Abstracts tagged "antiphospholipid syndrome and statins"

Abstract Number: 2457 • 2012 ACR/ARHP Annual Meeting
An Open-Label Prospective Pilot Mechanistic Study of Fluvastatin in Persistently Antiphospholipid Antibody-Positive Patients
Doruk Erkan¹, Rohan Willis², JoAnn Vega³, Vijaya L. Murthy², Ana Laura Carrera Marin⁴, Gurjot Basra², Patricia Ruiz Limon², Emilio B. Gonzalez² and Silvia S. Pierangeli², ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Rheumatolgoy/Dept Int Med, University of Texas Medical Branch, Galveston, TX, ³Research, Hospital for Special Surgery, New York, NY, ⁴Rheumatology/Dept Int Med, University of Texas Medical Branch, Galveston, TX
Background/Purpose: Antiphospholipid antibodies (aPL) induce a pro-inflammatory and pro-thrombotic state by upregulating various cytokines, chemokines, and tissue factor (TF). Fluvastatin reduces TF expression and decrease…

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Abstracts tagged "antiphospholipid syndrome and statins"

An Open-Label Prospective Pilot Mechanistic Study of Fluvastatin in Persistently Antiphospholipid Antibody-Positive Patients