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Abstracts tagged "Antiphospholipid syndrome and genetics"

  • Abstract Number: 1961 • ACR/ARHP Annual Meeting 2016

    Identification of Novel Genetic Susceptibility Loci in Primary Antiphospholipid Syndrome

    Elizabeth Gensterblum1, Travis Hughes2, Manuel Martínez-Bueno3, Maria Orietta Borghi4, Guillermo J. Pons-Estel5, Gerard Espinosa6, Alexandra Zhernakova7, Cisca Wijmenga8, Ricard Cervera5, Pier Luigi Meroni9, Marta Alarcón-Riquelme3,10 and Amr Sawalha1, 1Division of Rheumatology, University of Michigan, Ann Arbor, MI, 2Division of Health Sciences and Technology, Harvard Medical School, Boston, MA, 3Center for Genomics and Oncological Research (GENYO), Pfizer-University of Granada-Andalusian Regional Government, Health Sciences Technology Park, Granada, Spain, 4University of Milan, IRCCS Istituto Auxologico Italiano, Milan, Italy, 5Department of Autoimmune Diseases, Institut Clínic de Medicina i Dermatologia, Hospital Clínic de Barcelona, Barcelona, Spain, 6Autoimmune Diseases Department. Hospital Clínic de Barcelona, Barcelona, Spain, 7Rheumatology and Clinical Immunology, University of Groningen, University Medical Center, Groningen, Netherlands, 8Genetics, University Medical Hospital Groningen, University of Groningen, Groningen, Netherlands, 9Hospital G.Pini, University of Milano, IRCSS Instute Auxologico Italiano, Milan, Italy, 10Unit for Chronic Inflammatory Diseases, Institute for Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

    Background/Purpose:  Antiphospholipid syndrome (APS) is an autoimmune disease with incompletely understood etiology, characterized by recurrent thrombosis and pregnancy complications. We conducted this study to understand…

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