Abstracts tagged "Arthritis and mouse model"

Abstract Number: 2571 • 2015 ACR/ARHP Annual Meeting
Anti-IL-6 Receptor Antibody Prevents Loss of Bone Strength in a Mouse Model of Collagen-Induced Arthritis
Hiroto Yoshida, Yuanyuan Bi, Miho Suzuki, Keisuke Tanaka and Yoshihiro Matsumoto, Product Research Department, Chugai Pharmaceutical Co., Ltd., Gotemba, Japan
Background/Purpose: Rheumatoid arthritis (RA) is a disease that typically induces secondary osteoporosis, which increases the risk of bone fractures and, consequently, mortality. Bone fracture is…
Abstract Number: 268 • 2014 ACR/ARHP Annual Meeting
The Effect of Treatment with Resiniferatoxin and Capsaicin on Dynamic Weight Bearing Measures and Evoked Pain Responses in a Chronic Inflammatory Arthritis Murine Model
Joseph Bert¹, Christopher W. Dorman², Sandra Frizelle², Sonia C. Funkenbusch², Hollis E. Krug³ and Maren L. Mahowald⁴, ¹Internal Medicine, University of Minnesota Internal Medicine Residency, Minneapolis, MN, ²Research, Minneapolis VA Health Care System, Minneapolis, MN, ³Medicine, VA Health Care System, Minneapolis, MN, ⁴Medicine, University of Minnesota Medical School and Minneapolis VA Health Care System, Minneapolis, MN
Background/Purpose: Capsaicin (CAP) and Resiniferatoxin (RTX) are vanilloid receptor agonists that when given by intra-articular injections, can normalize Evoked Pain Scores (EPS) and Automated Dynamic…

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