ACR Meeting Abstracts

ACR Meeting Abstracts

  • Meetings
    • ACR Convergence 2024
    • ACR Convergence 2023
    • 2023 ACR/ARP PRSYM
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • ACR Meetings

Abstracts tagged "antiphospholipid syndrome"

  • Abstract Number: 0837 • ACR Convergence 2024

    Bispecific Autoantigen-T Cell Engagers (BaiTE) to Selectively Target Autoreactive B Cells in Antiphospholipid Syndrome

    Yuanxuan Xia1, Jin Liu1, Alexander Pearlman1, Brian Mog1, Elana Shaw1, Kyle J. Kaeo1, Colin Gliech1, Brock Moritz1, Tolulope Awosika1, Sarah DiNapoli1, Stephanie Glavaris1, Jiaxin Ge1, Tushar Nichakawade1, Nikita Marcou1, Suman Paul1, Drew Pardoll1, Chetan Bettegowda1, Daniel Goldman2, Michelle Petri2, Antony Rosen1, Kenneth W. Kinzler1, Shibin Zhou1, Bert Vogelstein1 and Maximilian F. Konig1, 1The Johns Hopkins University School of Medicine, Baltimore, MD, 2Johns Hopkins University School of Medicine, Timonium, MD

    Background/Purpose: Available drugs to treat autoimmune diseases are indiscriminate, suppressing self-reactive and protective immune responses alike. This lack of therapeutic precision results in infection and…
  • Abstract Number: 0101 • ACR Convergence 2024

    Metabolomic Profiling Reveals a Role for Citric Acid Cycle Dysfunction in Antiphospholipid Syndrome Neutrophils

    Ajay Tambralli1, Megan Radyk1, Kaitlyn Sabb1, Li Zhang1, Harrison Wong1, Emily Becker1, Srilakshmi Yalavarthi1, Claire Hoy1, Cyrus Sarosh2, Jacqueline Madison1, Yu Zuo1, Jason Knight1 and Costas Lyssiotis1, 1University of Michigan, Ann Arbor, MI, 2University of Michigan, Temperance, MI

    Background/Purpose: As early effectors of the immune response, neutrophils must access energy rapidly. Neutrophils rely on glycolysis for antimicrobial functions such as phagocytosis and reactive…
  • Abstract Number: 0117 • ACR Convergence 2024

    Validation of the 2023 American College of Rheumatology/European League Against Rheumatism Antiphospholipid Syndrome Classification Criteria in the Pediatric Population

    Daniel Bar1, Stanley Niznik2, Shiri Spielman3, Rotem Semo-Oz4, Assaf Barg3, Sarina Levy-Mendelovich3, Gili Kenet2, Nancy Agmon- Levin2 and Irit Tirosh5, 1Edmond and Lilly Safra Children's Hospital, Sheba Medical Center, Herzliya, HaMerkaz, Israel, 2Sheba Medical Center, Tel Aviv, Israel, 3Edmond and Lilly Safra Children's Hospital, Sheba Medical Center, Tel Aviv, Israel, 4Edmond and Lilly Safra Children's Hospital, Sheba Medical Center, Herzliya, Israel, 5Edmond and Lilly Safra Children's Hospital, Sheba Medical Center, Savyon, Israel

    Background/Purpose: Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by arterial, venous or microvascular thrombosis, obstetric morbidity and/or non-thrombotic manifestations. The 2023 ACR/EULAR APS…
  • Abstract Number: 0838 • ACR Convergence 2024

    The Mechanistic Impact of IgA anti-beta-2 Glycoprotein I on Accelerated Atherosclerosis in Primary APS

    Kavya Sugur1, Emily Chong1, Srilakshmi Yalavarthi2, Katarina Kmetova3, Lyndsay Kluge1, Wenying Liang2, Cyrus Sarosh4, NaveenKumar Somanathapura K2, Jacqueline Madison2, Ajay Tambralli2, Jason Knight2 and Yu Zuo2, 1Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Ann Arbor, MI, 2University of Michigan, Ann Arbor, MI, 3Division of Rheumatology, University of Michigan, Ann Arbor, Michigan, USA, Ann Arbor, MI, 4University of Michigan, Temperance, MI

    Background/Purpose: Antiphospholipid syndrome (APS) is an acquired thrombo-inflammatory disease characterized by persistent antiphospholipid antibodies (aPL). APS patients experience significant morbidity and mortality, much of which…
  • Abstract Number: 0102 • ACR Convergence 2024

    Single-cell Profiling of Dermal Endothelial Cells Identifies Unique Molecular Pathways Associated with Small-Vessel Events and Nephropathy in Antiphospholipid Syndrome

    Wenying Liang1, Qinmengge Li1, Jacqueline Madison1, Rachael Wasikowski2, Srilakshmi Yalavarthi1, Cyrus Sarosh3, Yu Zuo1, Pei-Suen Tsou1, Lam Tsoi1 and Jason Knight1, 1University of Michigan, Ann Arbor, MI, 2Michigan, Dept. of Dermatology, Ann Arbor, MI, 3University of Michigan, Temperance, MI

    Background/Purpose: Beyond thrombotic events, antiphospholipid syndrome (APS) is also associated with an organ-threatening small-vessel vasculopathy that lacks specific treatments. A soon-to-be-published skin biopsy study focusing…
  • Abstract Number: 0118 • ACR Convergence 2024

    Performance of the 2023 ACR/EULAR Classification Criteria for Antiphospholipid Syndrome in a Mexican Cohort

    Erik Cimé-Aké1, Gabriela Hernández-Molina2, Amaya Llorente-Chávez3 and Eduardo Martin Nares2, 1Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Immunology and Rheumatology Department, Mexico City, Mexico, 2Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 3Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Hematology Department, Mexico City, Distrito Federal, Mexico

    Background/Purpose: The 2023 ACR/EULAR classification criteria (2023 AECC) for antiphospholipid syndrome (APS) were recently published. The new criteria require an entry criterion and employe a…
  • Abstract Number: 0839 • ACR Convergence 2024

    Comprehensive Single-cell Analysis Reveals Interferon Pathway Activation and Aberrant B Cell Dynamics in APS Autoimmunity

    Haoyu Pan, Xiaohan Wei, Jinyi Qian, Shuyi Yu, Zhixia Yang, Zetao Ding, Chengde Yang and Hui Shi, Department of Rheumatology and lmmunology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, Shanghai, China (People's Republic)

    Background/Purpose: Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized with the presence of pathogenic antiphospholipid antibodies (aPL) by autoreactive B cells. However, it remains…
  • Abstract Number: 0103 • ACR Convergence 2024

    CD10highLow-Density Granulocytes Is a Potential Marker of Disease Activity in Antiphospholipid Syndrome

    chun Li, Peking University People's Hospital, Beijing, China

    Background/Purpose: To investigate the relationship between CD10highLow-Density Granulocytes (LDG) and disease activity in antiphospholipid syndrome(APS).Methods: This study included 99 patients with APS who were treated…
  • Abstract Number: 0119 • ACR Convergence 2024

    Clinical and Serological Distinctions and Evolutionary Predictors in Antiphospholipid Syndrome and Systemic Lupus Erythematosus: A Multicenter Cohort Analysis

    Basant Elnady1, Ziyad Alakkas2, Sultana Abdulaziz3, Hussain Halabi4, Ahmed A. G. Ibrahim5, Hoda E. Draz5, Mohammed Attar6, Hassan Daghasi7, Abeer Alhalwani8, Reman Shaker9 and Ghadeer Maher Elsheikh10, 1Al Hada Forces Hospital, Rheumatology Department, Taif, Saudi Arabia, 2King Faisal Medical Complex, Taif, Saudi Arabia, 3King Fahad Hospital, Jeddah, Saudi Arabia, 4King Faisal Specialist Hospital & Research Center, Jeddah, Saudi Arabia, 5Benha University, Benha, Egypt, 6al hada armed forces hospital, Taif, Saudi Arabia, 7Alhada military hospital, Taif, Saudi Arabia, 8East Jeddah hospital, Jeddah, Saudi Arabia, 9King Faisal Specialist Hospital and Research centre, Jeddah, Saudi Arabia, 10Menoufia University, Menoufia, Egypt

    Background/Purpose: Antiphospholipid syndrome (APS) is closely linked with Systemic Lupus erythematosus (SLE) and can influence patient outcomes. The interplay between APS and SLE, including the evolution…
  • Abstract Number: 0840 • ACR Convergence 2024

    The Platelet Adenosinergic Axis as a Novel Therapeutic Target for Thrombotic APS

    NaveenKumar Somanathapura K1, Thalia Newman2, Srilakshmi Yalavarthi1, Bruna Mazetto Fonseca1, Kaitlyn Sabb1, Katarina Kmetova3, Emily Chong1, Caroline Ranger1, Cyrus Sarosh4, Jacqueline Madison1, Ajay Tambralli1, Jordan Schaefer1, Michael Holinstat1, Yu Zuo1 and Jason Knight1, 1University of Michigan, Ann arbor, MI, 2University of Michigan, Ann Arbor, MI, 3Division of Rheumatology, University of Michigan, Ann Arbor, Michigan, USA, Ann Arbor, MI, 4University of Michigan, Temperance, MI

    Background/Purpose: How to most effectively inhibit antiphospholipid antibodies (aPL)-mediated platelet activation remains incompletely understood. CD73 is an ectoenzyme expressed on the platelet surface that generates…
  • Abstract Number: 0104 • ACR Convergence 2024

    Proteomic Analysis Identifies Neutrophil Defensin 1 as a Biological Marker for Antiphospholipid Syndrome

    Yuebing Wang1 and chun Li2, 1Department of Rheumatology and Immunology, Peking University People’s Hospital & Beijing Key Laboratory for Rheumatism Mechanism and Immune Diagnosis, Beijing, China, Beijing, China, 2Peking University People's Hospital, Beijing, China

    Background/Purpose: Antiphospholipid syndrome (APS) is a distinct type of thrombophilia caused by autoantibodies, characterized by repeated thrombosis and complications during pregnancy. This study aimed to…
  • Abstract Number: 0120 • ACR Convergence 2024

    Vascular Liver Disorders in Patients with Antiphospholipid Syndrome: A Retrospective National Multicentre Study

    Mathilde Katims1, Marc Pineton de Chambrun2, Cecine Yelnik3, Arthur Mageau4, Ada Clarke1, Matthias Papo5, Zahir Amoura6, Marc Lambert3, Thomas Papo4, Laure Delaval7, Pierre-Emmanuel Rautou8, Nathalie Costedoat-chalumeau9 and Karim Sacré4, 1Assistance Publique Hopitaux de Paris, Paris, France, 2Sorbonne Université, Paris, France, 3Université de Lille, Lille, France, 4Université Paris Cité, Paris, France, 5Department of Internal Medicine, Cochin Hospital, National Referral Center for Rare Systemic Autoimmune and Autoinflammatory Diseases of Ile de France, East and West, Paris Cité University, Assistance Publique – Hôpitaux de Paris, Paris, France, 6French National Reference Centre for Systemic Lupus Erythematosus, Pitié-Salpêtrière Hospital, Paris, France, 7Hopital Delafontaine, Saint Denis, France, 8Université Paris Cité, Clichy, France, 9University Paris Cité, Paris, France

    Background/Purpose: Antiphospholipid syndrome (APS) is a thrombo-inflammatory disease propelled by autoantibodies that recognize cell surface phospholipids and phospholipid binding proteins. The result is an increased…
  • Abstract Number: 0841 • ACR Convergence 2024

    Clinical and Biologic Predictors of Thrombosis in Persistently Antiphospholipid Antibody Positive Patients: Prospective Analysis of the International APS ACTION Clinical Database and Repository (“Registry”)

    Jonathan Thaler1, Michael Parides1, Danieli Andrade2, Diana Paredes-Ruiz3, Maria Tektonidou4, Vittorio Pengo5, Savino Sciascia6, Cecilia Nalli7, Guilherme Ramires de Jesús8, Paul Fortin9, Maria Efthymiou10, H Michael Belmont11, Michelle Petri12, Ricard Cervera13, Leslie Skeith14, TATSUYA ATSUMI15, Chary Lopez-Pedrera16, Yu Zuo17, David Branch18, Rohan Willis19, Nina Kello20, Zhuoli Zhang21, Esther Rodriguez-Almaraz22, Bahar Artim Esen23, Jose Pardos-Gea24, Guillermo Pons-Estel25, Giulia Pazzola26, Hui Shi17, Ali Duarte-Garcia27, Medha Barbhaiya1, Cécile Yelnik28, Pierluigi Meroni29, Robert Roubey30, Maria Laura Bertolaccini31, Hannah Cohen32, Jacob Rand33 and Doruk Erkan1, and on behalf of APS ACTION, 1Hospital for Special Surgery, New York, NY, 2University of São Paulo, São Paulo, SP, Brazil, 3Autoimmune Diseases Research Unit. Biocruces Bizkaia Health Research Institute, Baracaldo, Spain, 4National and Kapodistrian University of Athens, Athens, Greece, 5Thrombosis Research Laboratory, Department of Cardio-Thoracic-Vascular Sciences and Public Health, University of Padova, Padova, Italy, 6University of Turin, Torino, Turin, Italy, 7ASST SPEDALI CIVILI DI BRESCIA, Brescia, Italy, 8Universidade do Estado do Rio de Janeiro, Rio De Janeiro, Brazil, 9Centre ARThrite - CHU de Québec - Université Laval, Quebec, QC, Canada, 10University College London, London, United Kingdom, 11NYU School of Medicine, New York, NY, 12Johns Hopkins University School of Medicine, Timonium, MD, 13Hospital Clinic de Barcelona, Barcelona, Spain, 14University of Calgary, Calgary, ON, Canada, 15Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 16IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Andalucia, Spain, 17University of Michigan, Ann Arbor, MI, 18University of Utah and Intermountain Healthcare, Salt Lake City, UT, 19University of Texas Medical Branch, Galveston, TX, 20Northwell Health, Brooklyn, NY, 21Peking University First Hospital, Beijing, China, 22Hospital Universitario 12 de Octubre, Madrid, Spain, 23Istanbul University, Istanbul Faculty of Medicine, Division of Rheumatology, Istanbul, Turkey, 24Vall d'Hebron University Hospital, Barcelona, Spain, 25CREAR, Rosario, Argentina, 26Rheumatology Unit, Azienda USL IRCCS di Reggio Emilia, Reggio Emilia, Italy, 27Mayo Clinic, Rochester, MN, 28lille university, Lille, France, 29IRCCS Istituto Auxologico Italiano 100%, Cusano Milanino, Milan, Milan, Italy, 30Division of Rheumatology, Allergy, and Immunology, University of North Carolina, Chapel Hill, NC, 31King's College London, London, United Kingdom, 32University College London Hospitals NHS Foundation Trust, London, United Kingdom, 33Weill Cornell Medical Center, Bronx, NY

    Background/Purpose: There is a lack of high-quality data to inform risk-stratified long-term thrombosis prevention strategies in patients with persistently positive antiphospholipid antibodies (aPL). The APS…
  • Abstract Number: 0105 • ACR Convergence 2024

    Novel Autoantibodies Identified in the Antiphospholipid Syndrome

    Shikai Hu1, Yangzhong Zhou1, Menghua Cai1, Mengtao Li2 and JIULIANG ZHAO1, 1Peking Union Medical College Hospital, Beijing, China, 2Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China 2National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Ministry of Science & Technology, Beijing, China

    Background/Purpose: The antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by arterial, venous, or microvascular thrombosis, recurrent pregnancy morbidity, or non-thrombotic manifestations in the…
  • Abstract Number: 0121 • ACR Convergence 2024

    Intra-renal Involvement in Primary Antiphospholipid Antibodies Syndrome: Data from Two Italian Centers

    Liala Moschetti1, Savino Sciascia2, Micaela Fredi3, Mattia Zappa4, Massimo Radin5, Ilaria Cavazzana3, Stefania Affatato6, Cecilia Nalli7, Laura Andreoli8, Federico Alberici9, Franco Franceschini1, Dario Roccatello10 and Angela Tincani11, 1Scleroderma Unit, Rheumatology and Clinical Immunology Unit, ERN ReCONNET, ASST Spedali Civili, Brescia, Italy, Brescia, Italy, 2University of Turin, Torino, Turin, Italy, 3Rheumatology and Clinical Immunology Unit and Department of Clinical and Experimental Sciences, ERN ReCONNET; ASST Spedali Civili and University of Brescia, Italy, Brescia, Italy, 4Nephrology Unit and Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health; ASST Spedali Civili and University of Brescia, Italy, Brescia, Italy, 5University of Turin, Turin, Italy, 6Nephrology Unit, University of Brescia, ASST Spedali Civili, Brescia, Italy, Brescia, Italy, 7ASST SPEDALI CIVILI DI BRESCIA, Brescia, Italy, 8University of Brescia, Brescia, Italy, 9Nephrology Unit, ASST Spedali Civili di Brescia, Brescia, Italy, 10Nephrology and Dialysis Unit and Center of Immuno-Rheumatology and Rare Diseases (CMID) and Department of Clinical and Biological Sciences; San Giovanni Bosco Hospital and University of Turin, Italy, Turin, Italy, 11ASST Spedali Civili-University of Brescia, Brescia, Italy

    Background/Purpose: Antiphospholipid antibodies nephropathy (aPL-N) is defined by thrombotic microangiopathy (TMA) early lesions and late lesions such fibro-intimal hyperplasia with luminal obliteration/organized thrombi, fibrous arterial/arteriolar…
  • « Previous Page
  • 1
  • 2
  • 3
  • 4
  • …
  • 19
  • Next Page »
Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

Wiley

  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences

© Copyright 2025 American College of Rheumatology