Abstracts tagged "atherosclerosis and autoimmunity"

Abstract Number: 2000 • 2015 ACR/ARHP Annual Meeting
Immune Response Against Â Î²2GPI Drives Th1 Inflammation in Atherosclerotic Plaques of Patients with Primary Antiphospholipid Syndrome
Pier Luigi Meroni^1,2, Marisa Benagiano³, Maria Gerosa⁴, Jacopo Romagnoli⁵, Michael Mahler⁶, Maria Orietta Borghi^7,8, Alessia Grassi⁹, Chiara Della Bella³, Giacomo Emmi³, Amedeo Amedei^3,10, Elena Silvestri³, Lorenzo Emmi¹¹, Domenico Prisco^9,10 and Mario Milco D'Elios^3,10, ¹Clinical Sciences and Community Heath, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy, ²Laboratory of Immuno-rheumatology, Laboratory of Immuno-rheumatology, IRCCS Istituto Auxologico Italiano, Cusano Milanino, Italy, ³Department of Experimental and Clinical Medicine, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy, ⁴Division of Rheumatology, Department of Clinical Sciences and Community Health, Ospedale Gaetano Pini, University of Milan, Milano, Italy, ⁵Department of Surgery, Department of Surgery, Catholic University of Rome, Rome, Italy, ⁶Inova Diagnostics, San Diego, CA, ⁷Department of Clinical Sciences and Community Health, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy, ⁸Laboratory of Immuno-rheumatology, IRCCS Istituto Auxologico Italiano, Milan, Italy, ⁹Department of Experimental and Clinical Medicine,, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy, ¹⁰Internal Interdisciplinary Medicine Center for Autoimmune Systemic Diseases, Lupus Clinic, Internal Interdisciplinary Medicine Center for Autoimmune Systemic Diseases, Lupus Clinic, AOU Careggi, Florence, Italy, ¹¹Internal Interdisciplinary Medicine Center for Autoimmune Systemic Diseases, Lupus Clinic,, Internal Interdisciplinary Medicine Center for Autoimmune Systemic Diseases, Lupus Clinic, AOU Careggi, Florence, Italy
Background/Purpose: Antiphospholipid syndrome (APS) is characterized by the presence of arterial and venous thrombosis, and by recurrent abortions, in patients with persistent presence of autoantibodies…