Abstracts tagged "Arthritis, Infectious"

Abstract Number: 2576 • ACR Convergence 2025
Methotrexate Treatment of Arthritis Caused by Chikungunya Virus (MARCH) Study: Anti-inflammatory cytokine signals related to decreased arthritis disease activity over time
Alfonso Sucerquia¹, Jose Forero², Juan Alzate¹, Adrienne Poon³, Gary Firestein⁴, Larry Moreland⁵, Andres Cadena⁶, Jose Lara⁶, Octavio pizarro⁶, Jesus Godoy⁶, Liliana Encinales⁷, David Boyle⁸, Evelyn Mendoza⁹, Carlos Herrera¹⁰ and Aileen Chang³, ¹The George Washington University, Arlington, ²The George Washington University, Arlington, VA, ³The George Washington University, Washington, ⁴University of California, San Diego, San Diego, CA, ⁵University of Colorado, Denver, CO, ⁶Clinica de la Costa, Barranquilla, Colombia, ⁷Allied Research Society, Barranquilla, Colombia, ⁸University of California, San Diego, San Diego, ⁹Universidad Libre de Barranquilla, Barranquilla, Colombia, ¹⁰The George Washington University, Alexandria
Background/Purpose: The MARCH study evaluates the efficacy of methotrexate monotherapy in patients with chikungunya-associated arthritis and aims to elucidate its pathologic mechanism via cytokine analysis.…
Abstract Number: 2152 • ACR Convergence 2025
Blau Syndrome: features beyond the classic triad and proposal for clinical criteria
Narendra Bagri¹, Nawazish Shaikh², Manisha jana³, Sushain kalsotra⁴, Krithika Rajkumar², Madhumita Roy Chowdhury², Neerja Gupta², Danveer Bhadu⁵, Vishal Gupta² and Rohan Chawla², ¹All India Institute of Medical Sciences(AIIMS), New Delhi, Delhi, India, ²All India Institute of Medical Sciences, Delhi, Delhi, India, ³ALL INDIA INSTITUTE OF MEDICAL SCIENCES, Delhi, ⁴All India Institute of Medical Sciences, Delhi, India, ⁵All India Institute of Medical Sciences, New Delhi, New Delhi, Delhi, India
Background/Purpose: This study describes the characteristic clinical and radiological findings and outcomes of patients with Blau syndrome from a single tertiary care hospital.Methods: A retrospective…
Abstract Number: 2039 • ACR Convergence 2025
To Hold or Not to Hold: Variability in Management of DMARDs in the Setting of Acute Infections – A Survey of Rheumatologists
Mollie Gellman¹, Medhasweta Sen², Ari Schwartz³, Peter Merkel⁴ and Nadine Mbuyi⁵, ¹Montefiore Medical Center, Bronx, NY, ²University of Virginia, Charlottesville, VA, ³Rheumatology Consultants PC, Brockton, MA, ⁴University of Pennsylvania, Philadelphia, PA, ⁵George Washington University, Washington, DC
Background/Purpose: Disease-modifying antirheumatic drugs (DMARDs) vary widely in their immunosuppressive activity. Guidance on managing DMARDs during acute infections is limited, particularly regarding when to hold…
Abstract Number: 1645 • ACR Convergence 2025
A sex-modified association between Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS) blood concentration and prevalent arthritis among young and middle-aged US adults
Queeneth Edwards¹, Samuel Mbadu¹, Jhy-Charm Soo² and Jian Zhang², ¹Georgia Southern University, Statesboro, GA, ²Georgia Southern University, statesboro
Background/Purpose: Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS) (PFAS), including Perfluorooctanoic acid (PFOA) and Perfluorooctane sulfonate (PFOS), are persistent environmental contaminants that may influence inflammatory joint diseases…
Abstract Number: 1362 • ACR Convergence 2025
Multimodal Spatial and Single-Cell Profiling of Synovial Tissue Reveals Macrophage Programs Associated with Biologic TherapyTreatment Response in Rheumatoid Arthritis
Mohammad Daud Khan¹, Matthew Dapas², Salina T Dominguez¹, Tyler Therron³, Kathleen Aren⁴, Mary Carns⁵, Hadijat Makinde⁵, Arthur M Mandelin¹, Eric M Ruderman¹, John F Seagrist⁵, Ruth Misha¹, Carla Marie Cuda⁵, Harris R Perlman⁵ and Deborah Rachelle Winter⁶, ¹Northwestern University, Chicago, ²Northwestern University Feinberg School of Medicine, Chicago, IL, ³Northwestern Feinberg School of Medicine, Chicago, IL, ⁴Northwestern University Division of Rheumatology, Chicago, IL, ⁵Northwestern University, Chicago, IL, ⁶Northwestern University, Skokie, IL
Background/Purpose: Rheumatoid arthritis (RA) is a chronic autoimmune disease driven by persistent synovial inflammation and progressive joint damage. Selecting an effective biologic therapy remains a…
Abstract Number: 0376 • ACR Convergence 2025
An Internet-Delivered, Arthritis-Tailored Cognitive Behavioral Therapy for Insomnia Program for People with Co-Morbid Sleep Disturbance: Comparing Baseline Characteristics of Cannabis Users and Non-Users
Nicole Andersen¹, Diane Lacaille², Josee Savard³, Elham Rahme¹, Paul Fortin⁴ and Deborah Da Costa⁵, ¹McGill University, Montreal, QC, Canada, ²Arthritis Research Canada, University of British Columbia, Vancouver, BC, Canada, ³Université Laval, Quebec, Canada, ⁴Centre ARThrite - CHU de Québec - Université Laval, Quebec, QC, Canada, ⁵McGill University, Pointe-Claire, QC, Canada
Background/Purpose: The use of cannabis among individuals with rheumatologic conditions has gained increasing attention due to potential effects on pain, mood, and overall quality of…
Abstract Number: 0199 • ACR Convergence 2025
Pain Phenotypes and Social Determinants of Health in Chronic Chikungunya Arthritis: A Cross-Sectional Study
Abebawork Adem¹, Alfonso Sucerquia², Jose Forero³, Juan Alzate², Larry Moreland⁴, Gary Firestein⁵, Andres Cadena⁶ and Aileen Chang⁷, ¹George Washington University, Washington, DC, DC, ²The George Washington University, Arlington, ³The George Washington University, Arlington, VA, ⁴University of Colorado, Denver, CO, ⁵University of California, San Diego, San Diego, CA, ⁶Clinica de la Costa, Barranquilla, Colombia, ⁷The George Washington University, Washington
Background/Purpose: Chronic chikungunya arthritis (CCA) is a long-term sequela of chikungunya virus infection marked by persistent pain, disability, and reduced quality of life. While nociplastic,…
Abstract Number: L02 • ACR Convergence 2024
Persistent Articular Infection and Host Reactive Responses Contribute to Brucella-Induced Spondyloarthritis in SKG Mice
Jerome Harms¹, Jens Eickhoff¹, Thomas Warner¹ and Judith Smith², ¹University of Wisconsin-Madison, Madison, WI, ²University of Wisconsin, Madison, WI
Background/Purpose: Brucellosis, one of the most prevalent zoonotic diseases worldwide, often results in osteoarticular complications including large joint and axial arthritis mimicking spondyloarthritis (SpA). Greater…
Abstract Number: 1325 • ACR Convergence 2024
The Association Between the Number of Teeth and All-Cause as Well as Cardiovascular Mortality Among Patients with RA: NHANES from 1999 to 2004
Jiaqian Zhang¹, Bo Chen², Geng Yin¹ and Qibing Xie³, ¹Department of Rheumatology and Immunology, chengdu, China (People's Republic), ²Chenbo, Chendu, Sichuan, China, ³Department of Rheumatology and Immunology, Chengdu, Sichuan, China
Background/Purpose: Cardiovascular Disease (CVD) is the main cause of death in patients with Rheumatoid Arthritis (RA), and a significant portion of CVD events occur in…
Abstract Number: 1851 • ACR Convergence 2024
Aberrant Tfh Cells Generated by Th17 Cell Plasticity in the Gut Promote Autoimmune Arthritis
Joyce Wu, The Ohio State University, Columbus, OH
Background/Purpose: Much remains unknown regarding T follicular helper 17 (Tfh17) cells in autoimmunity. We previously showed, and here ask why, egress of gut segmented filamentous…
Abstract Number: 2258 • ACR Convergence 2024
The Window of Opportunity: A Concept Also Applicable to Undifferentiated Arthritis
Patricia Quiroga Colina¹, María Paula Álvarez², Maryia Nikitsina³, Marina Dueñas⁴, Juan Carlos Sáez⁵, Cristina Valero⁶, Jesus A García-Vadillo⁷, María Ahijón Lana³, Santos Castañeda⁸, Eva Tomero Muriel⁹, Esther Vicente-rabaneda⁸, Ana Romero⁵, Irene Llorente⁵, Miren Uriarte-Ecenarro⁵, Rosario García-Vicuña², Ana Ortiz⁸ and Isidoro González-Álvaro³, ¹Division of Rheumatology, Hospital Universitario de La Princesa, Madrid, Spain, ²Hospital Universitario de La Princesa, Madrid, Madrid, Spain, ³University Hospital La Princesa, Madrid, Madrid, Spain, ⁴Servicio de Reumatología Hospital La Princesa, Madrid, Madrid, Spain, ⁵H.U.La Princesa, Madrid, Spain, ⁶Hospital de la Princesa, Madrid, Spain, ⁷H La Princesa, Madrid, Spain, ⁸Hospital Universitario de la Princesa, Madrid, Spain, ⁹La Princesa Hospital, Madrid, Madrid, Spain
Background/Purpose: The window of opportunity is well established in patients with rheumatoid arthritis (RA) but it is unclear in patients with undifferentiated arthritis (UA). This study…
Abstract Number: 0258 • ACR Convergence 2024
Nationwide Analysis of Adult Non-Gonococcal Bacterial Septic Arthritis Hospitalizations from the National Inpatient Sample 2016 to 2020
Saman Tanveer¹, Augustine Manadan² and Diego Cornejo-Gonzalez³, ¹John H. Stroger Jr. Hospital of Cook County, Chicago, IL, ²Rush University Medical Center, Chicago, IL, ³John H. Stroger Jr. Hospital of Cook county, Chicago
Background/Purpose: Septic arthritis is a rheumatologic emergency associated with significant morbidity and mortality. This study examines the descriptive characteristics and risk factors associated with in-hospital…
Abstract Number: 0259 • ACR Convergence 2024
Whipple’s Disease in Patients Initially Diagnosed with Rheumatic Diseases: A Case Series
Judith den Hertog¹, Maike Wientjes¹, Jaap ten Oever², Merel Opdam¹, Denise Telgt¹ and Alfons den Broeder¹, ¹Sint Maartenskliniek, Ubbergen, Netherlands, ²Radboudumc, Nijmegen, Netherlands
Background/Purpose: Whipple’s disease is a presumably rare, chronic infectious disease caused by the bacterium Tropheryma whipplei. Symptoms include weight loss, diarrhea, abdominal discomfort, joint pain…
Abstract Number: 0262 • ACR Convergence 2024
Bartonella Endocarditis as an Important Mimic of ANCA Associated Vasculitis: Results of a Large Single Center Descriptive Analysis
Adam Brown¹, Adil Vural², Cassandra Calabrese³ and Leonard Calabrese², ¹Cleveland Clinic Foundation, Cleveland, OH, ²Cleveland Clinic, Cleveland, OH, ³Cleveland Clinic Foundation, Cleveland Heights, OH
Background/Purpose: Infective Endocarditis (IE) is an important mimic of numerous forms of systemic vasculitis and especially Anti-Neutrophilic Cytoplasmic Antibody vasculitis (AAV). Bartonella endocarditis (BE) is…
Abstract Number: 0059 • ACR Convergence 2023
GM-CSF by Natural Killer Cells Drives Inflammatory Arthritis in HIV-Infected Humanized Mice
Can Sungur¹, Li-ping Yang², Liang Shan¹ and wayne Yokoyama³, ¹Washington University, St. Louis, MO, ²Washington University in St. Louis, St. Louis, MO, ³Washington University School of Medicine, St. Louis, MO
Background/Purpose: Human immunodeficiency virus (HIV) remains a significant life-threatening agent and burden on public health. Lesser studied and understood aspects of HIV include HIV-associated inflammatory…

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