ACR Meeting Abstracts

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Abstracts tagged "Arthroscopy"

  • Abstract Number: 0840 • ACR Convergence 2022

    Postoperative Risk of Immunosuppression in Rheumatic Disease Patients Undergoing Arthroscopy

    Kinjal Vasvada, Laith Jazrawi and Jonathan Samuels, NYU Langone Health, New York, NY

    Background/Purpose: Recent literature suggests that rheumatic disease patients hold most immunosuppressive (IS) medications before and after joint replacement surgery, to prevent infections and other complications.…
  • Abstract Number: 0465 • ACR Convergence 2021

    Cost-effectiveness of Treatment Strategies Involving Arthroscopic Partial Meniscectomy and Physical Therapy for Degenerative Meniscal Tear

    Emma Williams1, Valia Leifer1, Jamie Collins2, Tuhina Neogi3, Lisa Suter4, Jeffrey Katz5 and Elena Losina2, 1The Orthopaedic and Arthritis Center for Outcomes Research (OrACORe) at Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, MA, 3Boston University School of Medicine, Boston, MA, 4Yale School of Medicine, New Haven, CT, 5Brigham and Women's Hospital, Brookline, MA

    Background/Purpose: Knee osteoarthritis (KOA) and meniscal tear (MT) are highly prevalent and often concomitant. Treatments for MT in the presence of KOA include physical therapy…
  • Abstract Number: 1200 • ACR Convergence 2021

    Predicting Progression to RA in Patients with Seropositive Arthralgia

    Aine Gorman1, Keelin Flynn2, Matthew Turk1, Candice Low3, Kieran Murray4, Carl Orr5, Phil Gallagher5, Lorna Freeman2, Edel Meaney2, Eamonn Molloy6, Lorraine O Neill7, Ursula Fearon8 and Douglas Veale9, 1St Vincents Hospital, Dublin, Ireland, 2The Centre for Arthritis and Rheumatic Disease, EULAR Centre of Excellence, St. Vincent’s University Hospital and University College Dublin, Ireland, Dublin, Ireland, 3St. Vincent's University Hospital, Dublin, Ireland, 4Saint Vincent's University Hospital, Dublin, Ireland, 5St Vincent's Hospital, Dublin, Ireland, 6St Vincent's Healthcare Group, Dublin, Ireland, 7St. Vincent's Hospital, Dublin, Ireland, 8Trinity College Dublin, Dublin, Ireland, 9University College Dublin, Dublin, Ireland

    Background/Purpose: Rheumatoid Arthritis (RA) is a chronic inflammatory condition often associated with joint destruction, disability, and reduced life expectancy. Before RA diagnosis, some patients may…
  • Abstract Number: 1232 • ACR Convergence 2021

    Synovial Tissue Lymphoid Aggregates Are Associated with Response to Rituximab Therapy in Rheumatoid Arthritis Patients

    Matthew Turk1, Candice Low2, Carl Orr3, Richard Conway4, Kieran Murray5, Ursula Fearon6 and Douglas Veale7, 1St. Vincents University Hospital, Dublin, Ireland, 2St. Vincent's University Hospital, Dublin, Ireland, 3St Vincent's Hospital, Dublin, Ireland, 4St. James's University Hospital, Dublin, Ireland, 5Saint Vincent's University Hospital, Dublin, Ireland, 6Trinity College Dublin, Dublin, Ireland, 7University College Dublin, Dublin, Ireland

    Background/Purpose: Activated B lymphocytes and plasma cells are implicated in the pathogenesis of rheumatoid arthritis (RA). The anti-CD20 monoclonal antibody therapy (Rituximab) is an effective…
  • Abstract Number: 1608 • ACR Convergence 2020

    Survey of Minimally-Invasive Ultrasound-Guided Synovial Biopsy Performed at Rheumatology Centres

    Bernard Dyke1, Mark Maybury2, Stefano Alivernini3, Juan Cañete4, Orazio De Lucia5, João Eurico Fonseca6, Nicola Gullick7, Søren Just8, David Kane9, Juhani Koski10, Antonio Manzo11, Laurent Meric de Bellefon12, Ronan Mullan9, Aurelie Najm13, Arthur Pratt14, Felipe Julio Ramirez Garcia15, Charlotte Rawlings16, Fiona Rayner17, Vasco Romão18, Ilfita Sahbudin2, Darren Tabechian19 and Andrew Filer2, 1Institute of Inflammation and Ageing, University of Birmingham, Birmingham, England, United Kingdom, 2Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom, 3Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, 4Arthritis Unit, Rheumatology Dpt, Hospital Clinic, Barcelona, Spain and IDIBAPS, Barcelona, Spain, 5ASST Gaetano Pini-CTO Orthopedic and Traumatology Specialist Center, Milan, Italy, 6Instituto de Medicina Molecular, Faculdade Medicina Universidade de Lisboa and Centro Hospitalar Universitário Lisboa Norte., Lisboa, Portugal, 7University Hospital Coventry & Warwickshire, Knowle, United Kingdom, 8Svendborg Hospital - Odense University Hospital, Odense, Denmark, 9Tallaght University Hospital, Dublin, Ireland, 10Mikkeli Central Hospital, Mikkeli, Finland, 11IRCCS Policlinico San Matteo Foundation/University of Pavia, Pavia, Italy, 12Cliniques Universitaires Saint-Luc, Woluwe-Saint-Lambert, Belgium, Brussels, Belgium, 13Nantes University Hospital, Nantes, France, 14Newcastle University, Newcastle upon Tyne, United Kingdom, 15Arthritis Unit, Rheumatology Dpt, Hospital Clinic, Barcelona, Spain, Barcelona, Catalonia, Spain, 16Cardiff University School of Medicine, Cardiff, United Kingdom, 17Newcastle University, Newcastle, United Kingdom, 18Instituto de Medicina Molecular, Faculdade Medicina Universidade de Lisboa and Centro Hospitalar Universitário Lisboa Norte., Lisbon, Portugal, 19University of Rochester Medical Center, Rochester, NY

    Background/Purpose: Ultrasound-guided synovial biopsy (USGSBx) is a well-established minimally-invasive alternative to arthroscopy for sampling synovial tissue.  Adverse event rates in published studies are favourable by…
  • Abstract Number: 310 • 2016 ACR/ARHP Annual Meeting

    A Novel One Stage Technique Applicable during Arthroscopy for the Mobilization of Synovial Mesenchymal Stromal Cells Towards Joint Regeneration

    Alam Khalil-Khan1, Thomas Baboolal2, Elena Jones3, Owen Wall4 and Dennis McGonagle3, 1Faculty of Medicine, Leeds institute of Rheumatic and Musculoskeletal Medicine,, Leeds, United Kingdom, 2PhD, Leeds, United Kingdom, 3Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 4Orthopaedic Surgery, Department of Trauma and Orthopaedics, Leeds, United Kingdom

    Background/Purpose: , The discovery of MSCs in the synovium and synovial fluid (SF) provided a potential mechanism for repairing cartilage “from the top down”. Indeed,…
  • Abstract Number: 2635 • 2015 ACR/ARHP Annual Meeting

    Validating Arthroscopic Findings Using Histology, Status for Erosive Disease, and CRP in RA

    Carl Orr1, Trudy McGarry2, Francis Young3, Ursula Fearon2 and Douglas J. Veale1, 1St Vincent's University Hospital, Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre, Dublin 4, Ireland, 2St. Vincent's University Hospital, Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre, Dublin 4, Ireland, 3Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre, Dublin 4, Ireland

    Background/Purpose: The utility of synovial biopsy has been confirmed as an important research tool in increasing our understanding of the pathogenesis of RA, evaluating new…
  • Abstract Number: 995 • 2015 ACR/ARHP Annual Meeting

    In Rheumatoid Arthritis Only a Few Expanded T-Cell Clones Dominate in Joint Inflammation: A Study in Seven RA Patients Undergoing Paired Synovial Tissue Biopsies in Multiple Joints

    Anne Musters1, Paul L. Klarenbeek1,2, Marieke E. Doorenspleet1,2, Rebecca E.E. Esveldt1,2, Barbera D.C. van Schaik3, Sander W. Tas1,2, Antoine H.C. van Kampen3, Frank Baas4 and Niek de Vries1,2, 1Dept. of Clinical Immunology & Rheumatology, Amsterdam Rheumatology and immunology Center | Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, 2Dept. of Experimental Immunology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, 3Bioinformatics Laboratory, Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, 4Dept. of Genome Analysis, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands

    Background/Purpose: Previously we found a strong enrichment of highly expanded T-cell clones in rheumatoid arthritis (RA) synovial tissue of inflamed joints. To gain more insight…
  • Abstract Number: 2387 • 2015 ACR/ARHP Annual Meeting

    The Effect of Arthroscopic Partial Meniscectomy in Patients with Osteoarthritis on Meniscal Body Extrusion

    Martin Englund1,2, Fan Zhang3, Ali Guermazi4, Frank W Roemer5,6, Elena Losina7 and Jeffrey N. Katz8, 1Clinical Epidemiology Unit, Orthopedics, Dept of Clinical Sciences Lund, Lund University, Lund, Sweden, 2Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 3Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden, 4Boston University School of Medicine, Boston, MA, 5Department of Radiology, University of Erlangen-Nuremberg, Erlangen, Germany, 6Department of Radiology, Boston University School of Medicine, Boston, MA, 7Orthopaedics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 8Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: Meniscal damage and extrusion are both strongly associated with the progression of knee OA. Concerns have recently been raised that arthroscopic partial meniscectomy (APM)…
  • Abstract Number: 109 • 2014 ACR/ARHP Annual Meeting

    Knee Arthroscopy in an International Training Centre: An Audit of Safety and Impact on Work Days

    Carl Orr1, Paul MacMullan1, Phil Gallagher2, Mairead Murray1, Madeline O'Neill1 and Douglas J. Veale3, 1Rheumatology, Dublin Academic Medical Centre, St. Vincent's University Hospital, Dublin, Ireland, 2Rheumatology, St. Vincent's University Hospital, Dublin, Ireland, 3Translational Rheumatology Research Group, St. Vincent's University Hospital, Dublin 4, Ireland

    Background/Purpose The utility of synovial biopsy has been confirmed as an important research tool in increasing our understanding of the pathogenesis of RA, evaluating new…
  • Abstract Number: 81 • 2013 ACR/ARHP Annual Meeting

    Synovial Expression Of CCL19, MCP-1, and Their Receptors In Patients With Meniscal Injury: Variability and Relationship With Knee Symptoms

    Justin B. Gan1, Anjali Nair2, Kanta Saha1, Nikhil Verma3, Charles Bush-Joseph3, Matthew Tetreault3, Anne-Marie Malfait4, Kumar B. Rajan5 and Carla R. Scanzello1, 1Rheumatology, Rush University Medical Center, Chicago, IL, 2Section of Rheumatology, Rush University Medical Center, Chicago, IL, 3Orthopedics, Rush University Medical Center, Chicago, IL, 4Internal Medicine/Biochemistry, Rush University Medical Center, Chicago, IL, 5Department of Internal Medicine, Biostatistics, Rush University Medical Center, Chicago, IL

    Background/Purpose: Patients with meniscal injury are at increased risk for symptomatic knee osteoarthritis (OA), and often already have intraoperative signs of early-stage cartilage degradation. We…
  • Abstract Number: 2342 • 2012 ACR/ARHP Annual Meeting

    Synovial Tissue Analysis in the Pre-Clinical Phase of Arthritis: T-Cell Infiltration Preceding the Development of Arthritis

    Maria J. H. de Hair1, Marleen G. H. van de Sande1, Tamara H. Ramwadhdoebe2, Robert B. M. Landewé3, Christiaan van der Leij4, Mario Maas5, Dirkjan van Schaardenburg6, Danielle Marie Gerlag1, Lisa G.M. van Baarsen2 and Paul P. Tak7, 1Division of Clinical Immunology and Rheumatology, Academic Medical Center / University of Amsterdam, Amsterdam, Netherlands, 2Division of Clinical Immunology and Rheumatology and Department of Experimental Immunology , Academic Medical Center / University of Amsterdam, Amsterdam, Netherlands, 3Division of Clinical Immunology and Rheumatology, Academic Medical Center / University of Amsterdam & Atrium Medical Center, Amsterdam, Netherlands, 4Department of Radiology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, 5Department of Radiology, Academic Medical Center / University of Amsterdam, Amsterdam, Netherlands, 6Rheumatology, Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, 7Division of Clinical Immunology and Rheumatology, Academic Medical Center / University of Amsterdam and GlaxoSmithKline, Amsterdam, Netherlands

    Background/Purpose: We have previously shown in a pilot study that there is no evident synovial inflammation in autoantibody-positive individuals who are at risk of developing…
  • Abstract Number: 1191 • 2012 ACR/ARHP Annual Meeting

    Nicotinamide Adenine Dinucleotide Phosphate Oxidase Mediated Angiogenesis and Inflammation in the Arthritic Joint

    Monika Biniecka1, Wei Gao2, Chin Teck Ng1, Emese Balogh2, Douglas J. Veale2 and Ursula Fearon2, 1Rheumatology, Translation Research Group, Dublin Academic Medical Centre, St. Vincent's University Hospital, Dublin, Ireland, 2Dublin Academic Medical Centre, St. Vincent's University Hospital, Translation Rheumatology Research Group, Dublin, Ireland

    Background/Purpose: To examine the role of Nicotinamide Adenine Dinucleotide Phosphate Oxidase (NADPH oxidase)-derived Reactive Oxygen Species (ROS) and NADPH oxidase-dependent redox signaling events in regulating…
  • Abstract Number: 1 • 2012 ACR/ARHP Annual Meeting

    Evaluation of Synovial Inflammation Assessed by Macroscopic and Histological Criteria in Patients with Knee Osteoarthritis

    Montserrat Romera-Baures Sr.1, Ramon Valls-Garcia Sr.2, Antonio Rozadilla Sr.3, Marta Terricabras Sr.4 and Joan Miquel Nolla Sr.5, 1Rheumatology, Hospital Universitari Bellvitge, Barcelona, Spain, 2Rheumatology, Hospital de Palamos, Girona, Palamos (Girona), Spain, 3Rheumatology, Hospital Universitari de Bellvitge, Barcelona, Spain, 4Departament of Pathology, Hospital Universitari de Bellvitge., Barcelona, Spain, 5Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain

    Background/Purpose: Although osteoarthritis (OA) is commonly described as a non-inflammatory joint disease, synovial inflammation is increasingly recognized as contributing to the symptoms and progression of…
  • Abstract Number: 2650 • 2012 ACR/ARHP Annual Meeting

    The Meteor Trial: Preliminary Results of an RCT of Arthroscopic Partial Meniscectomy Vs. Physical Therapy in Patients greater Than 45

    Jeffrey N. Katz1, Christine E. Chaisson2, Brian Cole3, Laurel Donnell-Fink1, Morgan Jones4, Bruce Levy5, Lisa A. Mandl6, Scott Martin1, Robert Marx7, Anthony Miniaci8, Joseph Palmisano9, Emily Reinke10, Clare Safran-Norton1, Debra J. Skoniecki11, Daniel Solomon12, Kurt P. Spindler10, John Wright13, Rick Wright14 and Elena Losina15, 1Brigham and Women's Hospital, Boston, MA, 2Boston University School of Public Health, Boston, MA, 3Rush University, Chicago, IL, 4Orthopedic Surgery, Cleveland Clinic, Cleveland, OH, 5Orthopedics, Mayo Clinic, Rochester, MN, 6Rheumatology, Hospital for Special Surgery, New York, NY, 7Orthopedic Surgery, Hospital for Special Surgery, New York, NY, 8Orthopedics, Cleveland Clinic, Cleveland, OH, 9Boston University School of Public Health, 10Vanderbilt University, Nashville, TN, 11Brigham & Womens Hospital, Boston, MA, 12Division of Rheumatology, Brigham & Womens Hospital, Boston, MA, 13Orthopedic Surgery, Brigham and Women's Hospital, Boston, MA, 14Orthopedics, Washington University, Saint Louis, MO, 15Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Patients who present with a symptomatic knee that has both osteoarthritis and a meniscal tear present a difficult treatment challenge. They may be treated…
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