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Abstracts tagged "Antiphospholipid antibodies and systemic lupus erythematosus (SLE)"

  • Abstract Number: 2629 • 2018 ACR/ARHP Annual Meeting

    Longitudinal Analysis of Persistent Positivity of Antiphospholipid Antibodies in Systemic Lupus Erythematosus

    Michelle Petri1, Mertcan Avci2 and Laurence S Magder3, 1Medicine (Rheumatology), Johns Hopkins University School of Medicine, Baltimore, MD, 2Medicine, Istanbul Faculty of Medicine, Istanbul, Turkey, 3Epidemiology and Preventive Medicine, University of MD, Baltimore, MD

    Background/Purpose: ‘Persistent positivity” has been a part of laboratory criteria for antiphospholipid syndrome classification criteria and requires two positive tests. We investigated the clinical utility…
  • Abstract Number: 703 • 2017 ACR/ARHP Annual Meeting

    Clinical Value of Autoantibodies for Lupus Myelitis and Its Subtypes: A Systematic Review

    Hiroshi Oiwa1, Akira Kuriyama2, Tomoyasu Matsubara3 and Eiji Sugiyama4, 1Rheumatology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan, 2General Medicine, Kurashiki Central Hospital, Kurashiki, Japan, 3Neurology, Hiroshima University Hospital, Hiroshima, Japan, 4Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan

    Background/Purpose: We conducted a systematic review to investigate the clinical value of clinical characteristics and autoantibodies, especially lupus-specific antibodies, for lupus myelitis and its subtypes.…
  • Abstract Number: 2188 • 2015 ACR/ARHP Annual Meeting

    Antiphospholipid Antibodies and the Risk of Damage Accrual in Systemic Lupus Erythematosus

    Mara Taraborelli1, Laura Leuenberger2, Maria Grazia Lazzaroni3, Nicole Martinazzi3, Wei Zhang4, Jane E. Salmon2, Franco Franceschini1, Angela Tincani3 and Doruk Erkan2, 1Rheumatology and Clinical Immunology, Spedali Civili of Brescia, Brescia, Italy, 2Rheumatology, Hospital for Special Surgery, New York, NY, 3Rheumatology and Clinical Immunology, Spedali Civili and University of Brescia, Brescia, Italy, 4Healthcare Research Institute, Hospital for Special Surgery, New York, NY

    Background/Purpose: A limited number of studies evaluated the impact of antiphospholipid antibodies (aPL) on organ damage in Systemic Lupus Erythematosus (SLE) with contrasting conclusions. The…
  • Abstract Number: 2202 • 2015 ACR/ARHP Annual Meeting

    Different Patterns of Positivity for IgG Anti-Cardiolipin, Anti-Beta-2-Glycoprotein I and Anti-Domain I Antibodies within the First Year of Disease in 501 Patients with SLE  – Associations  with Different Clinical Outcomes

    Amrita D'Souza1, Charis Pericleous2, Oliver Leach1, Karim Fouad Alber1, Thomas McDonnell2, Yiannis Ioannou2, Ian Giles3, David A. Isenberg4 and Anisur Rahman5, 1Centre for Rheumatology Research, University College London, London, United Kingdom, 2Rayne Institute, Centre for Rheumatology Research, UCL Division of Medicine, London, United Kingdom, 3Rayne Intitiute, Centre for Rheumatology Research, UCL Division of Medicine, London, United Kingdom, 4Centre for Rheumatology Research, Rayne Building, 4th Floor, Centre for Rheumatology, Department of Medicine, University College London, London, United Kingdom, 5Centre for Rheumatology Research,Rayne Institute, 4th Floor, University College London, London, United Kingdom

    Background/Purpose: Antiphospholipid Syndrome (APS) is an autoimmune rheumatic disorder in which antiphospholipid antibodies (aPL) cause clinical sequelae including vascular events (VE) and pregnancy morbidity (PM).…
  • Abstract Number: 18 • 2014 ACR/ARHP Annual Meeting

    The Effect of Clinically Significant Antiphospholipid Antibody Positivity on Organ Damage in Systemic Lupus Erythematosus

    Mara Taraborelli1, Laura Leuenberger2, Wei Zhang3, Angela Tincani1, Jane Salmon2 and Doruk Erkan2, 1Rheumatology and Clinical Immunology, Spedali Civili and University of Brescia, Brescia, Italy, 2Rheumatology, Hospital for Special Surgery, New York, NY, 3Healthcare Research Institute, Hospital for Special Surgery, New York, NY

    Background/Purpose: The effect of antiphospholipid antibodies (aPL) on organ damage in Systemic Lupus Erythematosus (SLE) patients remains unclear as there are limited number of studies…
  • Abstract Number: 3 • 2014 ACR/ARHP Annual Meeting

    Is There an Association Between Persistently High Positive Antiphospholipid Antibody Profile and Organ Damage Accrual in Lupus Patients?

    Doruk Erkan1, Lisa G. Criscione-Schreiber2, Maria Dall'era3, Olga Dvorkina4, Russell Griffin5, Galina Marder6, Maureen A. McMahon7, Jorge Sanchez-Guerrero8, Amit Saxena9 and Robert Roubey10, 1Rheumatology, Hospital for Special Surgery, New York, NY, 2Dept of Med/Rheum Div, Duke University School of Medicine, Durham, NC, 3Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, 4Medicine, SUNY Health Science Center at Brooklyn, Brooklyn, NY, 5University of Alabama at Birmingham, Birmingham, AL, 6Medicine, North Shore Long Island Health System, Great Neck, NY, 7Division of Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, 8UHN Toronto Western Hospital, Toronto, ON, Canada, 9Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, 10Division of Rheumatology and Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC

    Background/Purpose: Few studies assessed the impact of antiphospholipid antibodies (aPL) on organ damage in lupus with conflicting results. Our objective was to determine if persistently…
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