Abstracts tagged "APL and antibodies"

Abstract Number: 1 • 2013 ACR/ARHP Annual Meeting
Anti-â2GP1- Domain-1 Antibodies Are a Marker Of APS Severity
Nancy Agmon-Levin¹, Luciana Seguro², Cristina Rosário³, Michael Mahler⁴, Mariele Gatto⁵, Nir Tomer⁶, Elaine P. Leon⁷, Andrea Doria⁸, László Kovács⁹, Nathalie Costedoat-Chalumeau¹⁰, Boris Gilburd¹¹ and Yehuda Shoenfeld¹², ¹The Zabludowicz Center for Autoimmune Diseases, Tel-Hashomer, Israel, ²Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ³Internal Medicine Department, Hospital de Pedro Hispano, Rua Dr. Eduardo Torres Matosinhos, Porto, Portugal, ⁴Research, INOVA Diagnostics, San Diego, CA, ⁵Department of Medicine-DIMED, University of Padova, Padova, Italy, ⁶The Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel, ⁷Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁸Division of Rheumatology, University of Padova, Padova, Italy, ⁹Department of Rheumatology, University of Szeged, Szeged, Hungary, ¹⁰Internal Medicine, Hopital Cochin, Paris, France, ¹¹The Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel, ¹²The Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Ramat Gan, Israel
Background/Purpose: Autoantibodies targeting Domain-1(D1) of beta-2-glycoprotein-1(β2GP1) are common among patients with the antiphospholipid syndrome (APS)1. However, few studies assessed their clinical relevance and correlation with…