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Abstracts tagged "atherosclerosis and autoimmunity"

  • Abstract Number: 2000 • 2015 ACR/ARHP Annual Meeting

    Immune Response Against  β2GPI Drives Th1 Inflammation in Atherosclerotic Plaques of Patients with Primary Antiphospholipid Syndrome

    Pier Luigi Meroni1,2, Marisa Benagiano3, Maria Gerosa4, Jacopo Romagnoli5, Michael Mahler6, Maria Orietta Borghi7,8, Alessia Grassi9, Chiara Della Bella3, Giacomo Emmi3, Amedeo Amedei3,10, Elena Silvestri3, Lorenzo Emmi11, Domenico Prisco9,10 and Mario Milco D'Elios3,10, 1Clinical Sciences and Community Heath, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy, 2Laboratory of Immuno-rheumatology, Laboratory of Immuno-rheumatology, IRCCS Istituto Auxologico Italiano, Cusano Milanino, Italy, 3Department of Experimental and Clinical Medicine, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy, 4Division of Rheumatology, Department of Clinical Sciences and Community Health, Ospedale Gaetano Pini, University of Milan, Milano, Italy, 5Department of Surgery, Department of Surgery, Catholic University of Rome, Rome, Italy, 6Inova Diagnostics, San Diego, CA, 7Department of Clinical Sciences and Community Health, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy, 8Laboratory of Immuno-rheumatology, IRCCS Istituto Auxologico Italiano, Milan, Italy, 9Department of Experimental and Clinical Medicine,, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy, 10Internal Interdisciplinary Medicine Center for Autoimmune Systemic Diseases, Lupus Clinic, Internal Interdisciplinary Medicine Center for Autoimmune Systemic Diseases, Lupus Clinic, AOU Careggi, Florence, Italy, 11Internal Interdisciplinary Medicine Center for Autoimmune Systemic Diseases, Lupus Clinic,, Internal Interdisciplinary Medicine Center for Autoimmune Systemic Diseases, Lupus Clinic, AOU Careggi, Florence, Italy

    Background/Purpose: Antiphospholipid syndrome (APS) is characterized by the presence of arterial and venous thrombosis, and by recurrent abortions, in patients with persistent presence of autoantibodies…
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