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Abstracts tagged "atherosclerosis and epigenetics"

  • Abstract Number: 1636 • ACR/ARHP Annual Meeting 2013

    Pro-Inflammatory HDL and Subclinical Atherosclerosis Are Associated With Altered Expression Of Epigenetic and Oxidative Stress-Related Gene Transcripts In SLE

    Brian Skaggs1, Bevra H. Hahn2, Jennifer M. Grossman3, Elaine Lourenco1, Isao Matsuura4, Lori Sahakian5 and Maureen A. McMahon6, 1Medicine/Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, 2Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, 3Division of Rheumatology, Department of Medicine, UCLA David Geffen School of Medicine, Los Angeles, CA, 4UCLA David Geffen School of Medicine, Los Angeles, CA, 5Division of Rheumatology, Department of Medicine,, UCLA David Geffen School of Medicine, Los Angeles, CA, 6Division of Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA

    Background/Purpose: Premature atherosclerosis is widely recognized as a significant co-morbid condition of systemic lupus erythematosus (SLE), but exact mechanisms are unknown.  Although traditional cardiovascular risk…

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