Abstracts tagged "antiphospholipid syndrome and beta2 Glycoprotein I"

Abstract Number: 566 • ACR/ARHP Annual Meeting 2013
A Human Monoclonal Antibody Against Domain I Of β2-Glycoprotein I prevents Clotting and Fetal Loss Induced By Polyclonal Anti-Phospholipid Antibodies In Animal Models
Chiara Agostinis¹, Paolo Durigutto², Daniele Sblattero², Maria Orietta Borghi^3,4, Claudia Grossi⁴, Roberta Bulla², Paolo Macor², Pier Luigi Meroni^3,5 and Francesco Tedesco², ¹Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy, ²Department of Life Sciences, University of Trieste, Trieste, Italy, ³Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy, ⁴Laboratory of Immuno-rheumatology, IRCCS Istituto Auxologico Italiano, Milan, Italy, ⁵Department of Clinical Sciences and Community Health, Division of Rheumatology, Istituto G. Pini, Milan, Italy
Background/Purpose: Anticoagulant, antiplatelet or immunosuppressive therapy are currently used to treat the clinical manifestations of the anti-phospholipid syndrome (APS). Side effects or recurrences in spite…