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Abstracts tagged "arthritis and kinase"

  • Abstract Number: 1097 • ACR/ARHP Annual Meeting 2015

    Pre-Clinical Development of a Novel, Potent and Selective BTK Inhibitor for Autoimmune Disease and Inflammation Including Arthritis

    Stephen Morris, Alain Laurent, Lori Jerome, Alain Boudreault, Helen Ashdown, Yannick Rose, Patrick Bureau, Shou-Yun Yin, Patrick Cleroux, Delphine Labit, Nicholas Henry, Marie-Noelle Tremblay, Marlyna Guerard, Emilie Dumas Bérubé and Kosta Spathis, Pharmascience Inc., Ville St-Laurent, QC, Canada

    Background/Purpose: Bruton’s tyrosine kinase (BTK) is an important component of B cell and Fc receptor signaling and has been shown to be critical for B-cell…
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