Abstracts tagged "anti-citrullinated protein/peptide antibodies (ACPA) and Early Rheumatoid Arthritis"

Abstract Number: 841 • 2019 ACR/ARP Annual Meeting
Elevation of Anti-Citrullinated Protein Antibodies Prior to Rheumatoid Arthritis Onset and Risks for Developing Chronic Obstructive Pulmonary Disease or Asthma
Alessandra Zaccardelli¹, Xinyi Liu ¹, Julia Ford ¹, Jing Cui ¹, Bing Lu ¹, Su H. Chu ², Peter Schur ¹, Cameron Speyer ¹, Karen Costenbader ¹, William Robinson ³, Jeremy Sokolove ⁴, Elizabeth Karlson ¹, Carlos Camargo ⁵ and Jeffrey Sparks ¹, ¹Brigham and Women's Hospital, Boston, MA, ²Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ³Stanford University, Stanford, CA, ⁴AbbVie Immunology Clinical Development, Redwood City, ⁵Massachusetts General Hospital, Boston, MA
Background/Purpose: Elevation of anti-citrullinated protein antibodies (ACPA) precedes clinical rheumatoid arthritis (RA) diagnosis by years and may originate at inflamed mucosa, including airways. Damage from…