Abstracts tagged "Arthritis, Infectious"

Abstract Number: L02 • ACR Convergence 2024
Persistent Articular Infection and Host Reactive Responses Contribute to Brucella-Induced Spondyloarthritis in SKG Mice
Jerome Harms¹, Jens Eickhoff¹, Thomas Warner¹ and Judith Smith², ¹University of Wisconsin-Madison, Madison, WI, ²University of Wisconsin, Madison, WI
Background/Purpose: Brucellosis, one of the most prevalent zoonotic diseases worldwide, often results in osteoarticular complications including large joint and axial arthritis mimicking spondyloarthritis (SpA). Greater…
Abstract Number: 0258 • ACR Convergence 2024
Nationwide Analysis of Adult Non-Gonococcal Bacterial Septic Arthritis Hospitalizations from the National Inpatient Sample 2016 to 2020
Saman Tanveer¹, Augustine Manadan² and Diego Cornejo-Gonzalez³, ¹John H. Stroger Jr. Hospital of Cook County, Chicago, IL, ²Rush University Medical Center, Chicago, IL, ³John H. Stroger Jr. Hospital of Cook county, Chicago
Background/Purpose: Septic arthritis is a rheumatologic emergency associated with significant morbidity and mortality. This study examines the descriptive characteristics and risk factors associated with in-hospital…
Abstract Number: 0259 • ACR Convergence 2024
Whipple’s Disease in Patients Initially Diagnosed with Rheumatic Diseases: A Case Series
Judith den Hertog¹, Maike Wientjes¹, Jaap ten Oever², Merel Opdam¹, Denise Telgt¹ and Alfons den Broeder¹, ¹Sint Maartenskliniek, Ubbergen, Netherlands, ²Radboudumc, Nijmegen, Netherlands
Background/Purpose: Whipple’s disease is a presumably rare, chronic infectious disease caused by the bacterium Tropheryma whipplei. Symptoms include weight loss, diarrhea, abdominal discomfort, joint pain…
Abstract Number: 0262 • ACR Convergence 2024
Bartonella Endocarditis as an Important Mimic of ANCA Associated Vasculitis: Results of a Large Single Center Descriptive Analysis
Adam Brown¹, Adil Vural², Cassandra Calabrese³ and Leonard Calabrese², ¹Cleveland Clinic Foundation, Cleveland, OH, ²Cleveland Clinic, Cleveland, OH, ³Cleveland Clinic Foundation, Cleveland Heights, OH
Background/Purpose: Infective Endocarditis (IE) is an important mimic of numerous forms of systemic vasculitis and especially Anti-Neutrophilic Cytoplasmic Antibody vasculitis (AAV). Bartonella endocarditis (BE) is…
Abstract Number: 1325 • ACR Convergence 2024
The Association Between the Number of Teeth and All-Cause as Well as Cardiovascular Mortality Among Patients with RA: NHANES from 1999 to 2004
Jiaqian Zhang¹, Bo Chen², Geng Yin¹ and Qibing Xie³, ¹Department of Rheumatology and Immunology, chengdu, China (People's Republic), ²Chenbo, Chendu, Sichuan, China, ³Department of Rheumatology and Immunology, Chengdu, Sichuan, China
Background/Purpose: Cardiovascular Disease (CVD) is the main cause of death in patients with Rheumatoid Arthritis (RA), and a significant portion of CVD events occur in…
Abstract Number: 1851 • ACR Convergence 2024
Aberrant Tfh Cells Generated by Th17 Cell Plasticity in the Gut Promote Autoimmune Arthritis
Joyce Wu, The Ohio State University, Columbus, OH
Background/Purpose: Much remains unknown regarding T follicular helper 17 (Tfh17) cells in autoimmunity. We previously showed, and here ask why, egress of gut segmented filamentous…
Abstract Number: 2258 • ACR Convergence 2024
The Window of Opportunity: A Concept Also Applicable to Undifferentiated Arthritis
Patricia Quiroga Colina¹, María Paula Álvarez², Maryia Nikitsina³, Marina Dueñas⁴, Juan Carlos Sáez⁵, Cristina Valero⁶, Jesus A García-Vadillo⁷, María Ahijón Lana³, Santos Castañeda⁸, Eva Tomero Muriel⁹, Esther Vicente-rabaneda⁸, Ana Romero⁵, Irene Llorente⁵, Miren Uriarte-Ecenarro⁵, Rosario García-Vicuña², Ana Ortiz⁸ and Isidoro González-Álvaro³, ¹Division of Rheumatology, Hospital Universitario de La Princesa, Madrid, Spain, ²Hospital Universitario de La Princesa, Madrid, Madrid, Spain, ³University Hospital La Princesa, Madrid, Madrid, Spain, ⁴Servicio de Reumatología Hospital La Princesa, Madrid, Madrid, Spain, ⁵H.U.La Princesa, Madrid, Spain, ⁶Hospital de la Princesa, Madrid, Spain, ⁷H La Princesa, Madrid, Spain, ⁸Hospital Universitario de la Princesa, Madrid, Spain, ⁹La Princesa Hospital, Madrid, Madrid, Spain
Background/Purpose: The window of opportunity is well established in patients with rheumatoid arthritis (RA) but it is unclear in patients with undifferentiated arthritis (UA). This study…
Abstract Number: 0970 • ACR Convergence 2023
Comparison of Survival on Treatment and Severe Infection Among New Users of Biosimilar vs. Originator Biologics in Inflammatory Arthritis: Population-based Evidence from a Natural Experiment Due to a Policy Change
Diane Lacaille¹, J. Antonio Avina-Zubieta², Yufei Zheng², Na Lu² and Hui Xie³, ¹Arthritis Research Canada, University of British Columbia, Vancouver, BC, Canada, ²Arthritis Research Canada, Vancouver, BC, Canada, ³Simon Fraser University, Richmond, BC, Canada
Background/Purpose: British Columbia's health policy mandated that all new anti-TNF initiations after June 2017 use biosimilars when available, providing the context for a natural experiment.…
Abstract Number: 1100 • ACR Convergence 2023
A Comparison of Characteristics of Patients with Crystalline and Septic Arthritis Confirmed by Synovial Fluid Analysis: Towards the Development of a Diagnostic Rule
Maria Salgado Guerrero¹, Mariana Urquiaga¹, Nishah Panchani² and Angelo Gaffo³, ¹University of Alabama at Birmingham, Birmingham, AL, ²Tinsley Harrison Internal Medicine Residency Program, University of Alabama at Birmingham, Arlington, TX, ³Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, AL; Birmingham VA Medical Center, Birmingham, AL
Background/Purpose: Distinguishing crystalline from septic arthritis is a common challenge in patients admitted with acute joint inflammation. Arthrocentesis for synovial fluid analysis is considered the…
Abstract Number: 1139 • ACR Convergence 2023
From Skin to Bone Lesions: A Pioneer Study Unraveling the Underdiagnosis of SAPHO Syndrome in the Dominican Republic
Leeany Maletta¹, Diana Jimenez² and Rosanna de Jesus³, ¹UNIBE School of Medicine, San Antonio, TX, ²UNIBE School of Medicine, Miami, FL, ³Hospital General Plaza de la Salud, Distrito Nacional, Dominican Republic
Background/Purpose: SAPHO syndrome is a rare chronic inflammatory condition that affects the skin and osteoarticular structures. Despite being first described over 30 years ago, it…
Abstract Number: 1670 • ACR Convergence 2023
Exacerbation of Immune-mediated Inflammatory Diseases in COVID19 Sequelae
CAMILA CAETANO¹, Tamiris Azamor¹, Nikki M. Meyer¹, Cassandra Calabrese², Leonard Calabrese², Nicolas Piuzzi³, M. Elaine Husni², Suan-Sin Foo¹ and Weiqiang Chen¹, ¹Cleveland Clinic / Infection Biology Program, Global Center for Pathogen Research and Human Health, Lerner Research Institute, Cleveland, OH, ²Cleveland Clinic / Department of Rheumatic and Immunologic Diseases, Cleveland, OH, ³Cleveland Clinic / Department of Orthopedic Surgery, Cleveland, OH
Background/Purpose: Patients with underlying immune-mediated inflammatory diseases (IMIDs), such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), have a higher susceptibility to severe COVID19…
Abstract Number: 1826 • ACR Convergence 2023
Investigating the Health Profiles and the Prevalence and Correlates of Cannabis Use Among Patients Accessing Rheumatologic Care in Alberta, Canada
Elaine Yacyshyn, Simran Gulati, Samuel Lowe, Allyson Jones, Tarek Turk, Shelby Yamamoto, Kali Gregg, Linda Kolewaski, Joanne Olson, Pauline Paul and Cheryl Sadowski, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Implications of using cannabis as therapeutics in a growing number of diseases coupled with increasing public awareness are leading to an increase in patient…
Abstract Number: 0059 • ACR Convergence 2023
GM-CSF by Natural Killer Cells Drives Inflammatory Arthritis in HIV-Infected Humanized Mice
Can Sungur¹, Li-ping Yang², Liang Shan¹ and wayne Yokoyama³, ¹Washington University, St. Louis, MO, ²Washington University in St. Louis, St. Louis, MO, ³Washington University School of Medicine, St. Louis, MO
Background/Purpose: Human immunodeficiency virus (HIV) remains a significant life-threatening agent and burden on public health. Lesser studied and understood aspects of HIV include HIV-associated inflammatory…
Abstract Number: 0196 • ACR Convergence 2023
Limited Regulatory T Cell Response in Post-Chikungunya Viral Arthritis: A Therapeutic Opportunity?
Aileen Chang¹, Sarah Tritsch¹, Carlos Herrera¹, Liliana Encinales², Andres Cadena³, Wendy Rosales⁴, Evelyn Mendoza⁵, Samuel Simmens¹, Richard Amdur⁶, Paige Fierbaugh¹, Abigale Proctor¹, Alfonso Sucerquia¹, Christopher Mores¹, David Boyle⁷, Gary Firestein⁷ and Gary Simon¹, ¹George Washington University, Washington, DC, ²Allied Research Society, Barranquilla, Colombia, ³Clinica de la Costa, Barranquilla, Colombia, ⁴Universidad Libre, Barranquilla, Colombia, ⁵Universidad Libre, Bogotá, Colombia, ⁶Northwell, Washington, DC, ⁷University of California San Diego, San Diego, CA
Background/Purpose: The objective was to define the relationship between chronic chikungunya (CHIKV) post-viral arthritis disease severity, interleukin (IL)-2, and T cell subsets in order to…
Abstract Number: 0197 • ACR Convergence 2023
Development of a Chikungunya Arthritis Disease Activity Score
Aileen Chang¹, Samuel Simmens¹, Hugh Watson², Richard Amdur³, Andre Siqueira⁴, Abigale Proctor¹, Sarah Tritsch¹, Carlos Herrera¹, Liliana Encinales⁵, Alfonso Sucerquia¹, Alejandro Jaller¹, Juan Jose Jaller⁶, Kennedy Amaral⁷, Gary Simon¹, Larry Moreland⁸, Andres Cadena⁹ and Gary Firestein¹⁰, ¹George Washington University, Washington, DC, ²Evotec, Lyon, France, ³Northwell, Washington, DC, ⁴Fiocruz, Rio, Brazil, ⁵Allied Research Society, Barranquilla, Colombia, ⁶Reumatologos SAS, Barranquilla, Colombia, ⁷Institute of Diagnostic Medicine of Cariri, Pernambuco, Brazil, ⁸University of Colorado, Denver, CO, ⁹Clinica de la Costa, Barranquilla, Colombia, ¹⁰University of California San Diego, San Diego, CA
Background/Purpose: Chikungunya virus is an alphavirus spread by mosquitos that causes a debilitating chronic arthritis that has no standard treatment to date. The objective of…

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