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Abstracts tagged "arthritis and cytokines"

  • Abstract Number: 1734 • ACR/ARHP Annual Meeting 2014

    IL-22 Plays a Significant Role in the Initiation and Augmentation of Th17-Dependent Experimental Arthritis

    Debbie M. Roeleveld1, Renoud Marijnissen2, Rebecca Rogier3, Birgitte Walgreen1, Monique M. Helsen3, Liduine van den Bersselaar3, Shahla Abdollahi-Roodsaz4, Wim B. van den Berg3 and Marije I. Koenders3, 1Experimentel Rheumatology, Radboud university medical center, Nijmegen, Netherlands, 2Experimental Rheumatology, Radboud University Medical Center, Nijmegen, Netherlands, 3Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands, 4Rheumatology, Radboud university medical center, Nijmegen, Netherlands

    Background/Purpose Rheumatoid arthritis (RA) is a chronic, inflammatory autoimmune disease that leads to progressive destruction of cartilage and bone. IL-22 and IL-22-producing T helper cells…

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