Abstracts tagged "antiphospholipid antibodies and cerebrovascular disease"

Abstract Number: 2863 • ACR/ARHP Annual Meeting 2014
IgG Antiphospholipid Antibodies Enhance Stroke Damage: An in Vivo Ischemia/Reperfusion Study
Charis Pericleous¹, Valerie Taylor², Lauren Bourke³, Daniel Stuckey², Jed Wingrove⁴, Mark Lythgoe⁵, Silvia S. Pierangeli⁶, Anisur Rahman³, Ian Giles¹ and Yiannis Ioannou⁷, ¹Centre for Rheumatology, Division of Medicine, Centre for Rheumatology, University College London, London, United Kingdom, ²Centre for Advanced Biomedical Imaging (CABI), University College London, London, United Kingdom, ³Centre for Rheumatology Research, University College London, London, United Kingdom, ⁴Centre for Advanced Biomedical Imaging, University College London, London, United Kingdom, ⁵Centre for Advanced Biomedical Imaging, Centre for Advanced Biomedical Imaging (CABI), University College London, London, United Kingdom, ⁶Rheumatology/Dept Int Med, University of Texas Medical Branch, Galveston, TX, ⁷Centre for Rheumatology Research, University College Hospital London, London, United Kingdom
Background/Purpose Circulating pathogenic antiphospholipid antibodies (aPL) are the hallmark of antiphospholipid syndrome (APS) and a major risk factor for ischemic stroke, with up to one…