Abstracts tagged "anti-CCP antibodies and anti-citrullinated protein/peptide antibodies (ACPA)"

Abstract Number: 2668 • 2015 ACR/ARHP Annual Meeting
Effect of Anti-Cyclic Citrullinated Peptide 2 Immunoglobulin M Serostatus on Efficacy Outcomes Following Treatment with Abatacept Plus Methotrexate
T. W. J. Huizinga¹, SE Connolly², A Johnsen², J Zhu², Daniel E. Furst³, VP Bykerk⁴, Gerd Burmester⁵, BG Combe⁶, DA Wong², LA Trouw¹, René E. M. Toes¹ and Paul Emery⁷, ¹Leiden University Medical Center, Leiden, Netherlands, ²Bristol-Myers Squibb, Princeton, NJ, ³Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, ⁴Weill Cornell Medical College, New York, NY, ⁵Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany, ⁶Montpellier University, Montpellier, France, ⁷University of Leeds, Leeds, United Kingdom
Background/Purpose: Anti-citrullinated protein antibodies (ACPA) are a marker of RA, and the presence of the immunoglobulin M (IgM) isotype indicates an ongoing immune response involving…

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