Abstract Number: 2067 • ACR Convergence 2026
A Novel Negative-Pressure Blind Synovial Biopsy Needle in 932 Patients: Diagnostic Spectrum, Tissue Quality, Molecular Compatibility, and Safety
Background/Purpose: Synovial biopsy is crucial for tissue-based diagnosis and disease stratification in arthritis. However, conventional blind biopsy is limited to the knee, whereas ultrasound-guided or…Abstract Number: 0840 • ACR Convergence 2022
Postoperative Risk of Immunosuppression in Rheumatic Disease Patients Undergoing Arthroscopy
Background/Purpose: Recent literature suggests that rheumatic disease patients hold most immunosuppressive (IS) medications before and after joint replacement surgery, to prevent infections and other complications.…Abstract Number: 0465 • ACR Convergence 2021
Cost-effectiveness of Treatment Strategies Involving Arthroscopic Partial Meniscectomy and Physical Therapy for Degenerative Meniscal Tear
Background/Purpose: Knee osteoarthritis (KOA) and meniscal tear (MT) are highly prevalent and often concomitant. Treatments for MT in the presence of KOA include physical therapy…Abstract Number: 1200 • ACR Convergence 2021
Predicting Progression to RA in Patients with Seropositive Arthralgia
Background/Purpose: Rheumatoid Arthritis (RA) is a chronic inflammatory condition often associated with joint destruction, disability, and reduced life expectancy. Before RA diagnosis, some patients may…Abstract Number: 1232 • ACR Convergence 2021
Synovial Tissue Lymphoid Aggregates Are Associated with Response to Rituximab Therapy in Rheumatoid Arthritis Patients
Background/Purpose: Activated B lymphocytes and plasma cells are implicated in the pathogenesis of rheumatoid arthritis (RA). The anti-CD20 monoclonal antibody therapy (Rituximab) is an effective…Abstract Number: 1608 • ACR Convergence 2020
Survey of Minimally-Invasive Ultrasound-Guided Synovial Biopsy Performed at Rheumatology Centres
Background/Purpose: Ultrasound-guided synovial biopsy (USGSBx) is a well-established minimally-invasive alternative to arthroscopy for sampling synovial tissue. Adverse event rates in published studies are favourable by…Abstract Number: 310 • ACR/ARHP Annual Meeting 2016
A Novel One Stage Technique Applicable during Arthroscopy for the Mobilization of Synovial Mesenchymal Stromal Cells Towards Joint Regeneration
Background/Purpose: , The discovery of MSCs in the synovium and synovial fluid (SF) provided a potential mechanism for repairing cartilage “from the top down”. Indeed,…Abstract Number: 2635 • ACR/ARHP Annual Meeting 2015
Validating Arthroscopic Findings Using Histology, Status for Erosive Disease, and CRP in RA
Background/Purpose: The utility of synovial biopsy has been confirmed as an important research tool in increasing our understanding of the pathogenesis of RA, evaluating new…Abstract Number: 995 • ACR/ARHP Annual Meeting 2015
In Rheumatoid Arthritis Only a Few Expanded T-Cell Clones Dominate in Joint Inflammation: A Study in Seven RA Patients Undergoing Paired Synovial Tissue Biopsies in Multiple Joints
Background/Purpose: Previously we found a strong enrichment of highly expanded T-cell clones in rheumatoid arthritis (RA) synovial tissue of inflamed joints. To gain more insight…Abstract Number: 2387 • ACR/ARHP Annual Meeting 2015
The Effect of Arthroscopic Partial Meniscectomy in Patients with Osteoarthritis on Meniscal Body Extrusion
Background/Purpose: Meniscal damage and extrusion are both strongly associated with the progression of knee OA. Concerns have recently been raised that arthroscopic partial meniscectomy (APM)…Abstract Number: 109 • ACR/ARHP Annual Meeting 2014
Knee Arthroscopy in an International Training Centre: An Audit of Safety and Impact on Work Days
Background/Purpose The utility of synovial biopsy has been confirmed as an important research tool in increasing our understanding of the pathogenesis of RA, evaluating new…Abstract Number: 81 • ACR/ARHP Annual Meeting 2013
Synovial Expression Of CCL19, MCP-1, and Their Receptors In Patients With Meniscal Injury: Variability and Relationship With Knee Symptoms
Background/Purpose: Patients with meniscal injury are at increased risk for symptomatic knee osteoarthritis (OA), and often already have intraoperative signs of early-stage cartilage degradation. We…Abstract Number: 2342 • ACR/ARHP Annual Meeting 2012
Synovial Tissue Analysis in the Pre-Clinical Phase of Arthritis: T-Cell Infiltration Preceding the Development of Arthritis
Background/Purpose: We have previously shown in a pilot study that there is no evident synovial inflammation in autoantibody-positive individuals who are at risk of developing…Abstract Number: 1191 • ACR/ARHP Annual Meeting 2012
Nicotinamide Adenine Dinucleotide Phosphate Oxidase Mediated Angiogenesis and Inflammation in the Arthritic Joint
Background/Purpose: To examine the role of Nicotinamide Adenine Dinucleotide Phosphate Oxidase (NADPH oxidase)-derived Reactive Oxygen Species (ROS) and NADPH oxidase-dependent redox signaling events in regulating…Abstract Number: 1 • ACR/ARHP Annual Meeting 2012
Evaluation of Synovial Inflammation Assessed by Macroscopic and Histological Criteria in Patients with Knee Osteoarthritis
Background/Purpose: Although osteoarthritis (OA) is commonly described as a non-inflammatory joint disease, synovial inflammation is increasingly recognized as contributing to the symptoms and progression of…
ACR Meeting Abstracts