Annette M. Oeser², Joseph F. Solus³, Paolo Raggi⁴, C. Michael Stein⁵ and Cecilia P. Chung¹, ¹Medicine, Vanderbilt University, Nashville, TN, ²Vanderbilt University, Nashville, TN, ³Medicine, Vanderbilt Medical Center, Nashville, TN, ⁴University of Alberta, Edmonton, AB, Canada, ⁵School of Medicine, Division of Clinical Pharmacology, Vanderbilt Medical Center, Nashville, TN
Background/Purpose: Rheumatoid arthritis (RA) is associated with an increased risk for cardiovascular disease (CVD). Urinary microalbumin is a risk factor for CVD in the general…
Abstract Number: 1685 • 2012 ACR/ARHP Annual Meeting
Differential Impact of Cardiac Risk Factors On Coronary Plaque Presence and Features in Asymptomatic Patients with Rheumatoid Arthritis Compared to Controls
George A. Karpouzas¹, Jennifer Malpeso², Tae-Young Choi², Silvia Munoz¹ and Matthew Budoff², ¹Rheumatology, Harbor-UCLA, Torrance, CA, ²Cardiology, Harbor-UCLA Medical Center, Torrance, CA
Background/Purpose: Traditional cardiac risk factors (CRFs) associate with myocardial infarction (MI) risk in both Rheumatoid arthritis (RA) and the general population. Subclinical atherogenesis has been…
Abstract Number: 1341 • 2012 ACR/ARHP Annual Meeting
Beneficial Effect of Anti-TNF Therapy in the Lipoprotein Atherogenic Risk Profile in Comparison with DMARD Standard Therapy in RA Patients
Jaime Calvo-Alen¹, Ignacio Villa², Victor M. Martinez-Taboada³, Jose Luis Peña-Sagredo⁴, Mario Agudo⁴, Ana Carmen García⁵ and Juan Gomez-Gerique⁶, ¹Rheumatology, Hospital de Sierrallana. Torrelavega. Spain, Torrelavega, Spain, ²Rheumatology, Hospital Universitario Sierrallana, Torrelavega, Spain, ³Rheumatology, Hospital Universitario Marques de Valdecilla. IFIMAV, Santander, Spain, ⁴Rheumatology, Hospital Universitario Marqués de Valdecilla. IFIMAV, Santander, Spain, ⁵Fundación 12 de Octubre, Madrid, Spain, ⁶Laboratorio de metabolismo lípidico y riesgo vascular, Hospital Universitario Marqués de Valdecilla, Santander, Spain
Background/Purpose: RA patients portend a greater risk of cardio-vascular complications than general population. Although most probably diverse mechanisms are implicated, quantity and quality changes in…
Abstract Number: 1251 • 2012 ACR/ARHP Annual Meeting
Vulnerability Features Are Common in Coronary Plaques of Asymptomatic Patients with Rheumatoid Arthritis Compared to Controls: Associations with Lipid and Oxidative Stress Biomarkers
George A. Karpouzas¹, Jennifer Malpeso², Tae-Young Choi², Silvia Munoz¹ and Matthew Budoff², ¹Rheumatology, Harbor-UCLA, Torrance, CA, ²Cardiology, Harbor-UCLA Medical Center, Torrance, CA
Background/Purpose: Computed tomography angiography (CTA) reliably evaluates coronary plaque presence, severity, burden, and composition. CT characteristics of culprit lesions in acute coronary syndromes (ACS) include…

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