ACR Meeting Abstracts

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Abstracts tagged "anti-TNF therapy and biomarkers"

  • Abstract Number: 575 • 2012 ACR/ARHP Annual Meeting

    Profiling of Response to Anti-TNFα Therapy by Serum Markers of Tissue Degradation End Products in Ankylosing Spondylitis Patients

    Anne Sofie Siebuhr1, Anne C. Bay-Jensen2, Morten Asser Karsdal3, Efstathios Vassiliadis4, Stephanie Wichuk5, Claus Christiansen6 and Walter P. Maksymowych7, 1Rheumatology, Nordic Bioscience, Herlev, Denmark, 2Cartilage Biomarkers and Research, Nordic Bioscience, Herlev, Denmark, 3Nordic Bioscience A/S, Herlev, Denmark, 4Nordic Bioscience, Herlev, Denmark, 5Medicine, University of Alberta, Edmonton, AB, Canada, 6CCBR, Ballerup, Denmark, 7Department of Medicine, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: Chronic inflammatory diseases such as Ankylosing Spondylitis (AS) are diverse and therefore hard to clearly diagnose and treat. Conventional biomarkers for AS, as CRP…
  • Abstract Number: 538 • 2012 ACR/ARHP Annual Meeting

    Association Between Biomarkers (Metalloproteinase-3, Dikkopf-1 and Sclerostin) with Disease Activity and Prediction of Anti-TNFá Therapy Response in Patients with Ankylosing Spondylitis

    Victoria Navarro-Compán1, Rafael Ariza2, Rufino Mondéjar-García3, Virginia Moreira-Navarrete4, Enrique Melguizo-Madrid3, Blanca Hernández-Cruz4, Concepción González-Rodríguez3 and Federico Navarro-Sarabia5, 1Leiden University Medical Center, Leiden, Netherlands, 2Rheumatology, University Hospital Virgen Macarena.Sevilla, Sevilla, Spain, 3Biochemistry, University Hospital Virgen Macarena, Sevilla, Spain, 4Rheumatology, University Hospital Virgen Macarena, Sevilla, Spain, 5Rheumatology, Hospital Virgen Macarena, Serv. de Reumatología, Sevilla, Spain

    Background/Purpose: Better objectives measures for evaluating disease activity and anti-TNFα response in patients with ankylosing spondylitis (AS) are needed. MMP-3 seems to be the most…
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