anti-TNF therapy and methotrexate (MTX) Archives

Abstract Number: 1823 • ACR/ARHP Annual Meeting 2017
Methotrexate Requires High Serum BAFF Levels to Prevent Immunization Against TNF-α Inhibitors
Samuel Bitoun¹, Pierre Dönnes², Aline Doublet³, Kimberly Florence⁴, Agnes Hincelin-Mery⁵, Gaetane Nocturne⁶, Mattieu Allez⁷, N Ruperto⁸, Marc Pallardy⁹ and Xavier Mariette¹⁰, ¹INSERM U1184, IMVA, Paris Sud University,LabEx LERMIT, Le Kremlin Bicëtre, France, ²SciCross AB, Skövde, Sweden, ³Department of Rheumatology, Kremlin-Bicêtre hospital INSERM U1184, Le Kremlin Bicêtre, France, ⁴Immunogenicity and Clinical Immunology, GlaxoSmithKline, King of Prussia, PA, ⁵Sanofi, Chilly-Mazarin, France, ⁶INSERM U1184, IMVA, Paris Sud University,LabEx LERMIT, Le Kremlin Bicêtre, France, ⁷Department of Gastroenterology, Hopital Saint-Louis, APHP, Paris, France, ⁸PRINTO Coordinating Centre, Genoa, Italy, ⁹Inflammation, Chimiokines et Immunopathologie, INSERM UMR 996, Faculté de Pharmacie, Chatenay Mallabry, France, ¹⁰Université Paris Sud, Paris, France
Background/Purpose: Immunization against TNF Inhibitors (TNFi) is observed in 30-50% of patients with inflammatory rheumatic diseases. With most TNFi, anti-drug antibodies (ADA) lead to rapid…
Abstract Number: 142 • ACR/ARHP Annual Meeting 2015
Exploration of General Practioners’ Difficulties with Methotrexate and Anti-TNF Therapies in Routine Practice
Elise Berthet¹, Virginie Moiroud², Marion De Rosa², Martin Soubrier³ and Sylvain Mathieu⁴, ¹Rheumatology, CHU Gabriel Montpied, Clermont-Ferrand, France, ²Médecine Générale, CHU Gabriel Montpied, Clermont-Ferrand, France, ³Rheumatology department CHU Clermont-Ferrand, Clermont-Ferrand, France, ⁴Rheumatology Department, CHU clermont-Ferrand, Clermont-Ferrand, France
Background/Purpose: Chronic inflammatory arthritis affects around 1% of the general population. Disease-modifying drugs like methotrexate (MTX) and in second-line anti tumor necrosis factor (anti-TNF) therapy…

Abstracts tagged "anti-TNF therapy and methotrexate (MTX)"

Methotrexate Requires High Serum BAFF Levels to Prevent Immunization Against TNF-α Inhibitors

Exploration of General Practioners’ Difficulties with Methotrexate and Anti-TNF Therapies in Routine Practice