Abstracts tagged "Antinuclear antibodies (ANA)"

Abstract Number: 1268 • 2014 ACR/ARHP Annual Meeting
Study of Autoantibodies in a cohort of Mexican patients with idiopathic inflammatory myopathies
Yelitza Gonzalez-Bello¹, Miguel Angel Ortiz-Villalvazo², Ignacio Garcia-Valladares¹, Gabriel Medrano-Ramírez³, José E. Navarro-Zarza⁴, Lilia Andrade-Ortega⁵, Arnulfo Nava-Zavala⁶, Gerardo Orozco-Barocio¹, Marco Maradiaga-Ceceña⁷, Marvin Fritzler⁸ and Ignacio Garcia-De La Torre⁹, ¹Immunology and Rheumatology, Hospital General de Occidente, Zapopan, Jal., Mexico, ²Internal Medicine, Hospital Civil de Guadalajara, Guadalajara, Jal., Mexico, ³Rheumatology, Hospital General de Mexico de la Secretaría de Salud, Mexico City, Mexico, ⁴Rheumatology, Hospital General de Chilpancingo, Chilpancingo, Gro., Mexico, ⁵Rheumatology, CMN 20 Noviembre ISSSTE, Mexico City, Mexico, ⁶Rheumatology, Hospital General de Occidente, Zapopan, Jal., Mexico, ⁷Rheumatology, Hospital General de Culiacan de la Secretaría de Salud, Culiacan, Sin., Mexico, ⁸Medicine, University of Calgary, Calgary, AB, Canada, ⁹Immunology and Rheumatology, Universidad de Guadalajara, Guadalajara, Jal., Mexico
Background/Purpose Idiopathic inflammatory myopathies (IIM) are a group of autoimmune disorders characterized by muscle inflammation, progressive weakness with a combination of clinical, electromyography and laboratory…
Abstract Number: 413 • 2014 ACR/ARHP Annual Meeting
Association of Antinuclear Antibodies with Lung Disease, Malignancy and Joint Replacement in Rheumatoid Arthritis
Reshmi Raveendran¹, Bobby Kwanghoon Han², Quan-Zhen Li³ and Nancy J. Olsen¹, ¹Medicine, Penn State MS Hershey Medical Center, Hershey, PA, ²Rheumatology, Cooper Medical School of Rowan University, Camden, NJ, ³Immunology, University of Texas Southwestern Medical Center, Dallas, TX
Background/Purpose Antinuclear antibodies (ANAs) are present in a significant proportion of patients with rheumatoid arthritis (RA). Positivity for ANA in RA has been associated with…
Abstract Number: 2893 • 2013 ACR/ARHP Annual Meeting
Intestinal Microbiota Plays a Critical Role In The Production Of Antinuclear Antibodies In Lymphopenia-Induced Autoimmunity
Toshiki Eri¹, Kimito Kawahata¹, Mitsuru Imamura¹, Takeyuki Kanzaki², Lisa Akahira¹, Kazuya Michishita¹, Makoto Dohi¹, Takeshi Tokuhisa³ and Kazuhiko Yamamoto⁴, ¹Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, ²Internal Medicine, Yamanashi Prefectural Central Hospital, Yamanashi, Japan, ³Development Genetics, Graduate School of Medicine, Chiba University, Chiba city, Chiba, Japan, ⁴Department of Allergy and Rhaumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Background/Purpose: Production of antinuclear autoantibodies (ANAs) is one of the major characteristics of the systemic autoimmune diseases, such as systemic lupus erythematosus (SLE), but the…
Abstract Number: 671 • 2013 ACR/ARHP Annual Meeting
Autoantibody Diversity In Scleroderma Patients With Antinucleolar Antibodies and Negative For Three Major Disease-Specific Markers
Sarada Nandiwada¹, Troy Jaskowski², Maureen D. Mayes³, Minoru Satoh⁴ and Anne E. Tebo¹, ¹Pathology, University of Utah, Salt Lake City, UT, ²ARUP Laboratories, Salt Lake City, UT, ³University of Texas Health Science Center at Houston, Houston, TX, ⁴Medicine, University of Florida, Gainesville, FL
Background/Purpose: Antinuclear antibodies (ANA) in a nucleolar pattern (antinucleolar antibodies, ANoA) by indirect immunofluorescence technique correlate with several autoantibody specificities and clinical manifestations in scleroderma…
Abstract Number: 713 • 2012 ACR/ARHP Annual Meeting
Rpp25 Is a Major Target of Autoantibodies to the Th/to Complex As Measured by ELISA and a New Chemilumiscence Assay
Michael Mahler¹, Cristina Gascon², Sima Patel², Angela Ceribelli³, Edward K.L. Chan³ and Minoru Satoh⁴, ¹Research, INOVA Diagnostics, San Diego, CA, ²Research, INOVA Diagnostics, Inc., San Diego, CA, ³Oral Biology, University of Florida, Gainesville, FL, ⁴Medicine, University of Florida, Gainesville, FL
Background/Purpose: Anti-nuclear antibodies (ANA) play an important role in the diagnosis of systemic autoimmune diseases including systemic sclerosis (SSc). A significant portion of ANA in…
Abstract Number: 197 • 2012 ACR/ARHP Annual Meeting
Collapsing Glomerulopathy in Collagen Vascular-Like Disease
Rawad Nasr¹, Christine Johns² and Elie Gertner³, ¹Rheumatology - Internal Medicine, University of Minnesota, Minneapolis, MN, ²Section of Nephrology, Regions Hospital, St Paul, MN, ³Section of Rheumatology, Regions Hospital and University of Minnesota Medical School, St. Paul, MN
Background/Purpose: Background: Collapsing Glomerulopathy (CG) is an uncommon podocytopathy with distinct clinical and pathological characteristics. It is usually associated with HIV disease or parvovirus B19…
Abstract Number: 1405 • 2012 ACR/ARHP Annual Meeting
Real World Experience Comparing Multiplex Immunobead Assay versus Immunoflorescence Assay for Anti-Nuclear Antibody Detection At a University Hospital
Neha Dang¹, Brock E. Harper², Emilio B. Gonzalez¹, Silvia S. Pierangeli¹, Trisha M. Parekh³, Michael J. Loeffelholz⁴ and Kimberly K. Bufton⁵, ¹Rheumatology/Dept Int Med, University of Texas Medical Branch, Galveston, TX, ²Int Med/Rheumatology, University of Texas Medical Branch, Galveston, TX, ³Internal Medicine, University of Texas Medical Branch, Galveston, TX, ⁴Pathology, University of Texas Medical Branch, Galveston, TX, ⁵Microbiology, University of Texas Medical Branch, Galveston, TX
Background/Purpose: Anti-nuclear antibody (ANA) is considered a screening method for diagnosis of autoimmune disorders. Immunoflorescence ANA assay (IF) remains the gold standard for detection of…
Abstract Number: 948 • 2012 ACR/ARHP Annual Meeting
Antibody-Based Prediction Rules for Connective Tissue Disease: Analysis of 12,555 Patients with Antinuclear Antibody Testing
Ryo Rokutanda¹, Mitsumasa Kishimoto¹, Yasuharu Tokuda², Ken-ichi Yamaguchi¹, Hisanori Shimizu¹, Yasuhiro Suyama¹, Yuri Ohara¹, Yoichiro Haji¹, Chisun Min¹, Akira Takeda¹, Yukio Matsui³ and Masato Okada¹, ¹Division of Allergy and Rheumatology, St. Luke's International Hospital, Tokyo, Japan, ²Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan, ³Immuno-Rheumatology Center, St. Luke's International Hospital, Tokyo, Japan
Background/Purpose: Antinuclear antibody (ANA) is widely used as a screening test for connective tissue diseases (CTDs). The sensitivity of this test is high in 3…
Abstract Number: 949 • 2012 ACR/ARHP Annual Meeting
The Inverse Association Between Obesity and Anti-Nuclear Antibodies Is Modified by Systemic Inflammation and Maybe Associated with Body Composition
Irene Blanco¹, Monalyn Labitigan¹ and Matthew Abramowitz², ¹Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ²Nephrology, Albert Einstein College of Medicine, Bronx, NY
Background/Purpose: Obesity and abdominal adiposity have been frequently associated with inflammation. However, an association of obesity with a decreased likelihood of anti-nuclear antibodies (ANAs) was…
Abstract Number: 950 • 2012 ACR/ARHP Annual Meeting
Performance of Various Anti-Nuclear Antibody Methodologies in the Assessment of Autoimmune Connective Tissue Diseases
Xiaoli Deng¹, Cynthia S. Crowson², Helen Khun², Melissa R. Snyder³ and Kevin G. Moder⁴, ¹Mayo Clinic, Rochester, MN, ²Department of Health Sciences Research, Mayo Clinic, Rochester, MN, ³2Division of Clinical Biochemistry and Immunology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, ⁴Rheumatology, Mayo Clinic, Rochester, MN
Background/Purpose : The anti-nuclear antibody (ANA) is the classic biomarker associated with autoimmune connective tissue diseases (CTDs). ANA testing is often ordered as part of…

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