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Abstracts tagged "Antiphospholipid syndrome and systemic lupus erythematosus (SLE)"

  • Abstract Number: 139 • ACR/ARP Annual Meeting 2019

    Antiphospholipid Syndrome Damage Index (DIAPS): Distinct Long-term Kinetic in Primary Antiphospholipid Syndrome and APS Related to SLE

    Aline Kühl Torricelli1, Michelle Remião Ugolini-Lopes 1, Eloisa Bonfa 2 and Danieli Andrade 3, 1Rheumatology Division - Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo (FMUSP), Sao Paulo, Sao Paulo, Brazil, 2Rheumatology Division, Hospital das Clinicas, Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo, Brazil., Sao Paulo, Sao Paulo, Brazil, 3Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, Brazil

    Background/Purpose: Antiphospholipid syndrome (APS) is an acquired thrombophilia that affects young productive individuals with permanent damage and negative impact in quality of life. Recently a…
  • Abstract Number: 660 • ACR/ARP Annual Meeting 2019

    Antiphospholipid Syndrome (APS) in Systemic Lupus Erythematosus (SLE) Leads to a More Severe Disease

    Leyre Riancho-Zarrabeitia1, Víctor M Martinez-Taboada 2, Iñigo Rua Figueroa 3, Fernando Alonso 4, María Galindo 5, Juan Ovalles-Bonilla 6, Alejandro Olivé-Marqués 7, Antonio Fernández-Nebro 8, Jaime Calvo-Alen 9, Raul Menor Almagro 10, Eva Tomero-Muriel 11, Esther Uriarte Isacelaya 12, Alina Boteanu 13, Mariano Andrés 14, Mercedes Freire González 15, Gregorio Santos Soler 16, Esther Ruiz Lucea 17, Monica Ibañez Barcelo 18, Ivan Castellvi 19, Carles Galisteo 20, Víctor Quevedo Vila 21, Enrique Raya 22, Javier Narváez 23, Lorena Expósito 24, José A Hernández-Beriain 25, Loreto Horcada Rubio 26, Elena Aurrecoechea 27 and Jose Maria Pego-Reigosa 28, 1Hospital Sierrallana, Torrelavega, Spain, 2Hospital Valdecilla, Santander, 3Hospital Doctor Negrin, Las Palmas, 4Unidad Investigación SER, Madrid, Spain, 5Hospital 12 De Octubre, Madrid, 6Hospital Gregorio Marañón, Madrid, Spain, 7Hospital German Trias i Pujol, Badalona, Spain, 8Hospital Carlos Haya, Malaga, Spain, 9Hospital Universitario Araba, Vitoria-Gasteiz, Spain, 10Hospital Universitario de Jerez, Puerto De Santa María, Spain, 11Hospital Universitario La Princesa, Madrid, Spain, 12Hospital Universitario Donosti, San Sebastian, Spain, 13Hospital Universitario Ramón y Cajal, Madrid, Spain, 14Hospital General Universitario de Alicante, Alicante, Spain, 15Hospital Universitario Juan Canalejo, La Coruña, Spain, 16Hospital Marina Baixa, Villajoyosa, Spain, 17Hospital Universitario Basurto, Bilbao, Spain, 18Hospital Universitario Son Llàtzer, Palma de Mallorca, Spain, 19Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, 20Hospital Parc Taulí, Barcelona, Catalonia, Spain, 21Hospital Comarcal Monforte, Monforteº, Spain, 22Hospital Universitario Clínico San Cecilio, Granada, Spain, 23Rheumatology Department, Hospital Universitario de Bellvitge, Barcelona, Spain, Barcelona, Catalonia, Spain, 24Hospital Universitario de Canarias, Las Palmas, Spain, 25Hospital Insular Universitario de Gran Canaria, Las Palmas, Spain, 26Complejo Hospitalario Universitario de Navarra, Pamplona, Spain, 27Rheumatology Department. Hospital Sierrallana, Torrelavega, Spain, 28Complexo Hospitalario Universitario, Vigo, Spain

    Background/Purpose: Antiphospholipid antibodies (aPL) have been associated with organ damage and certain features in SLE patients. Our aim was to investigate the differences between SLE…
  • Abstract Number: 2635 • ACR/ARHP Annual Meeting 2018

    Combined Panel of Nine Tests Has the Greatest Sensitivity but the Lowest Specificity to Detect Antiphospholipid Antibody Syndrome in Patients with Systemic Lupus Erythematosus

    Saika Sharmeen1, Katalin Banki2 and Andras Perl3, 1Medicine, State University of New York Upstate Medical University, Syracuse, NY, 2Clinical Pathology, SUNY Upstate Medical University, Syracuse, NY, 3Medicine, SUNY Upstate Medical University, Syracuse, NY

    Background/Purpose: Antiphospholipid antibody syndrome (APS) is an autoimmune hypercoagulable state caused by antiphospholipid antibodies (aPL) which represent a diagnostic criterion and underlie significant comorbidities in…
  • Abstract Number: 989 • ACR/ARHP Annual Meeting 2013

    Reproductive Counseling Program For Lupus Patients At The Systemic Lupus Erythematosus-Antiphospholipid Syndrome Center Of Excellence At Hospital For Special Surgery

    Katherine Kim1, Alana B. Levine2, Monica C. Richey2, Nadine H. Spring2, Elizabeth Schulman3, Lisa R. Sammaritano2, Shari E. Gelber4 and Jane E. Salmon2, 1Rheumatology, Hospital for Special Surgery, New York, NY, 2Rheumatology, Hospital for Special Surgery, New York, NY, 3Rheumatology, Hospital for Special Surgey, New York, NY, 4Obstetrics, New York Presbyterian Hospital, New York, NY

    Background/Purpose: Maternal exposure to mycophenolate mofetil (MMF) during pregnancy is associated with increased risks of first trimester pregnancy loss and congenital malformations. Responding to this…
  • Abstract Number: 21 • ACR/ARHP Annual Meeting 2013

    Factor Xa Reactive Antibodies In Patients With Systemic LUPUS Erythematosus and Antiphospholipid Syndrome Have Differential Effects Upon Coagulation Assays and Endothelial CELLS

    Bahar Artim-Esen1, Natalia Smoktunowicz2, Charis Pericleous3, Vera M. Ripoll4, Ian Mackie5, Rachel Chambers6, David A. Isenberg7, Anisur Rahman8, Yiannis Ioannou9 and Ian Giles8, 1Rayne Building, 4th Floor, Centre for Rheumatology, University College London, London, United Kingdom, 2Rayne Institute, 1st floor, Respiratory Research Unit, University College London, London, United Kingdom, 3Centre for Rheumatology, Division of Medicine, Centre for Rheumatology, University College London, London, United Kingdom, 4Centre for Rheumatology, Rayne Institute, 4th floor, Centre for Rheumatology, University College London, London, United Kingdom, 5Haemostasis Research Unit, 1st Floor, 51 Chenies Mews, Haemostasis Research Unit, University College London, London, United Kingdom, 6Center for Respiratory Research, Rayne Institute, 1st floor, University College London, London, United Kingdom, 7Centre for Rheumatology Research, Rayne Building, 4th Floor, Centre for Rheumatology, Department of Medicine, University College London, London, United Kingdom, 8Centre for Rheumatology Research,Rayne Institute, 4th Floor, University College London, London, United Kingdom, 9Arthritis Research UK Centre for Adolescent Rheumatology, University College London, London, United Kingdom

    Background/Purpose:   Antiphospholipid antibodies have been shown to bind serine proteases (SP) involved in the coagulation cascade. Previously, we found that IgG anti-Factor(F)Xa antibody levels…
  • Abstract Number: 9 • ACR/ARHP Annual Meeting 2013

    Domain 1 Is The Main Specificity Of Anti-β2glycoprotein I Antibodies In Systemic Autoimmune Diseases

    Laura Andreoli1, Cecilia Nalli1, Maria-Orietta Borghi2, Francesca Pregnolato3, Alessandra Zanola4, Claudia Grossi5, Maria Gerosa6, Flavio Allegri4, Michael Mahler7, Gary L. Norman7, Pier Luigi Meroni8 and Angela Tincani1, 1Rheumatology Unit, University of Brescia, Brescia, Italy, 2Lab of immunology, IRCCS Istituto Auxologico Italiano, Department of Clinical Sciences and Community Health, University of Milan, Milano, Italy, 3Lab of Immunology, IRCCS Istituto Auxologico Italiano, Milan, Italy, 4Rheumatology and Clinical Immunology, Spedali Civili and University of Brescia, Brescia, Italy, 5Laboratory of Immuno-rheumatology, IRCCS Istituto Auxologico Italiano, Milan, Italy, 6Division of Rheumatology, Gaetano Pini Institute, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy, 7Research, INOVA Diagnostics, San Diego, CA, 8Division of Rheumatology, Gaetano Pini Institute, Milano, Italy

    Background/Purpose: Anti-β2glycoprotein I antibodies (a-β2GPI) are involved in the pathogenesis of the Antiphospholipid Syndrome (APS). Antibodies to the domain 1 of β2GP1 (a-β2GPI-D1) have been…
  • Abstract Number: 1738 • ACR/ARHP Annual Meeting 2012

    Myocardial Dysfunction and Valvulopathy Worsens with Time in Patients with Antiphospholipid Syndrome: A 10-Year Follow-up Study

    MG Tektonidou1, CF Kampolis2, I. Moyssakis3, GE Tzelepis2, Haralampos M. Moutsopoulos2 and P. Vlachoyiannopoulos2, 1First Department of Internal Medicine, University of Athens Medical School, Laiko Hospital, Athens, Greece, 2Department of Pathophysiology, University of Athens Medical School, Laiko Hospital, Athens, Greece, 3Department of Cardiology, Laiko Hospital, Athens, Greece

    Background/Purpose: Valvular disease represents the most common cardiac manifestation among patients with antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) positive for antiphospholipid antibodies (aPL).…
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